Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents

Sponsor

Wei XIA, PhD (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05958641

Collaborator

(none)

200

Enrollment

Location

4.5

Anticipated Duration (Months)

44.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old. This study intends to obtain the data related to the behavioral expression of addiction susceptibility genes, adverse childhood experience, cognition, resistance and the use of NPS in adolescents by questionnaire survey (sample size: 200), and then use logistic regression and machine learning to construct an early warning model.

Condition or Disease	Intervention/Treatment	Phase
Drug Addiction	Other: Questionnaires

Detailed Description

Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model on the use of the New Psychoactive Substances using for adolescents aged 14-35 years old. This study intends to conduct a questionnaire survey (sample size 200) to obtain data related to the behavioral expression of addiction susceptibility genes, childhood adversity experience, cognition, resistance and the use of NPS in adolescents from different regions and different populations. Through data analysis, this study aims to get the weight of different risk factors on NPS use, and then use logistic regression and machine learning to construct an early warning model, so as to screen out high-risk groups. At the same time, the expert group was consulted to establish a risk early warning system to provide a basis for intervention.

Study Design

Study Type:

Observational

Anticipated Enrollment :

200 participants

Observational Model:

Other

Time Perspective:

Cross-Sectional

Official Title:

Early Warning Model Construction on Cognition, Resistance and Using Risk of the New Psychoactive Substances in Adolescents Based on Behavioral Expression of Addiction Susceptibility Genes and Adverse Childhood Experience

Anticipated Study Start Date :

Jul 17, 2023

Anticipated Primary Completion Date :

Oct 31, 2023

Anticipated Study Completion Date :

Nov 30, 2023

Arms and Interventions

Arm	Intervention/Treatment
Investigation Team Questionnaires assessed adolescents aged 14-35 years old (including 14,25 years old) who agreed to participate in the study	Other: Questionnaires Participants will be asked to complete the questionnaire including general demographic information, the cognition, resistance and use of NPS as well as the behavioral expression of addiction susceptibility genes and adverse childhood experience.

Arm

Intervention/Treatment

Investigation Team

Questionnaires assessed adolescents aged 14-35 years old (including 14,25 years old) who agreed to participate in the study

Other: Questionnaires

Participants will be asked to complete the questionnaire including general demographic information, the cognition, resistance and use of NPS as well as the behavioral expression of addiction susceptibility genes and adverse childhood experience.

Outcome Measures

Primary Outcome Measures

the cognition of NPS [Baseline]
knowledge questionnaire of drug types and risk awareness of drug use will be investigated to know the degree of cognition to NPS
the resistance of NPS [Baseline]
the drug refusal self-efficacy scale and the drug use permissive attitude will be used to measure the the resistance of NPS
the use of NPS [Baseline]
there will be some questions to investigate the drug use conditions
Adverse Childhood Experience [Baseline]
the Chinese version of Adverse Childhood Experience Scale with 10 items will be used to measure the adverse childhood experience
hedonic hunger [Baseline]
the Power of Food Scale with 15 items will be used to measure hedonic hunger
sensation seeking personality [Baseline]
the Brief Sensation Seeking Scale for Chinese with 8 items will be used to measure sensation seeking personality
prosocial behavior [Baseline]
the Prosocial Tendencies Measure with 26 items will be used to measure prosocial behavior
externalizing behavior [Baseline]
17 items of aggressive behavior and 15 items of rule-breaking behavior from the Chinese Version of Achenbach Youth Self-Report-2001 Version will be used to measure adolescents' degree of externalizing behavior
sleep quality [Baseline]
the Pittsburgh Sleep Quality Index with 9 items will be used to measure adolescents' sleep quality

Eligibility Criteria

Criteria

Ages Eligible for Study:

14 Years to 35 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Adolescents aged 14-35 (including 14,35 years old)
Agree to participate in the studies

Exclusion Criteria:

Be diagnosed with psychological or mental illness
People that are unconscious, emotionally unstable, or unable to communicate normally
Patients with severe diseases