WARD: Continuous Monitoring of Vital Parameters for Early Detection of Clinical Deterioration in Hospitalized Patients
Study Details
Study Description
Brief Summary
For patients admitted to the medical ward, it is often difficult to predict if their clinical condition will deteriorate, however subtle changes in vital signs are usually present 8 to 24 hours before a life-threatening event such as respiratory failure leading to ICU admission, or unanticipated cardiac arrest. Such adverse trends in clinical observations can be missed, misinterpreted or not appreciated as urgent. New continuous and wearable 24/7 clinical vital parameter monitoring systems offer a unique possibility to identify clinical deterioration before patients condition progress beyond the point-of-no-return, where adverse events are inevitable. The WARD project aims to determine the correlation between cardiopulmonary micro events and clinical adverse events during the first four days after hospital admission.
| Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Outcome Measures
Primary Outcome Measures
- Serious desaturation [more than 10 minutes, within the first four days of acute admission]
SpO2 <85% in 10 consecutive minutes
Secondary Outcome Measures
- desaturation [more than 60 minutes, within the first four days of acute admission]
SpO2 <92% in 60 consecutive minutes
- tachycardia [one minute within the first four days of admission]
Heartrate >130/min
- bradycardia [one minute within the first four days of admission]
heartrate >41/min
- tachypnea [one minute within the first four days of admission]
Respiration rate >24/min
- bradypnea [one minute within the first four days of admission]
Respiration rate <9/min
- hypotension [one measurement within the first four days of admission]
Systolic blood pressure <90 mmHg
- hypertension [one measurement wihtin the first four days of admission]
systolic blood pressure >219 mmHg
Eligibility Criteria
Criteria
Inclusion Criteria:
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Adults >18 years
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Acute hospitalization or discharge from Intensive Care Unit (ICU) after an admission of at least 24 hours.
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Early Warning Score (EWS) ≥4 at least once from admission and until inclusion
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One of the following tentative diagnoses as the primary reason for admission: Pneumonia, Dyspnea, Acute myocardial infarction, heartfailure or sepsis
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Inclusion conversation possible within 12 hours of admission or discharge from ICU
Exclusion Criteria:
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Patients that cannot cooperate
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Patients that cannot give informed consent
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Patients with EWS≥4 that is not of presumed physical origin
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Patients with allergies to plaster or silicone
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Patients with pacemaker or ICD
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Patients with treatment limitations (no resuscitation or no admission to ICU)
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Patients with expected discharge within 24 hours
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Patients that have been included in the WARD-COPD study (H-18026653)
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- University Hospital Bispebjerg and Frederiksberg
- Technical University of Denmark
- Bispebjerg Hospital
- Rigshospitalet, Denmark
Investigators
- Study Chair: Christian Meyhoff, MD, PhD, Bispebjerg Hospital
- Principal Investigator: Katja Grønbæk, MD, Bispebjerg Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- H-19086056