The Correlation Between the Barium Examination and High Resolution Impedance Manometry

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT04878588
Collaborator
(none)
20
68.1

Study Details

Study Description

Brief Summary

In many cases, the manometric examination is not feasible because of the pharyngeal sinusitis or pharyngeal torsion. In addition, although previous conventional manometry was used to estimate pharyngeal swallowing, the bolus flow transmission was still not evaluated, which still depended on the videofluoscopic swallowing studies. High resolution impedance manometry could help us to measure the bolus flow according to the impedance changes. However, the comparison between two approach methods of postoperative recovery of swallowing function is still inconclusive. In this study, we aimed to examine the correlation between high-resolution manometric and videofluoroscopic (Barium) measurements of the swallowing function.

Condition or Disease Intervention/Treatment Phase
  • Other: patients received high resolution impedance manometry

Detailed Description

In many cases, the manometric examination is not feasible because of the pharyngeal sinusitis or pharyngeal torsion. In addition, although previous conventional manometry was used to estimate pharyngeal swallowing, the bolus flow transmission was still not evaluated, which still depended on the videofluoscopic swallowing studies. High resolution impedance manometry (HRIM) could help us to measure the bolus flow according to the impedance changes. However, the comparison between two approach methods of postoperative recovery of swallowing function is still inconclusive.

In this study, we aimed to examine the correlation between high-resolution manometric and videofluoroscopic (Barium) measurements of the swallowing function.

For the patients and method decription, consecutive patients who will fulfill the criteria of elective esophagectomy patients aged >= 20 will be enrolled. After got the inform consent, these patients receive the swallowing function by barium examination and HRIM.

Study Design

Study Type:
Observational
Anticipated Enrollment :
20 participants
Observational Model:
Case-Only
Time Perspective:
Cross-Sectional
Official Title:
The Correlation Between High Resolution Impedance Manometry and Videofluoroscopic Measurements of Swallowing Function After Patients Undergoing Esophagectomy
Anticipated Study Start Date :
Sep 6, 2021
Anticipated Primary Completion Date :
May 10, 2025
Anticipated Study Completion Date :
May 10, 2027

Arms and Interventions

Arm Intervention/Treatment
patients receiving esophagectomy

the patients receiving esophagectomy during perioperative period. They receive barium examination and high resolution impedance manometry at the same time

Other: patients received high resolution impedance manometry
patients received the above two examination at the same time
Other Names:
  • patients received barium examination
  • Outcome Measures

    Primary Outcome Measures

    1. the contractility of the muscle at the upper gastrointestinal tract [20 minutes]

      the contractility at the upper gastrointestinal tract muscle

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    20 Years to 80 Years
    Sexes Eligible for Study:
    All
    Inclusion Criteria:
    • patients receiving elective esopagectomy
    Exclusion Criteria:
    • patients with major organ disease, such as heart, lung, or liver disease

    • patients with coagulopathy

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • National Taiwan University Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    National Taiwan University Hospital
    ClinicalTrials.gov Identifier:
    NCT04878588
    Other Study ID Numbers:
    • 202102001RIND
    First Posted:
    May 7, 2021
    Last Update Posted:
    Sep 14, 2021
    Last Verified:
    Sep 1, 2021
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No

    Study Results

    No Results Posted as of Sep 14, 2021