cASCA: Computerized Alcohol Screening for Children and Adolescents

Sponsor
Boston Children's Hospital (Other)
Overall Status
Withdrawn
CT.gov ID
NCT01539954
Collaborator
(none)
0
1
36
0

Study Details

Study Description

Brief Summary

The goal of this project is to develop a computerized screening program for primary care offices that is based on the NIAAA's Alcohol Screening Guide for Children and Adolescents and assess its psychometric properties among nine- to 18-yr-old primary care patients. There have been few studies of alcohol screening and brief intervention conducted among adolescents receiving primary medical care. This project will develop and validate a new computerized Alcohol Screening for Children and Adolescents (cASCA) system based on the two age-specific screening questions of the NIAAA Guide and includes the CRAFFT and AUDIT as secondary risk and problem assessments. The system will yield a provider report with the screening results, level of risk, and recommended brief advice, counseling, or referral strategies. The Specific Aims of this project are to: 1)Assess the sensitivity, specificity, positive and negative predictive values of the 'any drinking/number of drinking days' and 'friends' questions of the cASCA in identifying past-year use as determined by the Timeline Follow-Back Calendar (TLFB), and for identifying any problem use, abuse or dependence as determined by the AUDIT, CRAFFT and a structured psychiatric diagnostic interview (computerized DISC-IV, Youth Version) at baseline (criterion validity); 2)Assess the test-retest reliability of the cASCA in measuring drinking frequency categories and in classifying patients into Low, Medium and High risk categories; 3)Assess the predictive validity of the 'any drinking/number of drinking days' and 'friends' questions in predicting drinking, "binge" drinking, and any problem use, abuse or dependence at 12-mos follow-up; 4)Assess the degree to which the 'any drinking/number of drinking days' item of the cASCA predicts drug use risk as measured by the TLFB (any use and frequency), tobacco use as measured by the Hooked on Nicotine Checklist (screen for potential nicotine dependence), drug use disorders as measured by the Drug Abuse Screening Test for Adolescents, and the degree to which it predicts other mental health problems as measured by the Youth DISC Predictive Scales at baseline and 12-month follow-up; 5)Compare the psychometric properties of the cASCA across subgroups, including: age, gender, race/ethnicity, practice type, provider type, and patient risks (e.g., those with/without friends who drink); and explore the possible effects of the cASCA system on drinking at 3-, 6-, 9-, and 12-month follow-ups.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    0 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Cross-Sectional
    Official Title:
    Computerized Alcohol Screening for Children and Adolescents (cASCA) in Primary Care
    Study Start Date :
    Sep 1, 2012
    Anticipated Primary Completion Date :
    Sep 1, 2015
    Anticipated Study Completion Date :
    Sep 1, 2015

    Arms and Interventions

    Arm Intervention/Treatment
    Youth 9-18 years of age

    Outcome Measures

    Primary Outcome Measures

    1. Specificity and sensitivity of cASCA [Baseline]

      We will examine validity of the lifetime "any drinking" item by comparing participant responses on the c-ASCA to responses on the Brief Substance Use History (BSUH) questionnaire (lifetime use and age of initiation of use, if any).

    Secondary Outcome Measures

    1. Test-retest reliability of cASCA [baseline]

      We will calculate Cohen's kappas to evaluate 1-2 week test-retest agreement on c-ASCA responses

    2. Validity of "number of drinking days" item in c-ASCA [Baseline]

      For middle and high school-aged youth (12-18 yrs), we will examine validity of the c-ASCA past-year "number of drinking days" by computing the intra-class correlation coefficients (ICC) assessing agreement between the two continuous variables of total past-year number of days reported on c-ASCA and on the TLFB.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    9 Years to 18 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • nine- to 18-years old

    • arriving for non-emergent care

    • have an email address and internet access

    • provide informed assent/consent.

    Exclusion Criteria:
    • unable to read or understand English

    • living away at college at the time of the recruitment visit

    • not available for computer/telephone follow-ups

    • judged by the provider to be medically or emotionally unstable at time of visit.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Children's Hospital Boston Boston Massachusetts United States 02115

    Sponsors and Collaborators

    • Boston Children's Hospital

    Investigators

    • Principal Investigator: John R Knight, MD, Boston Children's Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Additional Information:

    Publications

    None provided.
    Responsible Party:
    John R Knight, MD, Associate Professor of Pediatrics, Harvard Medical School; Senior Associate in Medicine; Associate in Psychiatry, Director, Center for Adolescent Substance Abuse Research, Boston Children's Hospital, Boston Children's Hospital
    ClinicalTrials.gov Identifier:
    NCT01539954
    Other Study ID Numbers:
    • JK_NIAAA_02-12
    First Posted:
    Feb 28, 2012
    Last Update Posted:
    Oct 7, 2016
    Last Verified:
    Oct 1, 2016
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Keywords provided by John R Knight, MD, Associate Professor of Pediatrics, Harvard Medical School; Senior Associate in Medicine; Associate in Psychiatry, Director, Center for Adolescent Substance Abuse Research, Boston Children's Hospital, Boston Children's Hospital
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Oct 7, 2016