VESALIUS-CV: Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

Sponsor

Amgen (Industry)

Overall Status

Active, not recruiting

CT.gov ID

NCT03872401

Collaborator

(none)

12,301

Enrollment

852

Locations

Arms

71.5

Anticipated Duration (Months)

14.4

Patients Per Site

0.2

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

Condition or Disease	Intervention/Treatment	Phase
Coronary Heart Disease (CHD)	Drug: Evolocumab Drug: Placebo	Phase 3

Study Design

Study Type:

Interventional

Actual Enrollment :

12301 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Primary Purpose:

Treatment

Official Title:

A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Impact of Evolocumab on Major Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

Actual Study Start Date :

Jun 11, 2019

Anticipated Primary Completion Date :

May 26, 2025

Anticipated Study Completion Date :

May 26, 2025

Arms and Interventions

Arm	Intervention/Treatment
Placebo Comparator: Placebo Participants will receive placebo subcutaneous injection once every 2 weeks (Q2W) for a minimum of 4 years.	Drug: Placebo Administered subcutaneously using an autoinjector pen.
Experimental: Evolocumab 140 mg Q2W Participants will receive 140 mg evolocumab by subcutaneous injection once every 2 weeks for a minimum of 4 years.	Drug: Evolocumab Administered subcutaneously using an autoinjector pen. Other Names: AMG 145 Repatha

Arm

Intervention/Treatment

Placebo Comparator: Placebo

Participants will receive placebo subcutaneous injection once every 2 weeks (Q2W) for a minimum of 4 years.

Drug: Placebo

Administered subcutaneously using an autoinjector pen.

Experimental: Evolocumab 140 mg Q2W

Participants will receive 140 mg evolocumab by subcutaneous injection once every 2 weeks for a minimum of 4 years.

Drug: Evolocumab

Administered subcutaneously using an autoinjector pen.

Other Names:

AMG 145

Repatha

Outcome Measures

Primary Outcome Measures

Time to Coronary Heart Disease Death, Myocardial Infarction, or Ischemic Stroke [From randomization; for approximately a median of 4.5 years]
Time to coronary heart disease (CHD) death, myocardial infarction (MI), or ischemic stroke, whichever occurs first.
Time to Coronary Heart Disease Death, Myocardial Infarction, Ischemic Stroke, or Any Ischemia-driven Arterial Sroke [From randomization; for approximately a median of 4.5 years]
Time to CHD death, MI, ischemic stroke, or any ischemia-driven arterial revascularization, whichever occurs first.

Secondary Outcome Measures

Time to MI, Ischemic Stroke, or Any Ischemia-driven Arterial Revascularization [From randomization; for approximately a median of 4.5 years]
Time to CHD Death, MI, or Any Ischemia-driven Arterial Revascularization [From randomization; for approximately a median of 4.5 years]
Time to Cardiovascular Death, MI, or Stroke [From randomization; for approximately a median of 4.5 years]
Time to Myocardial Infarction [From randomization; for approximately a median of 4.5 years]
Time to Any Ischemia-driven Arterial Revascularization [From randomization; for approximately a median of 4.5 years]
Time to CHD Death [From randomization; for approximately a median of 4.5 years]
Time to Cardiovascular Death [From randomization; for approximately a median of 4.5 years]
Time to All Cause of Death [From randomization; for approximately a median of 4.5 years]
Time to Ischemic Stroke [From randomization; for approximately a median of 4.5 years]

Eligibility Criteria

Criteria

Ages Eligible for Study:

50 Years to 79 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion criteria:

Age: Adult subjects ≥ 50 (men) or ≥ 55 (women) to ˂ 80 years of age (either sex) and meeting lipid criteria
Low-density lipoprotein cholesterol (LDL-C) ≥ 90 mg/dL (≥ 2.3 mmol/L) or non-high-density lipoprotein cholesterol (non-HDL) ≥ 120 mg/dL (≥ 3.1 mmol/L), or apolipoprotein B ≥ 80 mg/dL (≥ 1.56 µmol/L)
Evidence of at least one of the following at screening (without prior myocardial infarction or stroke):

Significant coronary artery disease (CAD) B. Significant atherosclerotic cerebrovascular disease C. Significant peripheral arterial disease D. Diabetes mellitus

At least 1 high-risk feature

Exclusion criteria

MI or stroke prior to randomization
Coronary artery bypass grafting (CABG) ˂ 3 months prior to screening
Estimated glomerular filtration rate (eGFR) ˂ 15 mL/min/1.73 m²
Uncontrolled or recurrent ventricular tachycardia in the absence of an implantable-cardioverter defibrillator.
Atrial fibrillation or atrial flutter not on anticoagulation therapy (vitamin K antagonist, heparin, low molecular weight heparin, fondaparinux,or non-Vitamin K antagonist oral anticoagulant)
Triglycerides ≥ 500 mg/dL (5.7 mmol/L) measured up to 3 months prior to screening. The most recent results must be used.
Last measured left-ventricular ejection fraction ˂ 30% or New York Heart Association (NYHA) Functional Class III/IV
Planned arterial revascularization

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	North Alabama Research Center LLC	Athens	Alabama	United States	35611
2	Cardiovascular Associates	Birmingham	Alabama	United States	35243
3	Heart Center Research LLC	Huntsville	Alabama	United States	35801
4	Mobile Heart Specialists PC	Mobile	Alabama	United States	36608
5	Arkansas Cardiology	Little Rock	Arkansas	United States	72205
6	Central Arkansas Veterans Healthcare System	Little Rock	Arkansas	United States	72205
7	Cardiovascular Research Foundation of Southern California	Beverly Hills	California	United States	90210
8	Westside Medical Associates of Los Angeles	Beverly Hills	California	United States	90211
9	West Coast Research LLC	Dublin	California	United States	94568
10	Desert Oasis Healthcare Medical Group	Palm Springs	California	United States	92262
11	Covigilant Research, LLC	Riverside	California	United States	92506
12	Sierra Clinical Research	Roseville	California	United States	95661
13	Center for Clinical Trials of Sacramento Inc	Sacramento	California	United States	95823
14	Harbor University of California Los Angeles Medical Center	Torrance	California	United States	90502
15	Optumcare Colorado Springs LLC	Colorado Springs	Colorado	United States	80906
16	University of Colorado Memorial Health System	Colorado Springs	Colorado	United States	80909
17	New West Physicians	Golden	Colorado	United States	80401
18	South Denver Cardiology Associates	Littleton	Colorado	United States	80120
19	Cardiology Associates of Fairfield County, PC	Stamford	Connecticut	United States	06905
20	Excel Medical Clinical Trials	Boca Raton	Florida	United States	33434
21	Bay Area Cardiology	Brandon	Florida	United States	33511
22	Nature Coast Clinical Research LLC	Crystal River	Florida	United States	34429
23	Daytona Heart Group	Daytona Beach	Florida	United States	32114
24	Cardiology Research Associates	Daytona Beach	Florida	United States	32117
25	Complete Health Research	DeLand	Florida	United States	32720
26	Cohen Medical Associates PA	Delray Beach	Florida	United States	33446
27	Jellinger and Lerman MD PA dba The Center for Diabetes and Endocrine Care	Fort Lauderdale	Florida	United States	33312
28	George E Platt MD	Green Cove Springs	Florida	United States	32043
29	Research Physicians Network Alliance	Hollywood	Florida	United States	33021
30	Baptist Health Research Institute	Jacksonville Beach	Florida	United States	32250
31	University of Florida and Shands Hospital	Jacksonville	Florida	United States	32209
32	Jacksonville Center for Clinical Research	Jacksonville	Florida	United States	32216
33	First Coast Cardiovascular Institute PA	Jacksonville	Florida	United States	32256
34	Gad Research Center	Miami	Florida	United States	33155
35	Cardiovascular Research Center of South Florida	Miami	Florida	United States	33173
36	Ocala Research Institute, Inc	Ocala	Florida	United States	34471
37	Cardiology Consultants	Pensacola	Florida	United States	32501
38	Charlotte Heart Group Research Center	Port Charlotte	Florida	United States	33952
39	Intercoastal Medical Group	Sarasota	Florida	United States	34232
40	Cardiovascular Center of Sarasota	Sarasota	Florida	United States	34239
41	Florida Cardiology Group	Winter Park	Florida	United States	32792
42	The Florida Lipid Institute	Winter Park	Florida	United States	32792
43	NSC Research	Johns Creek	Georgia	United States	30024
44	Kootenai Heart Clinics, LLC	Coeur d'Alene	Idaho	United States	83814
45	Northwest Heart Clinical Research LLC	Arlington Heights	Illinois	United States	60005
46	Deaconess Clinic	Evansville	Indiana	United States	47713
47	LaPorte County Institute for Clinical Research	Michigan City	Indiana	United States	46360
48	Midwest Cardiovascular Research Foundation	Davenport	Iowa	United States	52801
49	The University of Iowa College of Public Health	Iowa City	Iowa	United States	52242
50	MercyOne Iowa Heart Center	West Des Moines	Iowa	United States	50266
51	The University of Kansas Medical Center	Kansas City	Kansas	United States	66160-7601
52	Saint Elizabeth Covington	Covington	Kentucky	United States	41011
53	The Research Group of Lexington LLC	Lexington	Kentucky	United States	40503
54	Alexandria Cardiology Clinic	Alexandria	Louisiana	United States	71301
55	Grace Research LLC	Bossier City	Louisiana	United States	71111
56	Horizon Research Group of Opelousas LLC	Eunice	Louisiana	United States	70535
57	Louisiana Heart Center	Hammond	Louisiana	United States	70403
58	Barnum Medical Research	Natchitoches	Louisiana	United States	71457
59	Grace Research LLC	Shreveport	Louisiana	United States	71105
60	Louisiana Heart Center	Slidell	Louisiana	United States	70458
61	Northern Light Eastern Maine Medical Center	Bangor	Maine	United States	04401
62	Southern Maine Health Care	Biddeford	Maine	United States	04005
63	Maryland Cardiovascular Specialists	Baltimore	Maryland	United States	21229
64	Metropolitan Cardiovascular Consultants LLC	Beltsville	Maryland	United States	20705
65	TidalHealth Peninsula Regional, Inc	Salisbury	Maryland	United States	21804
66	Brigham and Womens Hospital	Boston	Massachusetts	United States	02215
67	Charles River Medical Associates	Framingham	Massachusetts	United States	01701
68	East Mountain Medical Associates, PC	Great Barrington	Massachusetts	United States	01230
69	Baystate Health Center	Springfield	Massachusetts	United States	01199
70	Ahmed Arif Medical Research Center LLC	Flint	Michigan	United States	48504
71	Healthy Heart Cardiology	Grand Rapids	Michigan	United States	49546
72	Rajendra H Mehta, MD, PC	Jackson	Michigan	United States	49201
73	Munson Medical Center	Traverse City	Michigan	United States	49684
74	Saint Marys Medical Center	Duluth	Minnesota	United States	55805
75	Minneapolis Heart Institute Foundation	Minneapolis	Minnesota	United States	55407
76	Saint Cloud Hospital	Saint Cloud	Minnesota	United States	56303
77	HealthEast Medical Research Institute	Saint Paul	Minnesota	United States	55102
78	Kansas City Veterans Affairs Medical Center	Kansas City	Missouri	United States	64128
79	Mercy Research	Saint Louis	Missouri	United States	63141
80	Great Falls Clinic LLP	Great Falls	Montana	United States	59405
81	Bryan Heart	Lincoln	Nebraska	United States	68506
82	Nebraska Western Iowa Health Care System	Omaha	Nebraska	United States	68105
83	Palm Research Center Inc	Las Vegas	Nevada	United States	89128
84	Virtua Health, Inc.	Voorhees	New Jersey	United States	08043
85	Healthwise Medical Associates	Brooklyn	New York	United States	11206
86	Trinity Medical Western New York, PC	Cheektowaga	New York	United States	14227
87	WMCHealth Heart and Vascular Institute Kingston Division of Cardiology	Kingston	New York	United States	12401
88	Northwell Health Physician Partners Cardiology	Manhasset	New York	United States	11030
89	North Shore Diabetes and Endocrine Associates	New Hyde Park	New York	United States	11042
90	Northwell Health Lenox Hill Heart and Vascular	New York	New York	United States	10022
91	Hudson Valley Cardiovascular Physicians PC	Poughkeepsie	New York	United States	12601
92	Saratoga Clinical Research, LLC	Saratoga Springs	New York	United States	12866
93	Division of Cardiovascular Research at Peconic Bay Medical Center	Southampton	New York	United States	11968
94	Asheville Cardiology Associates	Asheville	North Carolina	United States	28803
95	University of North Carolina at Chapel Hill	Chapel Hill	North Carolina	United States	27599
96	Novant Health Heart and Vascular Institute	Charlotte	North Carolina	United States	28204
97	Moses H Cone Memorial Hospital	Greensboro	North Carolina	United States	27401
98	Crossroads Clinical Research Inc	Mooresville	North Carolina	United States	28117
99	Piedmont Medical Group Research of Rocky Mount	Rocky Mount	North Carolina	United States	27804
100	PMG Research of Salisbury	Salisbury	North Carolina	United States	28144
101	Novant Health Forsyth Medical Center	Winston-Salem	North Carolina	United States	27103
102	Wake Forest University Health Sciences	Winston-Salem	North Carolina	United States	27157
103	Lillestol Research LLC	Fargo	North Dakota	United States	58104
104	The Christ Hospital	Cincinnati	Ohio	United States	45219
105	University Hospitals Cleveland Medical Center	Cleveland	Ohio	United States	44106
106	North Ohio Heart Center	Elyria	Ohio	United States	44035
107	Sanjay Vora Research LLC	Marion	Ohio	United States	43302
108	North Ohio Heart Center-Sandusky	Sandusky	Ohio	United States	44870
109	Heart House Research Foundation	Springfield	Ohio	United States	45504
110	Intend Research	Norman	Oklahoma	United States	73069
111	Oklahoma Heart Institute	Tulsa	Oklahoma	United States	74133
112	Oregon Health and Science University	Portland	Oregon	United States	97239
113	Capital Area Research LLC	Camp Hill	Pennsylvania	United States	17011
114	Geisinger Holy Spirit	Camp Hill	Pennsylvania	United States	17011
115	Doylestown Health Cardiology	Doylestown	Pennsylvania	United States	18901
116	Lycoming Internal Medicine Inc	Jersey Shore	Pennsylvania	United States	17740
117	Perelman Center for Advanced Medicine	Philadelphia	Pennsylvania	United States	19104
118	Cardiology Consultants of Philadelphia CCP	Philadelphia	Pennsylvania	United States	19107
119	University of Pittsburgh Medical Center	Pittsburgh	Pennsylvania	United States	15213
120	Miriam Hospital	Providence	Rhode Island	United States	02906
121	Pharmacorp Clinical Trials Inc	Charleston	South Carolina	United States	29412
122	Piedmont Research Partners	Fort Mill	South Carolina	United States	29707
123	Tribe Clinical Research LLC DBA Mountain View Clinical Research	Greenville	South Carolina	United States	29607
124	Main Street Physicians Care Waterway	Little River	South Carolina	United States	29566
125	The Diabetes Center	Murrells Inlet	South Carolina	United States	29576
126	Palmetto Clinical Research	Summerville	South Carolina	United States	29485
127	Monument Health Clinical Research	Rapid City	South Dakota	United States	57701
128	Parkway Cardiology Associates	Oak Ridge	Tennessee	United States	37830
129	Soltero Cardiovascular Research Center	Dallas	Texas	United States	75226
130	Southwest Family Medicine Associates	Dallas	Texas	United States	75235
131	Humble Cardiology Associates	Kingwood	Texas	United States	77339
132	Texas Cardiology Associates of Houston	Kingwood	Texas	United States	77339
133	Texas Institute for Kidney and Endocrine Disorders	Lufkin	Texas	United States	75904
134	Texas Institute of Cardiology	McKinney	Texas	United States	75071
135	Southern Endocrinology Associates PA	Mesquite	Texas	United States	75149
136	Permian Research Foundation	Odessa	Texas	United States	79761
137	South Texas Cardiovascular Consultants PLLC	San Antonio	Texas	United States	78201
138	Mercury Medical Conversions LTD	San Antonio	Texas	United States	78229
139	Northwest Houston Heart Center	Tomball	Texas	United States	77375
140	Alpine Research Organization	Farmington	Utah	United States	84025
141	Suffolk Multispecialty Research LLC	Suffolk	Virginia	United States	23435
142	Selma Medical Associates	Winchester	Virginia	United States	22601
143	Multicare Institute for Research and Innovation	Puyallup	Washington	United States	98372
144	Universal Research Group LLC	Tacoma	Washington	United States	98405
145	Aspirus Research Institute	Wausau	Wisconsin	United States	54401
146	Instituto de Investigaciones Clinicas Bahia Blanca	Bahia Blanca	Buenos Aires	Argentina	B8000FTD
147	Stat Research	Caba	Buenos Aires	Argentina	C1023AAB
148	Cinme - Centro de Investigaciones Metabolicas	Caba	Buenos Aires	Argentina	C1027AAP
149	Ciprec - Centro de Investigacion y Prevencion Cardiovascular	Caba	Buenos Aires	Argentina	C1119ACN
150	Consultorio Medico Dr Litvak Bruno	Caba	Buenos Aires	Argentina	C1406BOA
151	Centro de Especialidades Medicas - Cemedic	Caba	Buenos Aires	Argentina	C1407GTN
152	Centro Medico Laura Maffei	Caba	Buenos Aires	Argentina	C1425AGC
153	Cardiología Palermo	Caba	Buenos Aires	Argentina	C1425BNG
154	Cedic - Centro de Investigacion Clinica	Caba	Buenos Aires	Argentina	C1425DES
155	Centro Medico Dra De Salvo	Caba	Buenos Aires	Argentina	C1426ABP
156	Fundacion Respirar	Caba	Buenos Aires	Argentina	C1426ABP
157	Instituto de Investigaciones Metabolicas - Idim	Ciudad Autonoma de Buenos Aires	Buenos Aires	Argentina	C1012AAR
158	Hospital Universitario Fundacion Favaloro	Ciudad Autonoma de Buenos Aires	Buenos Aires	Argentina	C1093AAS
159	Icba - Instituto Cardiovascular de Buenos Aires	Ciudad Autonoma de Buenos Aires	Buenos Aires	Argentina	C1428ART
160	Glenny Corp SA	Ciudad Autonoma de Buenos Aires	Buenos Aires	Argentina	C1430CKE
161	Instituto de Investigaciones Clinicas Mar del Plata	Mar del Plata	Buenos Aires	Argentina	B7600FZN
162	Ciad - Consultorio Integral de Atencion al Diabetico	Moron	Buenos Aires	Argentina	B1708EPE
163	Dim Clinica Privada	Ramos Mejia	Buenos Aires	Argentina	B1704ETD
164	Instituto de Investigaciones Clinicas de San Nicolas	San Nicolas	Buenos Aires	Argentina	B2900DMH
165	Instituto de Investigaciones Clinicas Zarate	Zarate	Buenos Aires	Argentina	B2800DGH
166	Clinica Privada del Prado	Cordoba	Córdoba	Argentina	5000
167	Clinica Fusavim Privada SRL	Villa Maria	Córdoba	Argentina	X5900JKA
168	Sanatorio Santa Rosa Srl	Santa Rosa	La Pampa	Argentina	6300
169	Instituto de Investigaciones Clínicas Rosario-Sanatorio Delta	Rosario	Santa Fe	Argentina	2000
170	Sanatorio Plaza	Rosario	Santa Fe	Argentina	2000
171	Centro Modelo de Cardiologia	San Miguel de Tucuman	Tucuman	Argentina	4000
172	Clinical Mayo de Urgencias Medicas Cruz Blanca SRL	San Miguel de Tucuman	Tucuman	Argentina	4000
173	Instituto de Cardiologia de Corrientes Juana Francisca Cabral	Corrientes		Argentina	W3400AMZ
174	Instituto Medico DAMIC - Fundacion Rusculleda	Córdoba		Argentina	X5003DCE
175	Cordis Sa	Salta		Argentina	A4400ANW
176	Clinica El Castano	San Juan		Argentina	J5400ARW
177	Instituto Cardiovascular San Luis	San Luis		Argentina	D5702JRS
178	Centro de Investigaciones Clinicas del Litoral	Santa Fe		Argentina	S3000FWO
179	Canberra Hospital	Garran	Australian Capital Territory	Australia	2605
180	Royal Prince Alfred Hospital	Camperdown	New South Wales	Australia	2050
181	Liverpool Hospital	Liverpool	New South Wales	Australia	2170
182	Australian Clinical Research Network	Maroubra	New South Wales	Australia	2035
183	Heartcare Partners	Auchenflower	Queensland	Australia	4066
184	Bundaberg Cardiology	Bundaberg	Queensland	Australia	4670
185	Holdsworth House Medical Brisbane	Fortitude Valley	Queensland	Australia	4006
186	Core Research Group Pty Ltd	Milton	Queensland	Australia	4064
187	Heart and Vascular Research	Adelaide	South Australia	Australia	5000
188	Royal Adelaide Hospital	Adelaide	South Australia	Australia	5000
189	SA Heart	Ashford	South Australia	Australia	5035
190	Adelaide Cardiology Practice - Leabrook Clinic	Leabrook	South Australia	Australia	5068
191	Royal Hobart Hospital	Hobart	Tasmania	Australia	7000
192	HeartCare Victoria - Berwick	Berwick	Victoria	Australia	3806
193	Monash Medical Centre	Clayton	Victoria	Australia	3168
194	The Cardiologists Proprietary Limited	Epping	Victoria	Australia	3076
195	Barwon Health Geelong Hospital	Geelong	Victoria	Australia	3220
196	GenesisCare Ringwood	Ringwood	Victoria	Australia	3134
197	Curtin University Centre of Clinical Research and Education	Bentley	Western Australia	Australia	6102
198	HeartCare Western Australia - Joondalup	Joondalup	Western Australia	Australia	5068
199	Fiona Stanley Hospital	Murdoch	Western Australia	Australia	6150
200	Dr Heart Pty Ltd	Woolloongabba		Australia	4102
201	Landeskrankenhaus Feldkirch	Feldkirch		Austria	6800
202	Medizinische Universitaet Graz	Graz		Austria	8036
203	Medizinische Universitaet Innsbruck	Innsbruck		Austria	6020
204	Klinikum Klagenfurt am Woerthersee	Klagenfurt		Austria	9020
205	Ordensklinikum Linz Barmherzige Schwestern	Linz		Austria	4010
206	Klinik Landstrasse	Wien		Austria	1030
207	Zentrum fuer klinische Studien - Dr Hanusch GmbH	Wien		Austria	1060
208	Universitaetsklinikum Allgemeines Krankenhaus Wien	Wien		Austria	1090
209	Klinik Hietzing	Wien		Austria	1130
210	Klinik Ottakring	Wien		Austria	1160
211	Algemeen Stedelijk Ziekenhuis Aalst	Aalst		Belgium	9300
212	Onze Lieve Vrouw Ziekenhuis - campus Aalst	Aalst		Belgium	9300
213	Ziekenhuis Netwerk Antwerpen Middelheim	Antwerpen		Belgium	2020
214	Ziekenhuis Netwerk Antwerpen Stuivenberg	Antwerpen		Belgium	2060
215	Universite Catholique de Louvain Cliniques Universitaires Saint Luc	Bruxelles		Belgium	1200
216	AZ Sint Blasius	Dendermonde		Belgium	9200
217	Algemeen Ziekenhuis Sint Lucas	Gent		Belgium	9000
218	Medif sprl	Gozee		Belgium	6534
219	Dokter Mortelmans bvba	Ham		Belgium	3945
220	Jessa Ziekenhuis - Campus Virga Jesse	Hasselt		Belgium	3500
221	Universitair Ziekenhuis Leuven - Campus Gasthuisberg	Leuven		Belgium	3000
222	Medilink sprl	Linkebeek		Belgium	1630
223	Centre Hospitalier Universitair Ambroise Pare	Mons		Belgium	7000
224	Maria Ziekenhuis Noord-Limburg	Pelt		Belgium	3900
225	Testumed vzw	Tessenderlo		Belgium	3980
226	Centro de Pesquisas em Diabetes e Doencas Endocrino Metabolicas	Fortaleza	Ceará	Brazil	60430-350
227	Centro de Pesquisa Clinica do Brasil	Brasília	Distrito Federal	Brazil	71625-175
228	Cardresearch Cardiologia Assistencial de Pesquisa	Belo Horizonte	Minas Gerais	Brazil	30150-240
229	Fundaçao Hospitalar Sao Francisco de Assis	Belo Horizonte	Minas Gerais	Brazil	31110-580
230	Eurolatino Pesquisas Medicas	Uberlandia	Minas Gerais	Brazil	38411-186
231	Sociedade Hospitalar Angelina Caron	Campina Grande do Sul	Paraná	Brazil	83430-000
232	Quanta Diagnosticos e Terapia	Curitiba	Paraná	Brazil	80045-170
233	Puc Trials - Núcleo de Pesquisa Clínica da Escola de Medicina da Pucpr/Epicenter	Curitiba	Paraná	Brazil	80230-130
234	Nucleo de Pesquisa Clinica	Curitiba	Paraná	Brazil	80730-150
235	Núcleo de Pesquisa em Cirurgia Vascular	Porto Alegre	Rio Grande Do Sul	Brazil	90035-903
236	Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul	Porto Alegre	Rio Grande Do Sul	Brazil	90610-000
237	Hospital Nossa Senhora da Conceicao	Porto Alegre	Rio Grande Do Sul	Brazil	91350-200
238	AngioCor Blumenau	Blumenau	Santa Catarina	Brazil	89020-430
239	Centro Especializado em Cardiologia	Campinas	São Paulo	Brazil	13010-001
240	Instituto de Pesquisa Clinica de Campinas	Campinas	São Paulo	Brazil	13060-080
241	Instituto do Coracao de Marilia	Marilia	São Paulo	Brazil	17515-000
242	Centro de Pesquisas Clinicas Cpclin	Sao Paulo	São Paulo	Brazil	01228-200
243	Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto	São José do Rio Preto	São Paulo	Brazil	15090-000
244	IBPClin Instituto Brasil de Pesquisa Clinica	Rio de Janeiro		Brazil	20241-180
245	Instituto do Coracao do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo	São Paulo		Brazil	05403-000
246	Ambulatory for special outpatient medical aid in Cardiology-Private Practice Dr Elena Dotcheva EOOD	Burgas		Bulgaria	8000
247	Multiprofile Hospital for Active Treatment - Haskovo AD	Haskovo		Bulgaria	6300
248	Specialty Hospital for Active treatment in Cardiology Sveti Georgi - Pernik OOD	Pernik		Bulgaria	2300
249	Medical Center Medconsult OOD	Pleven		Bulgaria	5800
250	University Multiprofile Hospital for Active Treatment Dr Georgi Stranski EAD	Pleven		Bulgaria	5800
251	University Multiprofile Hospital for Active Treatment Sveti Georgi EAD	Plovdiv		Bulgaria	4001
252	Multiprofile Hospital for Active Treatment- Medical Complex- Sveti Ivan Rilski EOOD	Plovdiv		Bulgaria	4003
253	Fifth Multiprofile Hospital for Active Treatment - Sofia EAD	Sofia		Bulgaria	1233
254	National Multiprofile Transport Hospital Tzar Boris III	Sofia		Bulgaria	1233
255	Medical Center for Specialized Medical Care of Cardiovascular Diseases OOD	Sofia		Bulgaria	1309
256	Acibadem City Clinic Multiprofile Hospital for Active Treatment Tokuda EAD	Sofia		Bulgaria	1407
257	Medical Center Excelsior OOD	Sofia		Bulgaria	1407
258	University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna - ISUL EAD	Sofia		Bulgaria	1527
259	University Multiprofile Hospital for Active Treatment and Emergency Medicine N I Pirogov EAD	Sofia		Bulgaria	1606
260	Diagnostic-Consultative Center Convex EOOD	Sofia		Bulgaria	1680
261	Medical Center Kalimat EOOD	Sofia		Bulgaria	1680
262	Multiprofile Hospital for Active Treatment Sveta Anna Sofia AD	Sofia		Bulgaria	1750
263	Medical Center Orpheus OOD	Stara Zagora		Bulgaria	6000
264	Multiprofile Regional Hospital for Active Treatment Dr Stefan Cherkezov AD	Veliko Tarnovo		Bulgaria	5002
265	LMC Clinical Research Incorporated	Calgary	Alberta	Canada	T2H 2G4
266	SMH Cardiology Clinical Trials Incorporated	Surrey	British Columbia	Canada	V3V 0C6
267	Dr T G Elliott Incorporated - BC Diabetes	Vancouver	British Columbia	Canada	V5Y 3W2
268	Winnipeg Clinic	Winnipeg	Manitoba	Canada	R3C 0N2
269	G A Research Associates Limited	Moncton	New Brunswick	Canada	E1G 1A7
270	Commonwealth Medical Clinic	Mount Pearl	Newfoundland and Labrador	Canada	A1N 1W7
271	Queen Elizabeth II Health Sciences Centre, Halifax Infirmary	Halifax	Nova Scotia	Canada	B3H 3A7
272	Heart Health Institute	Ajax	Ontario	Canada	L1Z 0B1
273	LMC Clinical Research Incorporated	Barrie	Ontario	Canada	L4N 7L3
274	LMC Clinical Research Incorporated	Brampton	Ontario	Canada	L6S 0C6
275	Brampton Clinical Trials	Brampton	Ontario	Canada	L6Z 4N5
276	LMC Clinical Research Incorporated Thornhill	Concord	Ontario	Canada	L4K 4M2
277	LMC Clinical Research Incorporated	Etobicoke	Ontario	Canada	M9R 4E1
278	Hamilton Health Sciences Hamilton General Hospital	Hamilton	Ontario	Canada	L8L 2X2
279	Western Centre for Public Health and Family Medicine - Western University	London	Ontario	Canada	N6G 2M1
280	My Endo Diabetes and Endocrinology Center	Markham	Ontario	Canada	L3P 7P2
281	LMC Clinical Research Incorporated	Nepean	Ontario	Canada	K2J 0V2
282	Partners in Advanced Cardiac Evaluation	Newmarket	Ontario	Canada	L3Y 2P6
283	SKDS Research Incorporated	Newmarket	Ontario	Canada	L3Y 5G8
284	Oakville Cardiovascular Research	Oakville	Ontario	Canada	L6K 3W7
285	Dr James Cha	Oshawa	Ontario	Canada	L1J 2K1
286	Kawartha Cardiology Clinical Trials	Peterborough	Ontario	Canada	K9J 0B2
287	Bluewater Clinical Research Group Incorporated	Sarnia	Ontario	Canada	N7T 4X3
288	Heart Health Institute Research Incorporated	Scarborough	Ontario	Canada	M1B 4Z8
289	Corcare Cardiovascular Research	Scarborough	Ontario	Canada	M1B 5N1
290	Womens College Hospital	Toronto	Ontario	Canada	M5S 1B2
291	North York Diagnostic and Cardiac Centre	Toronto	Ontario	Canada	M6B 3H7
292	Office of Dr Louis Yao	Weston	Ontario	Canada	M9N 1W4
293	Ecogene-21	Chicoutimi	Quebec	Canada	G7H 7K9
294	Manna Research Incorporated	Levis	Quebec	Canada	G6W 0M5
295	Clinique Sante Cardio MC	Montreal	Quebec	Canada	H1T 3Y7
296	Institut de recherches cliniques de Montreal	Montreal	Quebec	Canada	H2W 1R7
297	McGill University Health Centre - Montreal General Hospital	Montreal	Quebec	Canada	H3G 1A4
298	Applied Medical Informatics Research Incorporated	Montreal	Quebec	Canada	H4A 3T2
299	Centre intégré de santé et de services sociaux (CISSS) des Laurentides - Unité de recherche clini	St Jerome	Quebec	Canada	J7Z 5T3
300	Clinique des Maladies Lipidiques de Quebec Incorporated	Quebec		Canada	G1V 4W2
301	MUDr Igor Karen	Benatky nad Jizerou		Czechia	294 71
302	Jessenia as, Nemocnice Beroun	Beroun		Czechia	266 01
303	Medicentrum Beroun sro	Beroun		Czechia	266 01
304	Medicus Services sro	Brandys nad Labem		Czechia	250 01
305	Amkardia sro	Brno		Czechia	602 00
306	CCR Brno sro	Brno		Czechia	602 00
307	Centrum pro zdravi sro	Brno		Czechia	603 00
308	Kardiologicka ambulance Brno sro	Brno		Czechia	612 00
309	Fakultni nemocnice Brno	Brno		Czechia	625 00
310	Vojenska nemocnice Brno	Brno		Czechia	636 00
311	prof MUDr Lubomir Elbl, CSc, Kardiologicka ambulance	Brno		Czechia	638 00
312	Edumed sro, Kardiologicka ambulance	Broumov		Czechia	550 01
313	Cevni centrum Ceske Budejovice sro	Ceske Budejovice		Czechia	370 11
314	Dika centrum sro	Havirov - Mesto		Czechia	736 01
315	Clinical Trial Center Hodonin sro	Hodonin		Czechia	695 01
316	Kardio Holesov sro	Holesov		Czechia	769 01
317	MUDr Ladislava Harrerova, kardiologicka ordinace	Hradec Kralove		Czechia	500 02
318	Karlovarska krajska nemocnice	Karlovy Vary		Czechia	360 01
319	Oblastni nemocnice Kladno as	Kladno		Czechia	272 59
320	Kardio Michal Cepelak sro	Klatovy IV		Czechia	339 01
321	Oblastni nemocnice Kolin as	Kolin III		Czechia	280 02
322	Krajska nemocnice Liberec as	Liberec		Czechia	460 63
323	KardioBusak sro	Louny		Czechia	440 01
324	Kardio Pudich s.r.o.	Ludgerovice		Czechia	747 14
325	Vseobecna intermi ambulance sro	Milevsko		Czechia	399 01
326	MUDr Zbynek Kosek, kardiologicka ambulance sro	Mlada Boleslav		Czechia	293 01
327	Pozdisek sro, Kardiologicka ambulance	Mohelnice		Czechia	789 85
328	Benedor sro - Kardiologicka, cevni a interni ambulance	Ostrava - Poruba		Czechia	708 00
329	Kardiologicka a angiologicka ambulance	Ostrava-Dubina		Czechia	700 30
330	CCR Ostrava sro	Ostrava		Czechia	702 00
331	Mestska nemocnice Ostrava	Ostrava		Czechia	728 80
332	Center for Clinical Research Pardubice, sro	Pardubice		Czechia	530 02
333	Nemocnice Pardubickeho kraje as	Pardubice		Czechia	532 03
334	Kardiologie v sadech sro	Plzen 1		Czechia	310 01
335	Kardiologie Cor sro	Praha 10 - Zabehlice		Czechia	106 00
336	Ordinace pro choroby srdce a cev	Praha 10		Czechia	101 00
337	Diabet2 sro	Praha 1		Czechia	110 00
338	Vseobecna fakultni nemocnice v Praze	Praha 2		Czechia	128 08
339	CCR Prague sro	Praha 3		Czechia	130 00
340	Thomayerova nemocnice	Praha 4		Czechia	140 59
341	Milan Kvapil sro	Praha 4		Czechia	149 00
342	Kardiologicke centrum MUDr Janky Skrobakove sro	Praha 5 - Smichov		Czechia	150 00
343	Fakultni nemocnice v Motole	Praha 5		Czechia	150 06
344	Interni a kardiologicka ordinace	Praha 5		Czechia	158 00
345	Endokrinologie Cerny Most sro	Praha 9		Czechia	198 00
346	Kardio Vaclavik sro, Interni a kardiologicka ambulance	Prerov		Czechia	750 02
347	Vestra Clinics sro	Rychnov nad Kneznou		Czechia	516 01
348	Nemocnice Pardubickeho kraje as, Svitavska nemocnice	Svitavy		Czechia	568 25
349	AeskuLab ks, Lipidova poradna	Teplice		Czechia	415 01
350	Nemocnice Podlesi as	Trinec		Czechia	739 61
351	Clinical Trials Service sro	Uherske Hradiste		Czechia	686 01
352	Interni ambulance	Uherske Hradiste		Czechia	686 01
353	Lekarsky dum Ormiga	Zlin		Czechia	760 01
354	KIGE sro	Znojmo		Czechia	669 02
355	Aalborg Hospital	Aalborg		Denmark	9000
356	Center for Clinical and Basic Research Aalborg	Aalborg		Denmark	9000
357	Aarhus Universitetshospital	Aarhus N		Denmark	8200
358	Centre for Clinical and Basic Research Ballerup	Ballerup		Denmark	2750
359	Sydvestjysk Sygehus	Esbjerg		Denmark	6700
360	Sanos Clinic	Herlev		Denmark	2730
361	Steno Diabetes Center	Herlev		Denmark	2730
362	Regionhospitalet Herning	Herning		Denmark	7400
363	Hillerod Hospital	Hillerod		Denmark	3400
364	Rigshospitalet Kobenhavn	Kobenhavn O		Denmark	2100
365	Amager Hospital	Kobenhavn S		Denmark	2300
366	Kolding Sygehus	Kolding		Denmark	6000
367	Regionshospitalet Silkeborg	Silkeborg		Denmark	8600
368	Svendborg Sygehus	Svendborg		Denmark	5700
369	Center for Clinical and Basic Research Vejle	Vejle		Denmark	7100
370	Regionshospitalet Viborg	Viborg		Denmark	8800
371	Liina Viitas OU	Parnu		Estonia	80014
372	Center for Clinical and Basic Research Tallinn	Tallinn		Estonia	10128
373	Dr Arvo Rosenthal LLC	Tallinn		Estonia	13419
374	North Estonia Medical Centre Foundation	Tallinn		Estonia	13419
375	Helsinki University Central Hospital	Helsinki		Finland	00029
376	GERI-MED Oy	Helsinki		Finland	00100
377	Pohjois-Karjalan keskussairaala	Joensuu		Finland	80210
378	Terveystalo Jyvaskyla	Jyvaskyla		Finland	40100
379	Studycor Oy	Jyvaskyla		Finland	40620
380	Satucon Oy/Kuopion tyoterveys	Kuopio		Finland	70100
381	University of Eastern Finland	Kuopio		Finland	70210
382	Oulu University Hospital	Oulu		Finland	90029
383	Oulu University Hospital	Oulu		Finland	90220
384	Tampere University Hospital	Tampere		Finland	33520
385	Terveystalo Pulssi	Turku		Finland	20100
386	Centre Hospitalier Universitaire Amiens - Hopital Sud	Amiens Cedex 1		France	80054
387	Hospices Civils de Lyon Groupement Hospitalier Est, Hopital Louis Pradel	Bron		France	69677
388	Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre	Caen Cedex 9		France	14033
389	Centre Hospitalier Sud Francilien	Corbeil Essonnes		France	91106
390	Centre Hospitalier Universitaire de Dijon - Hopital Francois Mitterrand	Dijon		France	21079
391	Groupement Hospitalier Mutualiste	Grenoble		France	38000
392	Centre Hospitalier Universitaire de Grenoble - Hopital Nord Michallon	Grenoble		France	38700
393	Centre Hospitalier de Versailles - Hopital Andre Mignot	Le Chesnay		France	78150
394	Hopital Louis Pasteur	Le Coudray		France	28630
395	Centre Hospitalier Régional Universitaire de Lille - Institut Coeur Poumon	Lille		France	59037
396	Centre Hospitalier Universitaire de Lyon - Hopital Edouard Herriot	Lyon Cédex 3		France	69437
397	Centre Hospitalier Universitaire de Marseille - Hôpital de la Timone	Marseille cedex 05		France	13385
398	Hopital Saint-Joseph	Marseille Cedex 08		France	13285
399	Centre Hospitalier Regional Universitaire de Montpellier - Hopital Arnaud de Villeneuve	Montpellier cedex 05		France	34295
400	Centre Hospitalier Universitaire de Nantes - Hopital Guillaume et Rene Laennec	Nantes Cedex 1		France	44093
401	Centre Hospitalier Universitaire de Nice - Hopital Pasteur	Nice Cedex 1		France	06002
402	Centre Hospitalier Universitaire de Nimes	Nimes		France	30029
403	Hopital Saint Antoine	Paris		France	75012
404	Hopital Pitie-Salpetriere	Paris		France	75013
405	Hopital Europeen Georges Pompidou	Paris		France	75015
406	Hopital Bichat Claude Bernard	Paris		France	75018
407	Centre Hospitalier de Pau - Hopital Francois Mitterrand	Pau		France	64000
408	Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou	Rennes		France	35033
409	Clinique Saint Hilaire	Rouen		France	76000
410	Clinique Pasteur	Toulouse Cedex 3		France	31076
411	Centre Hospitalier Universitaire de Toulouse - Hopital Rangueil	Toulouse Cedex 9		France	31059
412	Polyclinique Vauban	Valenciennes		France	59300
413	Universitaets-Herzzentrum Freiburg - Bad Krozingen	Bad Krozingen		Germany	79189
414	Kerckhoff-Klinik Forschungs GmbH	Bad Neuheim		Germany	61231
415	Klinische Forschung Berlin GbR	Berlin		Germany	10787
416	Charite Universitätsmedizin Berlin, Charité Campus Virchow-Klinikum	Berlin		Germany	13353
417	Kardiologisch - Angiologische Praxis - Herzzentrum Bremen	Bremen		Germany	28277
418	Sankt-Johannes-Hospital	Dortmund		Germany	44137
419	Cardiologicum Dresden und Pirna	Dresden		Germany	01277
420	Diabetologische Gemeinschaftspraxis Dr Schaper und Dr Faulmann	Dresden		Germany	01279
421	Universitaetsklinikum Carl Gustav Carus, Medizinische Klinik und Poliklinik III	Dresden		Germany	01307
422	Klinikum und Fachbereich Medizin Johann Wolfgang Goethe-Universität Frankfurt am Main	Frankfurt am Main		Germany	60590
423	Clin Phenomics GmbH Co KG	Frankfurt am Main		Germany	60596
424	Medizinisches Versorgungszentrum im Altstadt-Carree Fulda	Fulda		Germany	36037
425	Cardiologicum Hamburg	Hamburg		Germany	22041
426	Universitätsklinikum Heidelberg	Heidelberg		Germany	69120
427	Ambulantes Herzzentrum Kassel	Kassel		Germany	34121
428	Universitätsklinikum Leipzig	Leipzig		Germany	4103
429	Otto von Guericke Universität Magdeburg	Magdeburg		Germany	39120
430	Johannes Gutenberg Universitaet Mainz	Mainz		Germany	55131
431	Universitätsklinikum Mannheim	Mannheim		Germany	68167
432	Praxis Doktor Jens Taggeselle	Markleeberg		Germany	04416
433	Deutsches Herzzentrum München des Freistaates Bayern	München		Germany	80636
434	Herz Gefaess Zentrum Nymphenburg	München		Germany	80638
435	Universitaetsklinikum Muenster	Münster		Germany	48149
436	Kardiologische Gemeinschaftspraxis Papenburg	Papenburg		Germany	26871
437	Klinikum Ernst von Bergmann gGmbH	Potsdam		Germany	14467
438	Universitätsklinikum Regensburg	Regensburg		Germany	93053
439	CardioConsil GmbH	Rostock		Germany	18059
440	I Medizinische Klinik Gesundheitsverbund Landkreis Konstanz	Singen		Germany	78224
441	Universitätsklinikum Ulm	Ulm		Germany	89081
442	Nephrologisches Zentrum Villingen-Schwenningen	Villingen-Schwenningen		Germany	78052
443	Forschungszentrum Ruhr	Witten		Germany	58455
444	General Hospital of Athens Evaggelismos	Athens		Greece	10676
445	Athens Naval Hospital	Athens		Greece	11521
446	General Hospital of Athens Georgios Gennimatas	Athens		Greece	11527
447	General Hospital of Athens Ippokrateio	Athens		Greece	11527
448	General Hospital of Athens Laiko	Athens		Greece	11527
449	Alexandra Hospital	Athens		Greece	11528
450	Konstantopoulio - Agia Olga Hospital of Nea Ionia	Athens		Greece	14233
451	Hygeia Hospital	Athens		Greece	15123
452	University Hospital of Heraklion	Heraklion		Greece	71110
453	University Hospital of Ioannina	Ioannina		Greece	45500
454	University Hospital of Larissa	Larissa		Greece	41110
455	Ahepa University Hospital	Thessaloniki		Greece	54636
456	General Hospital of Thessaloniki Ahepa	Thessaloniki		Greece	54636
457	Papageorgiou General Hospital of Thessaloniki	Thessaloniki		Greece	56403
458	Interbalkan Medical Center	Thessaloniki		Greece	57001
459	Lausmed Kft	Baja		Hungary	6500
460	Allami Szivkorhaz Balatonfured	Balatonfured		Hungary	8230
461	Balatonmariafurdo Kozseg Onkormanyzatanak Haziorvosi Rendeloje	Balatonkeresztur		Hungary	8647
462	Med-Edu Bt	Balloszog		Hungary	6035
463	Dr Lakatos Ferenc Private Cardiology Practice	Bekescsaba		Hungary	5600
464	Grof Tisza Istvan Korhaz	Berettyoujfalu		Hungary	4100
465	Betegapolo Irgalmas Rend - Budai Irgalmasrendi Korhaz	Budapest		Hungary	1023
466	Clinexpert Kft	Budapest		Hungary	1033
467	Obudai Egeszsegugyi Centrum Kft	Budapest		Hungary	1036
468	Semmelweis Egyetem Varosmajori Sziv- es Ergyogyaszati Klinika	Budapest		Hungary	1085
469	Gottsegen Gyorgy Orszagos Kardiologiai Intezet	Budapest		Hungary	1096
470	Bajcsy-Zsilinszky Korhaz es Rendelointezet	Budapest		Hungary	1106
471	Semmelweis Egyetem	Budapest		Hungary	1122
472	Magyar Honvedseg Egeszsegugyi Kozpont	Budapest		Hungary	1134
473	Uzsoki Utcai Korhaz	Budapest		Hungary	1145
474	Zugloi Egeszsegugyi Szolgalat	Budapest		Hungary	1148
475	Jahn Ferenc Del-pesti Korhaz es Rendelointezet	Budapest		Hungary	1204
476	Debreceni Egyetem Klinikai Kozpont	Debrecen		Hungary	4032
477	Markhot Ferenc Oktatokorhaz es Rendelointezet	Eger		Hungary	3300
478	Erzsebet Gondozohaz	Godollo		Hungary	2100
479	Bugat Pal Korhaz	Gyongyos		Hungary	3200
480	Pharma4 Trial Kft	Gyongyos		Hungary	3200
481	Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz	Gyula		Hungary	5700
482	BKS Research Kft	Hatvan		Hungary	3000
483	Bacs-Kiskun Megyei Korhaz Szegedi Tudomanyegyetem Altalanos Orvostudomanyi Kar Oktato Korhaza	Kalocsa		Hungary	6300
484	Selye Janos Korhaz	Komarom		Hungary	2921
485	Borsod-Abauj-Zemplen Megyei Kozponti Korhaz es Egyetemi Oktatokorhaz	Miskolc		Hungary	3526
486	CRU Hungary Kft	Miskolc		Hungary	3529
487	Pecsi Tudomanyegyetem Klinikai Kozpont	Pecs		Hungary	7624
488	Soproni Erzsebet Oktato Korhaz es Rehabilitacios Intezet	Sopron		Hungary	9400
489	Szegedi Tudomanyegyetem Szent Gyorgyi Albert Klinikai Kozpont Altalanos Orvostudomanyi Kar	Szeged		Hungary	6725
490	Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont Altalanos Orvostudomanyi Kar	Szeged		Hungary	6725
491	Praxispont Belvarosi Maganegeszsegugyi Kozpont	Szekesfehervar		Hungary	8000
492	Tolna Megyei Balassa Janos Korhaz	Szekszard		Hungary	7100
493	Csongrad Megyei Dr Bugyi Istvan Korhaz	Szentes		Hungary	6600
494	Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz-Rendelointezet	Szolnok		Hungary	5004
495	Belvarosi Egeszseghaz Kft	Zalaegerszeg		Hungary	8900
496	Hjartamidstodin	Kopavogur		Iceland	201
497	Landspitali	Reykjavik		Iceland	101
498	Ospedale Muscatello	Augusta		Italy	96011
499	Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII	Bergamo		Italy	24127
500	Azienda Ospedaliero Universitaria di Bologna Policlinico S Orsola Malpighi	Bologna		Italy	40138
501	Azienda Ospedaliero Universitaria Mater Domini	Catanzaro		Italy	88100
502	Universita degli Studi Gabriele D Annunzio di Chieti e Pescara	Chieti		Italy	66100
503	Fondazione Toscana Gabriele Monasterio Ospedale del Cuore G Pasquinucci	Massa		Italy	54100
504	IRCCS Ospedale San Raffaele	Milano		Italy	20132
505	Centro Cardiologico Monzino	Milano		Italy	20138
506	Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda	Milano		Italy	20162
507	Azienda Ospedaliero Universitaria Pisana	Pisa		Italy	56100
508	Presidio Ospedaliero Santa Maria delle Grazie	Pozzuoli		Italy	80078
509	Policlinico Universitario Campus Biomedico	Roma		Italy	00128
510	Azienda Ospedaliera Sant Andrea	Roma		Italy	00189
511	IRCCS Policlinico San Donato	San Donato Milanese		Italy	20097
512	Azienda Ospedaliera Citta della Salute e della Scienza di Torino	Torino		Italy	10126
513	Azienda Ospedaliero Universitaria Integrata di Udine	Udine		Italy	33100
514	Inje University Busan Paik Hospital	Busan		Korea, Republic of	47392
515	Dong-A University Hospital	Busan		Korea, Republic of	49201
516	Chungbuk National University Hospital	Cheongju-si, Chungcheongbuk-do		Korea, Republic of	28644
517	Yeungnam University Medical Center	Daegu		Korea, Republic of	42415
518	Keimyung University, Dongsan Hospital	Daegu		Korea, Republic of	42601
519	Chonnam National University Hospital	Gwangju		Korea, Republic of	501-757
520	Gachon University Gil Medical Center	Incheon		Korea, Republic of	21565
521	Seoul National University Bundang Hospital	Seongnam-si, Gyeonggi-do		Korea, Republic of	13620
522	Kyung Hee University Hospital	Seoul		Korea, Republic of	02447
523	Korea University Anam Hospital	Seoul		Korea, Republic of	02841
524	Seoul National University Hospital	Seoul		Korea, Republic of	03080
525	Kangbuk Samsung Hospital	Seoul		Korea, Republic of	03181
526	Severance Hospital, Yonsei University Health System	Seoul		Korea, Republic of	03722
527	Asan Medical Center	Seoul		Korea, Republic of	05505
528	Samsung Medical Center	Seoul		Korea, Republic of	06351
529	The Catholic University of Korea Seoul St Marys Hospital	Seoul		Korea, Republic of	06591
530	Gangnam Severance Hospital	Seoul		Korea, Republic of	135-700
531	Ajou University Hospital	Suwon-si, Gyeonggi-do		Korea, Republic of	16499
532	Yonsei University Wonju Severance Christian Hospital	Wonju-si, Gangwon-do		Korea, Republic of	26426
533	Daugavpils Regional Hospital	Daugavpils		Latvia	5417
534	Dace Teterovska Doctor Practice in Endocrinology	Ogre		Latvia	5001
535	Inga Jasinkevica Cardiologist Practice	Ogre		Latvia	5001
536	Pauls Stradins Clinical University Hospital	Riga		Latvia	1002
537	Outpatient Clinic Veselibas Centrs 4	Riga		Latvia	1012
538	Klinikiniai sprendimai, UAB	Alytus		Lithuania	63200
539	Klinikiniai sprendimai, UAB	Kaunas		Lithuania	49387
540	Saules Seimos Medicinos Centras	Kaunas		Lithuania	49456
541	Hospital of Lithuanian University of Health Sciences Kaunas Clinics Public Institution	Kaunas		Lithuania	50009
542	Kardiologijos ir reabilitacijos klinika, UAB	Klaipeda		Lithuania	91131
543	Siauliai Republican Hospital, Public Institution	Siauliai		Lithuania	76231
544	Vilnius University Hospital Santaros Clinic Public Institution	Vilnius		Lithuania	08661
545	Clinstile SA de CV	Cd De Mexico	Distrito Federal	Mexico	06700
546	Unidad Biomedica Avanzada Monterrey	Monterrey	Nuevo León	Mexico	64460
547	Centro de Estudios Clinicos de Queretaro	Queretaro	Querétaro	Mexico	76000
548	Centro para el Desarrollo de la Medicina y de Asistencia Medica Especializada SC	Culiacan	Sinaloa	Mexico	80230
549	Centro de investigacion Cardiometabolica	Aguascalientes		Mexico	20230
550	Scientia Investigacion Clinica Sc	Chihuahua		Mexico	31203
551	Noordwest Ziekenhuisgroep	Alkmaar		Netherlands	1815 JD
552	Ziekenhuisgroep Twente	Almelo		Netherlands	7609 PP
553	Emotional Brain	Almere		Netherlands	1311 RL
554	Meander Medisch Centrum	Amersfoort		Netherlands	3813 TZ
555	Onze Lieve Vrouwe Gasthuis	Amsterdam		Netherlands	1061 AE
556	Onze Lieve Vrouwe Gasthuis	Amsterdam		Netherlands	1091 AC
557	Academisch Medisch Centrum	Amsterdam		Netherlands	1105 AZ
558	Gelre Ziekenhuis	Apeldoorn		Netherlands	7334 DZ
559	Rijnstate Ziekenhuis	Arnhem		Netherlands	6815 AD
560	Rode Kruis Ziekenhuis	Beverwijk		Netherlands	1942 LE
561	Amphia ziekenhuis	Breda		Netherlands	4818 CK
562	Reinier de Graaf Gasthuis	Delft		Netherlands	2625 AD
563	Huisartsenpraktijk Rambharose	Den Haag		Netherlands	2572 GM
564	Deventer Ziekenhuis	Deventer		Netherlands	7416 SE
565	Van Weel Bethesda Ziekenhuis	Dirksland		Netherlands	3247 BW
566	Albert Schweitzer Ziekenhuis location Dordwijk	Dordrecht		Netherlands	3318 AT
567	Albert Schweitzer Ziekenhuis, Locatie Dordwijk	Dordrecht		Netherlands	3318 AT
568	Ziekenhuis Gelderse Vallei	Ede		Netherlands	6716 RP
569	Catharina Ziekenhuis	Eindhoven		Netherlands	5623 EJ
570	Treant Zorggroep, locatie Scheper ziekenhuis Emmen	Emmen		Netherlands	7824 AA
571	Medisch Spectrum Twente	Enschede		Netherlands	7512 KZ
572	Admiraal de Ruyter Ziekenhuis	Goes		Netherlands	4462 RA
573	Groene Hart Ziekenhuis	Gouda		Netherlands	2803 HH
574	Martini Ziekenhuis	Groningen		Netherlands	9728 NT
575	Sint Jansdal Ziekenhuis	Harderwijk		Netherlands	3844 DG
576	Zuyderland Medisch Centrum	Heerlen		Netherlands	6419 PC
577	Elkerliek Ziekenhuis	Helmond		Netherlands	5707 HA
578	Tergooi	Hilversum		Netherlands	1213 XZ
579	Bethesda Diabetes Research Center	Hoogeveen		Netherlands	7909 AA
580	Dijklander Ziekenhuis Hoorn	Hoorn		Netherlands	1624 NP
581	Medisch Centrum Leeuwarden	Leeuwarden		Netherlands	8934 AD
582	Leids Universitair Medisch Centrum	Leiden		Netherlands	2333 ZA
583	Isala Diaconessenhuis	Meppel		Netherlands	7943 KA
584	Sint Antonius Ziekenhuis, locatie Nieuwegein	Nieuwegein		Netherlands	3435 CM
585	Radboudumc	Nijmegen		Netherlands	6525 GA
586	Canisius-Wilhelmina Ziekenhuis	Nijmegen		Netherlands	6532 SZ
587	Franciscus Gasthuis	Rotterdam		Netherlands	3045 PM
588	Praktijk Soerland	Rotterdam		Netherlands	3067 GJ
589	Maasstad Ziekenhuis	Rotterdam		Netherlands	3079 DZ
590	Ikazia Ziekenhuis	Rotterdam		Netherlands	3083 AN
591	Franciscus Vlietland	Schiedam		Netherlands	3118 JH
592	D&A Research and Genetics	Sneek		Netherlands	8601 ZR
593	Haga Ziekenhuis	The Hague		Netherlands	2545 AA
594	Ziekenhuis Rivierenland	Tiel		Netherlands	4002 WP
595	Elisabeth-Tweesteden Ziekenhuis	Tilburg		Netherlands	5042 AD
596	Ziekenhuis Bernhoven	Uden		Netherlands	5406 PT
597	Diakonessenhuis	Utrecht		Netherlands	3582 KE
598	Universitair Medisch Centrum Utrecht	Utrecht		Netherlands	3584 CX
599	VieCuri Medisch Centrum	Venlo		Netherlands	5912 BL
600	Zaans Medisch Centrum	Zaandam		Netherlands	1502 DV
601	Albert Schweitzer Ziekenhuis	Zwijndrecht		Netherlands	3331 LZ
602	Dokters van Nederhoven	Zwijndrecht		Netherlands	3334 SB
603	Isala Klinieken	Zwolle		Netherlands	8025 AB
604	Szpital Uniwersytecki nr 1 im dr Antoniego Jurasza w Bydgoszczy	Bydgoszcz		Poland	85-094
605	American Heart of Poland Sa Malopolskie Centrum Sercowo-Naczyniowe PAKS - Chrzanow	Chrzanow		Poland	32-500
606	Uniwersyteckie Centrum Kliniczne	Gdansk		Poland	80-219
607	Copernicus Podmiot Leczniczy Sp zoo	Gdansk		Poland	80-462
608	NZOZ Srodmiescie Spzoo	Gdynia		Poland	81-394
609	Marek Piepiorka Gabinet Kardiologiczno-Internistyczny	Gdynia		Poland	81-472
610	Spolka Cywilna Medicina	Gizycko		Poland	11-500
611	Samodzielny Publiczny Specjalistyczny Szpital Zachodni im swietego Jana Pawla II	Grodzisk Mazowiecki		Poland	05-825
612	Biokinetica SA	Jozefow		Poland	05-410
613	Centrum Medyczne Pratia Katowice	Katowice		Poland	40-081
614	Specjalistyczna Poradnia Kardiologiczna i Nadcisnienia Tetniczego Beata Wozakowska-Kaplon	Kielce		Poland	25-525
615	Wojewodzki Szpital Zespolony w Kielcach	Kielce		Poland	25-736
616	Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska	Krakow		Poland	30-082
617	Zespol Przychodni Specjalistycznych Diab-End-Cor Sp z oo	Krakow		Poland	31-135
618	Krakowskie Centrum Medyczne Spzoo	Krakow		Poland	31-501
619	CARINTART Sp zoo Krakowskie Centrum Diagnostyczno-Kliniczne	Krakow		Poland	31-514
620	Intercard Spzoo Centrum Kardiologii Inwazyjnej Elektroterapii i Angiologii w Krosnie	Krosno		Poland	38-400
621	Samodzielny Publiczny Zakład Opieki Zdrowotnej w Lecznej	Leczna		Poland	21-010
622	Wojewodzki Specjalistyczny Szpital im dr Wladyslawa Bieganskiego w Lodzi	Lodz		Poland	91-347
623	Instytut Centrum Zdrowia Matki Polki	Lodz		Poland	93-338
624	Miedziowe Centrum Zdrowia Spolka Akcyjna	Lubin		Poland	59-300
625	CenterMed Lublin Spzoo	Lublin		Poland	20-044
626	Clinical Best Solutions Sp zoo Spolka komandytowa Gabinet Lekarski	Lublin		Poland	20-078
627	Ko-med Centra Kliniczne Lublin II	Lublin		Poland	20-362
628	NZOZ Twoja Przychodnia Spzoo	Lublin		Poland	20-857
629	Szpital Swietej Anny w Miechowie	Miechow		Poland	32-200
630	Podhalanski Szpital Specjalistyczny im Jana Pawla II w Nowym Targu	Nowy Targ		Poland	34-400
631	Centrum Medyczne Pulawska spzoo Centrum Medyczne Pulawska NZOZ	Piaseczno		Poland	05-500
632	NZOZ Specjalistyczna Przychodnia Lekarska Medikard	Plock		Poland	09-402
633	Clinical Research Center Spzoo Medic-R Spolka Komandytowa	Poznan		Poland	60-848
634	KO-MED Centra Kliniczne Spzoo KO-MED Centra Kliniczne Pulawy	Pulawy		Poland	24-100
635	NZOZ Przychodnia Specjalistyczna Andrzej Wittek Henryk Rudzki spolka jawna	Ruda Slaska		Poland	41-709
636	Clinical Best Solutions Spolka z ograniczona odpowiedzialnoscia Spolka komandytowa	Siedlce		Poland	08-110
637	ETG Network Spzoo	Skierniewice		Poland	96-100
638	KO-MED Centra Kliniczne Spzoo KO-MED Centra Kliniczne Staszow	Staszow		Poland	28-200
639	Tomasz Blicharski Lubelskie Centrum Diagnostyczne	Swidnik		Poland	21-040
640	Indywidualna Specjalistyczna Praktyka Lekarska	Szczecin		Poland	70-506
641	Centrum Szybkiej Diagnostyki Kardiologicznej Kardiomed M Zabowka E Zabowka Spolka cywilna	Tarnow		Poland	33-100
642	Medical Trials Institute Spzoo	Torun		Poland	87-100
643	Prywatne Centrum Kardiologii	Torun		Poland	87-100
644	Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu	Torun		Poland	87-100
645	Centrum Medyczne Amed Warszawa Zoliborz	Warszawa		Poland	01-518
646	Centrum Medyczne Pratia Warszawa	Warszawa		Poland	01-868
647	Clinical Best Solutions Sp zoo Spolka komandytowa	Warszawa		Poland	02-793
648	Instytut Psychiatrii i Neurologii	Warszawa		Poland	02-957
649	Szpital Grochowski imienia Doktora medycyny Rafala Masztaka Spzoo	Warszawa		Poland	04-073
650	Samodzielny Publiczny Zaklad Opieki Zdrowotnej w Wegrowie	Wegrow		Poland	07-100
651	Medicor Plus Kardiolodzy Spzoo	Wloclawek		Poland	87-800
652	Futuremeds spolka z ograniczona odpowiedzialnoscia	Wroclaw		Poland	50-088
653	Centrum Kardiologiczne Pro Corde Spzoo Centrum Kardiologicne Pro Corde Wroclaw	Wroclaw		Poland	50-315
654	Centrum Badan Klinicznych Piotr Napora Lekarze Spolka Partnerska	Wroclaw		Poland	51-162
655	KO-MED Centra Kliniczne Spzoo KO-MED Centra Kliniczne Zamosc	Zamosc		Poland	22-400
656	Hospital Garcia de Orta, EPE	Almada		Portugal	2801-951
657	Centro Hospitalar do Baixo Vouga, EPE - Hospital Infante Dom Pedro	Aveiro		Portugal	3814-501
658	Centro Hospitalar de Lisboa Ocidental, EPE - Hospital de Santa Cruz	Carnaxide		Portugal	2790-134
659	Centro Hospitalar e Universitario de Coimbra EPE	Coimbra		Portugal	3000-075
660	Hospital de Faro, EPE	Faro		Portugal	8000-386
661	Hospital da Senhora da Oliveira, Guimaraes, EPE	Guimaraes		Portugal	4835-044
662	Associacao Protectora dos Diabeticos de Portugal	Lisboa		Portugal	1250-189
663	Unidade Local de Saude de Matosinhos - Hospital Pedro Hispano	Matosinhos		Portugal	4464-513
664	Hospital Casa de Saude Sao Mateus	Viseu		Portugal	3500-093
665	SC Centrul Medical de Diagnostic si Tratament Ambulator Neomed S.R.L	Brasov		Romania	500283
666	Spitalul Universitar de Urgenta Bucuresti	Bucharest		Romania	050098
667	Spitalul Clinic Universitar de Urgenta Elias	Bucuresti		Romania	011461
668	Institutul de Urgenţă pentru Boli Cardiovasculare "Prof. Dr. C. C. Iliescu",	Bucuresti		Romania	022328
669	Cardiomed SRL	Craiova		Romania	200512
670	Consultmed SRL	Iasi		Romania	700547
671	SC Cardiomed SRL	Iasi		Romania	700732
672	SC Endodigest SRL	Oradea		Romania	410151
673	SC Sal Med SRL	Pitesti		Romania	110438
674	Mediab SRL	Targu Mures		Romania	540142
675	CMI Dr Podoleanu Cristian	Targu Mures		Romania	540143
676	First City Clinical Hospital na E E Volosevich	Arkhangelsk		Russian Federation	163001
677	NSHI Departmental Hospital at the station Barnaul of OJSC Russian Railways	Barnaul		Russian Federation	656038
678	Regional State Budget Health care Institution Altay Regional Cardiology Dispensary	Barnaul		Russian Federation	656055
679	Central City Clinical Hospital 1 of the Oktyabrsky District	Ekaterinburg		Russian Federation	620026
680	State Budget Medical Institution Sverdlovsk Regional Clinical Hospital N1	Ekaterinburg		Russian Federation	620102
681	Regional Budget Healthcare Institution Cardiology Dispensary	Ivanovo		Russian Federation	153012
682	BHI of Republic Udmurtiya City clinical hospital 9 of Ministry of healthcare of Republic Udmurtiya	Izhevsk		Russian Federation	426063
683	FSBI Heart and Vessels Diseases complex problems Scientific Research Institution	Kemerovo		Russian Federation	650002
684	Kirov Regional State Budget Healthcare Institution Kirov City Clinical Hospital 1	Kirov		Russian Federation	610014
685	Regional Clinical Hospital 2 of the Ministry of Health Krasnodar region	Krasnodar		Russian Federation	350012
686	SBHI Scientific Research Institute Regional Clinical Hospital 1 named after S V Ochapovsky	Krasnodar		Russian Federation	350086
687	National Medical Research Center for therapy and preventive medicine	Moscow		Russian Federation	101990
688	Moscow SBHI City Clinical Hospital 15 n a O M Filatov of Moscow Healthcare Department	Moscow		Russian Federation	111539
689	SBHI of Moscow City clinical hospital 64 of Moscow Healthcare department	Moscow		Russian Federation	117292
690	City Clinical Hospital named after Zhadkevich	Moscow		Russian Federation	121374
691	FSBI Russian Cardiology Research and Production Complex	Moscow		Russian Federation	121552
692	SBHI of Nizhny Novgorod region Nizhny Novgorod regional clinical hospital na N A Semashko	Nizhny Novgorod		Russian Federation	603126
693	LLC RC Medical	Novosibirsk		Russian Federation	630005
694	SBHI of Novosibirsk Region City clinical hospital 1	Novosibirsk		Russian Federation	630047
695	FSBSI Scientific Research Institute of Therapy and preventive medicine	Novosibirsk		Russian Federation	630089
696	Budget Healthcare Institution of Omsk region Medical-sanitary unit 9	Omsk		Russian Federation	644018
697	Perm Regional Hospital for War Veterans	Perm		Russian Federation	614097
698	State Budget Institution of Ryazan Region Regional Clinical Hospital	Ryazan		Russian Federation	390039
699	SBHI Medical and sports dispensary of Krasnogvardeisky district of Saint Petersburg	Saint Petersburg		Russian Federation	195112
700	Almazov National Medical Research Centre	Saint Petersburg		Russian Federation	197341
701	Saint Petersburg State Budget Healthcare Institution City Polyclinic 109	Saint-Petersburg		Russian Federation	192283
702	Saint Petersburg State Budget Healthcare Institution City Polyclinic 109	Saint-Petersburg		Russian Federation	192289
703	City polyclinic 25 Nevsky district	Saint-Petersburg		Russian Federation	193312
704	Saint Petersburg SBHI City Hospital 38 named after N A Semashko	Saint-Petersburg		Russian Federation	196601
705	Saint Petersburg State Budget Healthcare Institution Pokrovskaya City Hospital	Saint-Petersburg		Russian Federation	199106
706	LLC Mart	Saint-Petersburg		Russian Federation	199178
707	LLC Medinef Clinic	Sait-Petersburg		Russian Federation	194044
708	Samara Regional Clinical Cardiology Dispensary	Samara		Russian Federation	443070
709	Clinical Hospital named after S R Mirotvortsev	Saratov		Russian Federation	410054
710	Regional State Budget Helthcare Institution Smolensk Regional Clinical Hospital	Smolensk		Russian Federation	214018
711	State Budgetary Health Institution City Hospital 4 of the City of Sochi	Sochi		Russian Federation	354057
712	City Polyclinic 27	St. Petersburg		Russian Federation	190031
713	FSBSI Tomsk National Research Medical Center of the Russian Academy of Sciences	Tomsk		Russian Federation	634012
714	Tyumen State Medical University	Tyumen		Russian Federation	625023
715	State Autonomous Healthcare Institution of the Tyumen region Medical Scientific Practical Center	Tyumen		Russian Federation	625032
716	SBHI of Vladimirskaya region City Hospital 4 of Vladimir	Vladimir		Russian Federation	600020
717	Family Medicine Clinic	Volgograd		Russian Federation	400001
718	Alian, sro	Bardejov		Slovakia	085 01
719	MediTask, sro	Bratislava		Slovakia	831 03
720	Narodny ustav srdcovych a cievnych chorob, as	Bratislava		Slovakia	833 48
721	Veria, sro	Bratislava		Slovakia	851 01
722	Nemocnica s poliklinikou Brezno, no	Brezno		Slovakia	977 01
723	Medical group Kosice sro	Kosice		Slovakia	040 01
724	Cardio D and R, sro Kosice	Kosice		Slovakia	040 22
725	Kardio 1 sro	Lucenec		Slovakia	984 01
726	Medi M and M sro	Moldava nad Bodvou		Slovakia	045 01
727	Oralek, sro	Namestovo		Slovakia	029 01
728	Kardiocentrum Nitra sro	Nitra		Slovakia	949 01
729	Kardiomed NZ, sro	Nove Zamky		Slovakia	940 01
730	Medikard, sro	Presov		Slovakia	080 01
731	Medispol, sro	Presov		Slovakia	080 01
732	Diab sro	Roznava		Slovakia	048 01
733	Mediluk sro	Snina		Slovakia	069 01
734	Interna SK, sro	Svidnik		Slovakia	089 01
735	Areteus sro	Trebisov		Slovakia	075 01
736	CardiOr, sro	Trencin		Slovakia	911 01
737	Hospital Virgen del Mar	Almeria	Andalucía	Spain	04120
738	Hospital Universitario Reina Sofia	Cordoba	Andalucía	Spain	14004
739	Hospital Universitario Virgen de las Nieves	Granada	Andalucía	Spain	18012
740	Hospital Clinico Universitario Virgen de la Victoria	Malaga	Andalucía	Spain	29010
741	Hospital Universitario Virgen Macarena	Sevilla	Andalucía	Spain	41009
742	Hospital Universitario Miguel Servet	Zaragoza	Aragón	Spain	50009
743	Hospital Universitario de Gran Canaria Doctor Negrin	Las Palmas De Gran Canarias	Canarias	Spain	35010
744	Hospital Clinico Universitario de Valladolid	Valladolid	Castilla León	Spain	47005
745	Hospital Universitari Germans Trias i Pujol	Badalona	Cataluña	Spain	08916
746	Equip Atencio Primaria Sardenya	Barcelona	Cataluña	Spain	08025
747	Hospital Clinic i Provincial de Barcelona	Barcelona	Cataluña	Spain	08036
748	Hospital Universitari Sant Joan de Reus	Reus	Cataluña	Spain	43204
749	Hospital Universitari i Politecnic La Fe	Valencia	Comunidad Valenciana	Spain	26026
750	Hospital Clinico Universitario de Valencia	Valencia	Comunidad Valenciana	Spain	46010
751	Complexo Hospitalario Universitario A Coruña	A Coruña	Galicia	Spain	15006
752	Hospital Clinico Universitario de Santiago	Santiago de Compostela	Galicia	Spain	15706
753	Hospital Alvaro Cunqueiro	Vigo	Galicia	Spain	36312
754	Hospital Universitario Virgen de la Arrixaca	El Palmar	Murcia	Spain	30120
755	Complejo Hospitalario de Navarra	Pamplona	Navarra	Spain	31008
756	Hospital Universitario de La Princesa	Madrid		Spain	28006
757	Fundacion Jimenez Diaz	Madrid		Spain	28040
758	Hospital Clinico San Carlos	Madrid		Spain	28040
759	Hospital Universitario 12 de Octubre	Madrid		Spain	28041
760	Hospital Universitario La Paz	Madrid		Spain	28046
761	Hospital Universitario Infanta Sofia	Madrid		Spain	28702
762	Sodra Alvsborgs sjukhus	Boras		Sweden	501 82
763	Falu Lasarett	Falun		Sweden	791 82
764	Carlanderska	Goteborg		Sweden	405 45
765	Sahlgrenska Universitetssjukhus	Goteborg		Sweden	413 45
766	Obackakliniken i Harnosand	Harnosand		Sweden	871 31
767	PharmaSite Helsingborg	Helsingborg		Sweden	252 20
768	Lanssjukhuset Ryhov	Jonkoping		Sweden	551 85
769	Centralsjukhuset Karlstad	Karlstad		Sweden	651 85
770	Skaraborgs sjukhus Lidkoping	Lidkoping		Sweden	531 85
771	Clemenstorgets Hjartmottagning	Lund		Sweden	222 21
772	PharmaSite Malmo	Malmo		Sweden	211 52
773	Ostersunds sjukhus	Ostersund		Sweden	831 83
774	Akardo MedSite	Stockholm		Sweden	117 27
775	Norrlands Universitetssjukhus	Umea		Sweden	901 85
776	Hallands sjukhus Varberg	Varberg		Sweden	432 81
777	Hualien Tzu Chi Hospital	Hualien		Taiwan	97002
778	Kaohsiung Medical University Chung-Ho Memorial Hospital	Kaohsiung		Taiwan	80756
779	Kaohsiung Chang Gung Memorial Hospital	Kaohsiung		Taiwan	83301
780	Mackay Memorial Hospital Tamsui Branch	New Taipei		Taiwan	25160
781	Chung Shan Medical University Hospital	Taichung		Taiwan	40201
782	Taichung Veterans General Hospital	Taichung		Taiwan	40705
783	National Cheng Kung University Hospital	Tainan		Taiwan	70403
784	National Taiwan University Hospital	Taipei		Taiwan	10002
785	Taipei Veterans General Hospital	Taipei		Taiwan	11217
786	Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation	Taoyuan		Taiwan	33305
787	Ivano-Frankivsk Regional Clinical Cardiology Center of Ivano-Frankivsk Regional Council	Ivano-Frankivsk		Ukraine	76018
788	Communal Healthcare Institution Kharkiv City Clinical Hospital No27	Kharkiv		Ukraine	61002
789	Medical and Sanitary Unit of Open Joint Stock Company Kharkiv Tractor Plant	Kharkiv		Ukraine	61106
790	Communal Noncommercial enterprise "City Hospital #8" of Kharkiv City Council	Kharkiv		Ukraine	61176
791	Oleksandrivska Clinical Hospital of Kyiv	Kyiv		Ukraine	01023
792	Kyiv City Clinical Hospital 1	Kyiv		Ukraine	02091
793	Communal Noncommercial Institution Consultative and Diagnostic Center of Desnianskyi District of Kyi	Kyiv		Ukraine	02232
794	Kyiv City Clinical Emergency Medical Care Hospital	Kyiv		Ukraine	02660
795	National Scientific Center "M.D. Strazhesko Institute of Cardiology"	Kyiv		Ukraine	03151
796	State Institution National Scientific Center Acad MD Strazhesko Institute of cardiology of NAMS Ukr	Kyiv		Ukraine	03680
797	State Institution National Scientific Center Acad Strazhesko Institute of Cardiology	Kyiv		Ukraine	03680
798	Medical Centre CONSILIUM Medical	Kyiv		Ukraine	04050
799	Zakarpattia Oblast Clinical Center of Cardiology and Cardio Surgery	Uzhgorod		Ukraine	88014
800	Vinnytsia M I Pyrogov Regional Clinical Hospital Vinnytsia M I Pyrogov National Medical University	Vinnytsia		Ukraine	21018
801	Private Small Enterprise, Medical Center Pulse	Vinnytsya		Ukraine	21001
802	Communal Non-commercial enterprise "City Hospital #6 "of Zaporizhzhia City Council	Zaporizhzhia		Ukraine	69035
803	Aberdeen Royal Infirmary	Aberdeen		United Kingdom	AB25 2ZN
804	Barnsley Hospital	Barnsley		United Kingdom	S75 2EP
805	Royal United Hospital	Bath		United Kingdom	BA1 3NG
806	Royal Victoria Hospital	Belfast		United Kingdom	BT12 6BA
807	Ulster Hospital	Belfast		United Kingdom	BT16 1RH
808	Ormeau Health Centre	Belfast		United Kingdom	BT7 2EB
809	Bollington Medical Centre	Bollington		United Kingdom	SK10 5JH
810	Royal Bournemouth Hospital	Bournemouth		United Kingdom	BH7 7DW
811	West Walk Surgery	Bristol		United Kingdom	BS37 4AX
812	University Hospitals of Derby and Burton NHS Foundation Trust	Burton upon Trent		United Kingdom	DE13 0RB
813	Ashgate Medical Practice	Chesterfield		United Kingdom	S40 4AA
814	Cleveleys Group Practice	Cleveleys		United Kingdom	FY5 3LF
815	Lakeside Healthcare	Corby		United Kingdom	NN17 2UR
816	Medinova Northamptonshire Dedicated Research Site	Corby		United Kingdom	NN18 9EZ
817	MeDiNova Warwickshire Quality Research Site	Coventry		United Kingdom	CV3 4FJ
818	Pound Hill Medical Group	Crawley		United Kingdom	RH10 7DX
819	Ninewells Hospital	Dundee		United Kingdom	DD1 9SY
820	Glasgow Royal Infirmary	Glasgow		United Kingdom	G31 2ER
821	Hull Royal Infirmary	Hull		United Kingdom	HU3 2RW
822	Highlands Clinical Research Facility, Raigmore Hospital	Inverness		United Kingdom	IV2 3JH
823	Sherbourne Medical Centre	Leamington Spa		United Kingdom	CV32 4RA
824	Royal Liverpool University Hospital	Liverpool		United Kingdom	L7 8XP
825	Barts Health NHS Trust	London		United Kingdom	EC1M 6BQ
826	Royal Free London NHS Foundation Trust	London		United Kingdom	NW3 2QG
827	Guys Hospital	London		United Kingdom	SE1 9RT
828	Wythenshawe Hospital	Manchester		United Kingdom	M23 9LT
829	Medinova North London Dedicated Research Centre	Northwood		United Kingdom	HA6 2RN
830	Nottingham City Hospital	Nottingham		United Kingdom	NG5 1PB
831	George Eliot Hospital	Nuneaton		United Kingdom	CV10 7DJ
832	Medinova South London Dedicated Research Centre	Orpington		United Kingdom	BR5 3QG
833	Mounts Bay Medical Hub	Penzance		United Kingdom	TR19 7HX
834	The Health Centre Yaxley	Peterborough		United Kingdom	PE7 1AT
835	The Adam Practice	Poole		United Kingdom	BH16 5PW
836	Medinova East London Dedicated Research Centre	Romford		United Kingdom	RM1 3PJ
837	Ashfield Primary Care Centre	Sandbach		United Kingdom	CW11 1EQ
838	Scunthorpe General Hospital	Scunthorpe		United Kingdom	DN15 7BH
839	Medinova Limited	Shipley		United Kingdom	BD18 3SA
840	Eaton Socon Health Centre	St Neots		United Kingdom	PE19 8BB
841	Lakeside Healthcare Stamford	Stamford		United Kingdom	PE9 2DH
842	Lister Hospital	Stevenage		United Kingdom	SG1 4AB
843	Singleton Hospital	Swansea		United Kingdom	SA2 8PP
844	The Breckland Alliance	Thetford		United Kingdom	IP24 1JD
845	Torbay Hospital	Torquay		United Kingdom	TQ2 7AA
846	Pinderfields Hospital	Wakefield		United Kingdom	WF1 4DG
847	Sheepcot Medical Practice	Watford		United Kingdom	WD25 7NL
848	Sandwell General Hospital	West Bromwich		United Kingdom	B71 4HJ
849	Whitby Group Practice	Whitby		United Kingdom	YO21 1SD
850	MeDiNova West London Quality Research Site	Wokingham		United Kingdom	RG40 1XS
851	Worcestershire Royal Hospital	Worcester		United Kingdom	WR5 1DD
852	Yeovil District Hospital	Yeovil		United Kingdom	BA21 4AT