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Comparison of Lumbar Muscle Thickness Measurements in Osteoporotic and Osteopenic Patients

Sponsor
Sisli Hamidiye Etfal Training and Research Hospital (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05823558
Collaborator
(none)
300
Enrollment
3
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

In osteoporosis, sarcopenia is a common condition. Sarcopenic measurements can be made by evaluating muscle thickness in different regions. We aim to evaluate lumbar muscle losses in patients with osteoporosis in the lumbar region and to examine whether these muscle losses are correlated with the level of osteoporosis. The patients will be divided into 3 groups as healthy, osteopenic and osteoporotic according to DEXA measurements. Demographic values, comorbidities, osteoporosis drugs used, fracture histories, L1-4, L2-4, femoral neck and total BMD and t values of the patients, psoas and multifidus muscle measurements will be made at L2-L3 level in Lumbar MR imaging. Lumbar MR muscle measurements will be made by 1 physician blind to the DEXA values of the patients.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: Lomber Muscle Thickness Measurement

Study Design

Study Type:
Observational
Anticipated Enrollment :
300 participants
Observational Model:
Case-Crossover
Time Perspective:
Cross-Sectional
Official Title:
Comparison of Lumbar Muscle Thickness Measurements in Osteoporotic and Osteopenic Patients
Anticipated Study Start Date :
May 1, 2023
Anticipated Primary Completion Date :
Jul 1, 2023
Anticipated Study Completion Date :
Aug 1, 2023

Arms and Interventions

Arm Intervention/Treatment
Ostoporotic Patients Group

T value of -2.5 and below in DEXA measurement

Diagnostic Test: Lomber Muscle Thickness Measurement
Muscle thickness measurements will be made on the imaging of those who have lumbar MR imaging.
Osteopenic Patients Group

T value between -2.5 and -1 in DEXA measurement

Diagnostic Test: Lomber Muscle Thickness Measurement
Muscle thickness measurements will be made on the imaging of those who have lumbar MR imaging.
Healthy Group

T value of -1 and above in DEXA measurement

Diagnostic Test: Lomber Muscle Thickness Measurement
Muscle thickness measurements will be made on the imaging of those who have lumbar MR imaging.

Outcome Measures

Primary Outcome Measures

  1. Lomber Muscle Measurement [Day 1]

    Psoas and multifidus muscle measurements will be made at L2-L3 level in Lumbar MR imaging.

Eligibility Criteria

Criteria

Ages Eligible for Study:
50 Years to 90 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:

  • 50-90 years old

    1. Recent MRI of the lumbar region with DEXA evaluation
Exclusion Criteria:

  • Have had previous lumbar surgery

  • Any previous lumbar injection

  • Stage 3-4 Lumbar Listesis

  • Presence of Lumbar Discopathy accompanied by neurological deficit

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Sisli Hamidiye Etfal Training and Research Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Aylin Ayyıldız, Medical Doctor, Sisli Hamidiye Etfal Training and Research Hospital
ClinicalTrials.gov Identifier:
NCT05823558
Other Study ID Numbers:
  • 10042023
First Posted:
Apr 21, 2023
Last Update Posted:
Apr 21, 2023
Last Verified:
Apr 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:
Osteoporosis

Study Results

No Results Posted as of Apr 21, 2023