"Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up

• Sponsor: Hillel Yaffe Medical Center (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT00960817
• Collaborator: (none)
• Location: 1
• Arms: 2

Study Details

Study Description

Brief Summary

The investigators will investigate patients undergoing coronary angiography with normal coronary but slow blood flow that was normalized after adenosine injection into the coronary artery. The investigators believe that they have small vessel coronary disease which is the initial presentation of coronary disease prior to anatomical narrowing. To alleviate this phenomenon the investigators intend to examine the long-term clinical response of these patients to treatment with dipyridamole, a well-known medication with almost no side-effects that increases the level of adenosine in the tissue.

Condition or Disease	Intervention/Treatment	Phase
Coronary Angiography	Drug: Statin, aspirin; Drug: Dipyridamole	Early Phase 1

Study Design

• Study Type: Interventional
• Official Title: "Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: 1. Routine treatment Control group	Drug: Statin, aspirin
Experimental: 2. Dipyridamole treatment Group that receives Dipyridamole treatment	Drug: Dipyridamole

Outcome Measures

Primary Outcome Measures

1. Alleviation of chest pain [Two years]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 80 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Patients undergoing coronary angiography and who have normal coronary artery with slow blood flow that normalized with adenosine injection into the coronary artery

Exclusion Criteria:

• Significant coronary disease

• Unstable patients

• Patients with known sensitivity to dipyridamole

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Hillel Yaffe Medical Center	Hadera		Israel	38100

Sponsors and Collaborators

• Hillel Yaffe Medical Center

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00960817
• Other Study ID Numbers: HYMC 02/2009
• First Posted: Aug 18, 2009
• Last Update Posted: Aug 18, 2009
• Last Verified: Aug 1, 2009

• Keywords provided by , ,: Normal coronary artery with slow blood flow
• Additional relevant MeSH terms: Aspirin; Dipyridamole

Study Results

No Results Posted as of Aug 18, 2009