ImagNimes: The Complex Regional Pain Syndrome (CRPS) is a Chronic Pain Condition. This is a Preliminary Study to Explore and Test Clinical Hypothesis. They Suppose That CRPS Patients Have Impairment in Their Mental or Motor Imagery Abilities.

Sponsor

Centre Hospitalier Universitaire de Nīmes (Other)

Overall Status

Recruiting

CT.gov ID

NCT04703348

Collaborator

(none)

150

Enrollment

Location

Arms

35.6

Anticipated Duration (Months)

4.2

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Medical functional imagery seems to demonstrate that patients suffering from complex regional pain syndrome (CRPS) have cortical modifications that alter their motor (or mental) imagery capacities. Nowadays, the use of motor imagery exercises are used in conventional rehabilitation treatments. But, in clinical practice, no study has verified if patients with CRPS desmonstrate problems in their motor imagery capacities. The MIQ-RS (Motor Imagery Questionnaire - Revised Second) is a valid, reliable and translated into French questionnaire to measure patients' capacities to do mental imagery. In this study, we compare 3 groups of 50 patients : healthy patients, patients with CRPS and patients with musculoskeletal disorder without CRPS. Every patient will take the MIQ-RS for the right and left body side. We hypothesis that patients with CRPS have more deficit than the 2 others to realise motor imagery.

Condition or Disease	Intervention/Treatment	Phase
Complex Regional Pain Syndromes Musculoskeletal Pain Disorder Healthy	Diagnostic Test: Motor imagery Questionnaire - Revised Second (MIQ-RS)	N/A

Study Design

Study Type:

Interventional

Anticipated Enrollment :

150 participants

Allocation:

Non-Randomized

Intervention Model:

Parallel Assignment

Intervention Model Description:

3 groups with different healthcare conditions are compared in motor imagery capacities3 groups with different healthcare conditions are compared in motor imagery capacities

Masking:

None (Open Label)

Primary Purpose:

Screening

Official Title:

Pilot Study on the Assessment of Motor Imaging Skills in Patients With Complex Regional Pain Syndrome (CRPS)

Actual Study Start Date :

Jan 12, 2021

Anticipated Primary Completion Date :

Jan 1, 2024

Anticipated Study Completion Date :

Jan 1, 2024

Arms and Interventions

Arm	Intervention/Treatment
Other: Healthy patients Healthy patients take the MIQ-RS during about 40 minutes : about 20 minutes for the assessment of the right side and about 20 minutes for the left side	Diagnostic Test: Motor imagery Questionnaire - Revised Second (MIQ-RS) Patients fulfill a questionnaire measuring individuals capacities to realize mental imagery. For more facilities and less risk of bias, the MIQ-RS was written on an online version with questions recorded in audio format. No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery a score between 49 and 73/98 have disturbed motor imagery capacities a score more than 74/98 have normal motor imagery capacities.
Other: Complex regional pain syndrome patients Complex regional pain syndrome patients take the MIQ-RS during about 40 minutes : about 20 minutes for the assessment of the right side and about 20 minutes for the left side	Diagnostic Test: Motor imagery Questionnaire - Revised Second (MIQ-RS) Patients fulfill a questionnaire measuring individuals capacities to realize mental imagery. For more facilities and less risk of bias, the MIQ-RS was written on an online version with questions recorded in audio format. No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery a score between 49 and 73/98 have disturbed motor imagery capacities a score more than 74/98 have normal motor imagery capacities.
Other: Musculoskelettal disorders patients Musculoskelettal disorders patients take the MIQ-RS during about 40 minutes : about 20 minutes for the assessment of the right side and about 20 minutes for the left side	Diagnostic Test: Motor imagery Questionnaire - Revised Second (MIQ-RS) Patients fulfill a questionnaire measuring individuals capacities to realize mental imagery. For more facilities and less risk of bias, the MIQ-RS was written on an online version with questions recorded in audio format. No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery a score between 49 and 73/98 have disturbed motor imagery capacities a score more than 74/98 have normal motor imagery capacities.

Arm

Intervention/Treatment

Other: Healthy patients

Healthy patients take the MIQ-RS during about 40 minutes : about 20 minutes for the assessment of the right side and about 20 minutes for the left side

Diagnostic Test: Motor imagery Questionnaire - Revised Second (MIQ-RS)

Patients fulfill a questionnaire measuring individuals capacities to realize mental imagery. For more facilities and less risk of bias, the MIQ-RS was written on an online version with questions recorded in audio format. No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery a score between 49 and 73/98 have disturbed motor imagery capacities a score more than 74/98 have normal motor imagery capacities.

Other: Complex regional pain syndrome patients

Complex regional pain syndrome patients take the MIQ-RS during about 40 minutes : about 20 minutes for the assessment of the right side and about 20 minutes for the left side

Diagnostic Test: Motor imagery Questionnaire - Revised Second (MIQ-RS)

Other: Musculoskelettal disorders patients

Musculoskelettal disorders patients take the MIQ-RS during about 40 minutes : about 20 minutes for the assessment of the right side and about 20 minutes for the left side

Diagnostic Test: Motor imagery Questionnaire - Revised Second (MIQ-RS)

Outcome Measures

Primary Outcome Measures

Motor imagery capacities on the affected side for CRPS group and musculoskelettal disorder group. [Day 1]
Taking the MIQ-RS for 1 side, during about 20 minutes The questionnaire includes 14 questions : 7 for kinesthesic motor imagery and 7 for visual motor imagery For less bias, the questionnaire was recorded in audio for each of the 14 questions on an online assessment. No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery a score between 49 and 73/98 have disturbed motor imagery capacities a score more than 74/98 have normal motor imagery capacities.

Secondary Outcome Measures

Motor imagery capacities between affected side and unaffected side [Day 1]
Taking the MIQ-RS for 1 side, during about 20 minutes The questionnaire includes 14 questions : 7 for kinesthesic motor imagery and 7 for visual motor imagery For less bias, the questionnaire was recorded in audio for each of the 14 questions on an online assessment. No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery a score between 49 and 73/98 have disturbed motor imagery capacities a score more than 74/98 have normal motor imagery capacities.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Patient with French healthcare affiliation
Adult patient (> 18 years old)
Patient with bachelor degree minimum
Patient practicing less than 150 minutes of moderate to intense physical activity per week

Specific Inclusion Criteria for CRPS group :

Patient followed in the Evaluation and Treatment pain center (University Hospital of Nimes)
Patient with secondary CRPS due to a traumatism or a surgery