Corneal Barrier Function With Multi-Purpose Solutions
Sponsor
Southern California College of Optometry at Marshall B. Ketchum University (Other)
Overall Status
Completed
CT.gov ID
NCT00407238
Collaborator
Alcon Research (Industry)
25
1
3.9
6.3
Study Details
Study Description
Brief Summary
The purpose of this study is to evaluate the effect on epithelial barrier function of three emarketed multi-purpose solution applied to the human eye with hydrogel lenses as during normal regimen use.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
The purpose of this study is to evaluate the effect on epithelial barrier function of three emarketed multi-purpose solution applied to the human eye with hydrogel lenses as during normal regimen use.
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
25 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
Double
Primary Purpose:
Treatment
Official Title:
Comparison of Human Corneal Barrier Function With Three Marketed Multi-Purpose Solutions
Study Start Date
:
Nov 1, 2006
Actual Study Completion Date
:
Mar 1, 2007
Outcome Measures
Primary Outcome Measures
- Ratio of fluorescein dye penetration rate of test eye vs. control []
Secondary Outcome Measures
- Corneal fluorescein staining []
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
- Adapted daily soft contact lens wearers, at least 18 years of age, vision correctable to 20/40
Exclusion Criteria:
- Ocular or systemic allergies, abnormalities of the cornea, active ocular infection, prior keratorefractive surgery, use of ocular medications
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Southern California College of Optometry | Fullerton | California | United States | 92831 |
Sponsors and Collaborators
- Southern California College of Optometry at Marshall B. Ketchum University
- Alcon Research
Investigators
- Principal Investigator: Jerry R Paugh, OD, PhD, Southern California College of Optometry at Marshall B. Ketchum University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00407238
Other Study ID Numbers:
- 6-08
First Posted:
Dec 4, 2006
Last Update Posted:
Oct 23, 2007
Last Verified:
Oct 1, 2007
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