CONCORDE: Comprehesive Assessment on diagnOstic and progNostic Performance of CORonary Physilogical inDices
Study Details
Study Description
Brief Summary
The objective of the Zhongshan Hospital CONCORDE Registry is to evaluate utility, diagnostic value, and clinical outcomes of coronary physilogical indices in an all-comers population of patients with suspected coronary artery disease referred to invasive coronary angiography in order to further inform patients and health care providersabout which technologies are most effective and efficient in the diagnosis and management of CAD.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Detailed Description
CONCORDE registry offers a comprehensive pressure and/or flow measurements, as well as angiography-derived functional assessment of coronary. Patient treatment was at the operator's discretion at the time of the invasive procedure. A standardized data collection sheet was used and data were extracted from electrical medical history according to standardized definition of patient's baseline characteristics, clinical outcomes, and physiologic data.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
All patients All patients referred to angiography and undergo assessment with coronary pressure sensor |
Other: coronary physiological indices
Resting distal coronary to aortic pressure ratio, Fractional flow reserve, Reseting full-cycle ratio, Coronary Flow Reserve, Microvascular resistance
|
Outcome Measures
Primary Outcome Measures
- Major adverse cardiac events [5 years]
Cumulative incidence of a composite of any death, any myocardial infarction, or any ischemia-driven revascularization
Secondary Outcome Measures
- Target vessel failure [5 years]
Cumulative incidence of a composite of cardiac death, target-vessel related myocardial infarction, or target-vessel revascularization
- Individual components of MACE and TVF [5 years]
Cumulative incidence of the individual components of MACE and TVF
Eligibility Criteria
Criteria
Inclusion Criteria:
-
suspected coronary artery disease
-
referred to invasive coronary angiography
Exclusion Criteria:
- hemodynamic instability
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Shanghai Zhongshan Hospital
Investigators
- Study Director: Chenguang Li, Shanghai Zhongshan Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- ZSCD2023001