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The Construction of Precision Medicine in Chinese Medicine

Sponsor
China Medical University Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT04434924
Collaborator
(none)
600
Enrollment
1
Location
23.2
Actual Duration (Months)
25.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

"Precise medicine" is also called "personal medicine". With the development of big data database, genetic testing and artificial intelligence, the concept of precision medicine has been applied to the diagnosis, treatment and prevention of different diseases. Traditional Chinese medicine (TCM) has traditionally emphasis on personalized medicine, according to each person's body constitution, through discriminatory treatment and personalized treatment methods. Chinese medicine doctors collect patients' information to distinguish the type of TCM pattern, and then according to the different types of diagnosis of traditional Chinese medicine to decide of using herbs, acupuncture, massage and other treatment strategies. However, lacking of objective data of traditional Chinese medicine, the current research on precision medicine in Chinese medicine is still limited. The aim of this study is to establish a big database of traditional Chinese precision medicine, and use the patients with hypertension as the population to conduct research on precision medicine in Chinese medicine.This study will combine the TCM body constitutional questionnaire, tongue diagnosis, pulse diagnosis, Chinese medicine immunoassay and genetic testing. In addition, the information providing by the medical electronic medical record system of China Medical University Hospital will be connected, which include modern medical diagnosis, treatment, blood and biochemical analysis and imaging. We will combine the big data analysis and artificial intelligence interpretation technology to explore the correlation between different TCM syndrome types and gene variations in patients with hypertension and establish a database of TCM precision medicine. We will also conduct the education training and symposium to train TCM precision medical talents and promote public understanding of TCM precision medicine. This project will establish a database of traditional Chinese medicine precision medicine to provide the correlation between different TCM pattern types of patients with hypertension, the reaction to different herbal medicine, and gene mutation, and provide reference for TCM clinicians.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    600 participants
    Observational Model:
    Cohort
    Time Perspective:
    Cross-Sectional
    Official Title:
    The Construction of Precision Medicine in Chinese Medicine
    Actual Study Start Date :
    Jun 24, 2020
    Actual Primary Completion Date :
    May 31, 2022
    Actual Study Completion Date :
    May 31, 2022

    Outcome Measures

    Primary Outcome Measures

    1. The correlation between TCM body constitution and genetic variation [2 years]

      The correlation between TCM body constitution and genetic variation of patients with primary hypertension will be investigated.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    20 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    1. Primary hypertension

    2. Older than 20 year-old

    Exclusion Criteria:

    1. Past history of cancer

    2. Hemodialysis

    3. Hypertension caused by renal diseases or endocrine disorders

    4. Pregnancy

    5. Patients can not received investigation of body constitution, TCM tongue examination and pulse examination

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 China Medical University Hospital Taichung Taiwan 404

    Sponsors and Collaborators

    • China Medical University Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    China Medical University Hospital
    ClinicalTrials.gov Identifier:
    NCT04434924
    Other Study ID Numbers:
    • CMUH109-REC1-025
    First Posted:
    Jun 17, 2020
    Last Update Posted:
    Jul 20, 2022
    Last Verified:
    Jul 1, 2022
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by China Medical University Hospital
    Traditional Chinese precision medicine
    Chinese medicine immunoassay
    Body constitution
    genetic variation
    Additional relevant MeSH terms:
    Hypertension

    Study Results

    No Results Posted as of Jul 20, 2022