New Diagnostic Markers In Dignosis Of Complicated Appendix
Sponsor
Sohag University (Other)
Overall Status
Recruiting
CT.gov ID
NCT06102239
Collaborator
(none)
50
1
6
8.4
Study Details
Study Description
Brief Summary
Most common cause of acute abdomen is acute appendicitis delay dignosis of acute appendicitis lead to complications as perforation this study examined efficacy of hyperbilirubinemia&hyponatremia as indicator of complicated appendicitis
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
50 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Diagnostic
Official Title:
New Diagnostic Markers In Dignosis Of Complicated Appendix
Actual Study Start Date
:
Oct 1, 2023
Anticipated Primary Completion Date
:
Mar 31, 2024
Anticipated Study Completion Date
:
Mar 31, 2024
Outcome Measures
Primary Outcome Measures
- Level of bilirubin in acute appendicitis [6 months]
- Level of sodium in acute appendicitis [6 months]
- Level of c-reactive proteins in acute appendicitis [6 months]
Eligibility Criteria
Criteria
Ages Eligible for Study:
10 Years
to 40 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
- all patient admitted for acute appendicitis underwent surgery and post operativly confirmed histopathology of acute appendicitis
Exclusion Criteria:
- patient with liver disease Liver transplantation Chronic alcoholism Congental biliary disease Pregnancy Appendicular neoplasm Hemolytic disease Hepatocellular carcinoma
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Sohag University hospital | Sohag | Egypt |
Sponsors and Collaborators
- Sohag University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med. 1986 May;15(5):557-64. doi: 10.1016/s0196-0644(86)80993-3.
- Kanumba ES, Mabula JB, Rambau P, Chalya PL. Modified Alvarado Scoring System as a diagnostic tool for acute appendicitis at Bugando Medical Centre, Mwanza, Tanzania. BMC Surg. 2011 Feb 17;11:4. doi: 10.1186/1471-2482-11-4.
- Kar S, Behera TK, Jena K, Sahoo AK. Hyperbilirubinemia as a Possible Predictor of Appendiceal Perforation in Acute Appendicitis: A Prospective Study. Cureus. 2022 Feb 2;14(2):e21851. doi: 10.7759/cureus.21851. eCollection 2022 Feb.
- Virmani S, Prabhu PS, Sundeep PT, Kumar V. Role of laboratory markers in predicting severity of acute appendicitis. Afr J Paediatr Surg. 2018 Jan-Mar;15(1):1-4. doi: 10.4103/ajps.AJPS_47_16.
Responsible Party:
Amr Mohamed Amin,
Residiant in general surgery department,
Sohag University
ClinicalTrials.gov Identifier:
NCT06102239
Other Study ID Numbers:
- Soh-Med-23-09-08Ms
First Posted:
Oct 26, 2023
Last Update Posted:
Oct 26, 2023
Last Verified:
Oct 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: