Correlation Between OCT and mFERG Findings With VA After Vitrectomy Surgery for Retinal Detachment

Sponsor
New Valley University (Other)
Overall Status
Completed
CT.gov ID
NCT05993208
Collaborator
Assiut University (Other)
40
1
5.9
6.7

Study Details

Study Description

Brief Summary

Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity after vitrectomy surgery for Retinal detachment.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: optical coherence tomography,multifocal electroretinogram. VA measurment

Detailed Description

Although the anatomical success rate of vitreoretinal surgery has improved over the last decade, visual results remain compromised? Patients with macula-off retinal detachments (RDs) can have poor visual recovery, specific color vision defects, or metamorphopsia postoperatively despite successful retinal reattachment. In these cases, subtle changes in the foveal structure may be causing visual disturbances that can be difficult to identify during standard clinical examinations such as slit lamp biomicroscopy or binocular indirect ophthalmoscopy .reported a possible association between incomplete visual recovery and the presence of residual subretinal fluid (SRF) postoperatively.

Optical coherence tomography (OCT) is a non-invasive technique that provides information about the morphology of the retina, and especially of the macular area in vivo. Some studies support the idea that OCT determines structural changes in the macula that are correlated with subjective visual function, including visual acuity (VA) in patients with vitrectomy for retinal detachment. Additionally, multifocal electroretinogram (m fERG) evaluation can be helpful in assessing macular function in post-vitrectomy. However, to date, there are relatively few reports concerning the combined use of OCT and m fERG for the correlation between retinal morphology and function of the macula in patients with vitrectomy for retinal detachment surgery. The purpose of our study is to determine whether a significant correlation exists between the amplitude of m fERG, visual acuity, and the morphological OCT changes by in the macula after vitrectomy for retinal detachment

Study Design

Study Type:
Observational
Actual Enrollment :
40 participants
Observational Model:
Case-Only
Time Perspective:
Retrospective
Official Title:
Correlation Between Optical Coherence Tomography and Multifocal Electroretinogram Findings With Visual Acuity After Vitrectomy Surgery for Retinal Detachment
Actual Study Start Date :
Jan 1, 2023
Actual Primary Completion Date :
May 1, 2023
Actual Study Completion Date :
Jul 1, 2023

Outcome Measures

Primary Outcome Measures

  1. CMT,BCVAand mf-ERG were recoreded in 40 eyes of 40 patintes with vitrectomy for retinal detchament surgery . [6 months]

    Each 10 um increase in central (CMT) associated by how increase decimal in Best corrected visual acuity and by how nV/deg2 increase multifocal electroretinogram in these eyes .

  2. BCVA(best corrected visual acuity) [6 Month]

    Best corrected Visual acuity measurement using Snellen's Acuity Chart and will be expressed as decimal notation

  3. CMT(central macualr thikness ) um [6 month]

    centeral macualr thikness mesurment using using optical chorent tomgraphgy

  4. mf-ERG amplituide nV/deg2 [6 month]

    multifocal electroretinogram amplituide mesurement using mf-ERG machine

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • patients with successful vitrectomy for retinal detachment.
Exclusion Criteria:
  • The patients who had vitrectomy for reasons other than retinal detachment surgery

  • Patients who had done scleral buckle surgery

  • Patients with media opacity are prevented from doing retina imaging.

  • Failed or recurrent vitrectomy surgery

Contacts and Locations

Locations

Site City State Country Postal Code
1 New Vally University Sohag Egypt

Sponsors and Collaborators

  • New Valley University
  • Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Asmaa Kamel Ahmed Hassan, lecture, New Valley University
ClinicalTrials.gov Identifier:
NCT05993208
Other Study ID Numbers:
  • CBOCT&MFERG&VA-VRD
First Posted:
Aug 15, 2023
Last Update Posted:
Aug 21, 2023
Last Verified:
Aug 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Aug 21, 2023