The Correlation Between Sevoflurane and qNOX

• Sponsor: China International Neuroscience Institution (Other)
• Overall Status: Completed
• CT.gov ID: NCT03665792
• Collaborator: (none)
• Enrollment: 58
• Location: 1
• Actual Duration (Months): 6.6
• Patients Per Site Per Month: 8.7

Study Details

Study Description

Brief Summary

This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the correlation between the sevoflurane and NOX index.

Condition or Disease	Intervention/Treatment	Phase
Analgesic Adverse Reaction; Nociceptive Pain; Inhalation; Vapor	Device: nociception index qNOX

Detailed Description

This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the analgesia effect of the sevoflurane.

And test the correlation between the sevoflurane and NOX index.

Study Design

• Study Type: Observational
• Actual Enrollment: 58 participants
• Observational Model: Other
• Time Perspective: Cross-Sectional
• Official Title: The Prospective Observational Research of the Analgesic Effect of Sevoflurane and the Correlation Between Sevoflurane and qNOX
• Actual Study Start Date: Feb 11, 2019
• Actual Primary Completion Date: Sep 1, 2019
• Actual Study Completion Date: Sep 1, 2019

Outcome Measures

Primary Outcome Measures

1. The sevoflurane application correlated with the qNOX index [through study completion, an average of 1 year]

   The sevoflurane application correlated with the qNOX index, meanwhile reflect the analgesia effect of sevoflurane application

Eligibility Criteria

Criteria

• Ages Eligible for Study: 25 Years to 85 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

1. Elective thoracoscope surgery patients

2. Age ranging from 25 to 85 years

3. American Society of Anesthesiologists (ASA) Physical Status score of 2 to 4

4. a body mass index (BMI) ranging from 18.5 to 40 kg/m2.

Exclusion Criteria:

1. Clinical diagnosis of Alzheimer's Disease

2. implanted pacemaker

3. Clinical diagnosis of psychiatric diseases

4. Clinical diagnosis of epilepsy

5. Clinical diagnosis of autonomic nervous system disorders which might affect the EEG

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Bei Liu	Beijing	Beijing	China	100053

Sponsors and Collaborators

• China International Neuroscience Institution

Investigators

• Principal Investigator: Xiaohua Wang, MD,PHD, Xuanwu Hospital, Beijing

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: China International Neuroscience Institution
• ClinicalTrials.gov Identifier: NCT03665792
• Other Study ID Numbers: CINI-ZYLX-201806-11
• First Posted: Sep 11, 2018
• Last Update Posted: Jan 22, 2020
• Last Verified: Jan 1, 2020

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Nociceptive Pain

Study Results

No Results Posted as of Jan 22, 2020