Correlation Analysis Between Corneal Biomechanics and Anterior Segment

• Sponsor: Tianjin Eye Hospital (Other)
• Overall Status: Completed
• CT.gov ID: NCT06109636
• Collaborator: (none)
• Enrollment: 50
• Location: 1
• Actual Duration (Months): 6.9
• Patients Per Site Per Month: 7.2

Study Details

Study Description

Brief Summary

Evaluation of the ciliary muscle thickness, area, and anterior chamber angle, as well as anterior sclera thickness in subjects, to investigate the relationship between these measurements and corneal biomechanics. Clarify whether aqueous humor displacement, anterior sclera, and ciliary muscles influence the assessment of in vivo corneal biomechanics.

Condition or Disease	Intervention/Treatment	Phase
Ciliary Muscle Thickness; Anterior Sclera Thickness; Corneal Biomechanics; CASIA2	Other: Pentacam, Corvis ST and Casia2

Study Design

• Study Type: Observational
• Actual Enrollment: 50 participants
• Observational Model: Case-Only
• Time Perspective: Prospective
• Official Title: Correlation Analysis Between In-vivo Corneal Biomechanical Properties and Anterior Segment in Chinese Population
• Actual Study Start Date: Mar 4, 2023
• Actual Primary Completion Date: Oct 1, 2023
• Actual Study Completion Date: Oct 1, 2023

Arms and Interventions

Arm	Intervention/Treatment
Normal group	Other: Pentacam, Corvis ST and Casia2; scleral and ciliary muscle thickness were obtained by Casia2, biomechanical parameters were obtained by Pentacam and Corvis ST

Outcome Measures

Primary Outcome Measures

1. scleral and ciliary muscle thickness [one year]

   The thickness of scleral and ciliary muscle(Casia2, quantitative data through the utilization of its integrated ruler system)

2. biomechanical parameters [one year]

   The biomechanical parameters(Corvis ST, exporting the quality-assured csv files to analysis)

Eligibility Criteria

Criteria

• Ages Eligible for Study: N/A and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

1. Best corrected visual acuity (BCVA) ≥ 20/20;

2. No other eye diseases except myopia and astigmatism;

3. The cornea was transparent, and there was no cloud or pannus;

Exclusion Criteria:

1. Corneal disease;

2. Ocular trauma;

3. Previous ocular surgery;

4. Any anterior segment diseases except cataract;

5. Patients were required to stop wearing soft contact lenses for at least 2 weeks and rigid contact lenses for at least 4 weeks before examination;

6. Pregnant and lactating women;

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Tiajin Eye Hospital	Tianjin	Tianjin	China

Sponsors and Collaborators

• Tianjin Eye Hospital

Investigators

• Study Chair: Yan Wang, Prof, Tianjin Eye Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Tianjin Eye Hospital
• ClinicalTrials.gov Identifier: NCT06109636
• Other Study ID Numbers: KY2023025
• First Posted: Oct 31, 2023
• Last Update Posted: Oct 31, 2023
• Last Verified: Oct 1, 2023

• Individual Participant Data (IPD) Sharing Statement: Undecided
• Plan to Share IPD: Undecided
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Study Results

No Results Posted as of Oct 31, 2023