Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Qingkepingchuan Granules Clinical Observation of Phlegm-Heat and Lung Depletion
Study Details
Study Description
Brief Summary
Through the clinical observation of Qingcheng Pingxian Granules in the treatment of acute exacerbation of chronic obstructive pulmonary disease (phlegm-heat lung syndrome), (1) to evaluate the safety of Qingcheng Pingxian Granules in the acute exacerbation of chronic obstructive pulmonary disease; (2) to observe the clinical efficacy of Qingcheng Pingxian Granules in the treatment of acute exacerbation of chronic obstructive pulmonary disease, to provide an effective medication and solution for the treatment of acute exacerbation of chronic obstructive pulmonary disease, and to provide data for the development of the further application of Qingcheng Pingxian Granules.
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: treatment group Qingkepingchuan Granules+Conventional basic therapy |
Drug: Qingkepingchuan Granules
Qingkepingchuan Granules,Take it three times a day with water after meals.
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Other: control subjects Conventional basic therapy |
Other: conventional treatment
Oxygen intake, selection of appropriate antibiotics based on lab results, and other treatments
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Outcome Measures
Primary Outcome Measures
- Chinese Medicine Symptoms Scale [Before the start of treatment, 1 week of treatment, 2 weeks of treatment, 1 month of follow-up]
Record changes in patients' TCM indicators。The scale includes cough, wheezing, shortness of breath, sputum volume, chest tightness, sputum colour, sputum quality, fever, thirst, irritability, constipation, tongue coating, and pulse. The first four items are rated 0-6, and the last nine items are rated 0-3, with higher ratings indicating poorer treatment outcomes.
- COPD assessment test [Before the start of treatment, 1 week of treatment, 2 weeks of treatment, 1 month of follow-up]
Record changes in the patient's condition
- breathlessness measurement using the modified British Medical Research Council [Before the start of treatment, 1 week of treatment, 2 weeks of treatment, 1 month of follow-up]
Record changes in the patient's condition
Secondary Outcome Measures
- 6-minute walking test [Before the start of treatment, 2 weeks of treatment]
Record changes in the patient's condition
Eligibility Criteria
Criteria
Inclusion Criteria:
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Meet the diagnostic criteria of AECOPD.
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Chinese medicine diagnosis is consistent with phlegm-heat and lung depletion evidence
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40 years old ≤ age ≤ 90 years old
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Patients who signed the informed consent form and volunteered to participate in the study
Exclusion Criteria:
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Combined with other primary lung diseases such as bronchial asthma, bronchiectasis, etc.
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Combination of serious cardiovascular, urinary, digestive, haematopoietic, endocrine metabolic system diseases, other psychiatric and neurological diseases.
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Pregnant or lactating patients.
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Allergic to the clinical trial drugs.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Beijing University of Chinese Medicine | Beijing | China |
Sponsors and Collaborators
- Zhang Zhijie
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- SY-1