Correlation Between the Visual Acuity & the OCT Pattern of Macular Edema Secondary to RVO
Study Details
Study Description
Brief Summary
Correlation between changes observed in OCT and VA in patients with retinal vein occlusion whether the patient's VA improves when macular edema improves in OCT or not ??
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
Central retinal vein occlusion (CRVO) is a common retinal vascular disorder. Clinically, CRVO presents with variable visual loss; fundus may show retinal hemorrhages, dilated tortuous retinal veins, cotton-wool spots, macular edIn view of the devastating complications associated with the severe form of CRVO, number of classifications were described. All of classifications take into account the area of retinal capillary nonperfusion and development of neovascular complications.
CRVO can be divided into 2 clinical types, ischemic and nonischemic. In addition, a number of patients may have an intermediate presentation with variable clinical course. On initial presentation, it may be difficult to classify a given patient, since CRVO may change with time.
A number of clinical and ancillary investigative factors are taken into account for classifying CRVO:
Nonischemic CRVO is milder form of disease. It may present with good vision, few retinal hemorrhages and cotton-wool spots, no relative afferent pupillary defect, and good perfusion to the retina. Nonischemic CRVO may resolve fully with good visual outcome or may progress to the ischemic type.
Ischemic CRVO is the severe form of the disease. CRVO may present initially as the ischemic type, or it may progress from nonischemic. Usually, ischemic CRVO presents with severe visual loss, extensive retinal hemorrhages and cotton-wool spots, presence of relative afferent pupillary defect, poor perfusion to retina, and presence of severe electroretinographic changes. In addition, patients may end up with neovascular glaucoma and a painful blind eye.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Patients with macular edema due to RVO assessment of visual acuity using Landolt chart and follow up of macular edema using OCT |
Device: OCT
Assessment of macular edema secondary to retinal vein occlusion usin optical coherence tomography and its correlation with visual acuity
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Outcome Measures
Primary Outcome Measures
- Macular edema assessment [5 minutes]
Macular edema assessed by OCT in microns
- Visual acuity assessment [5 minutes]
Visual acuity assessment through Landolt chart
Secondary Outcome Measures
- Causes of non improvement of visual acuity in patients with resolving macular edema [5 minutes]
To detect causes of visual non improvement with visual acuity measured through Landolt chart in patients with resolving macular edema measured by OCT device in microns
Eligibility Criteria
Criteria
Inclusion Criteria:
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Patients with macular edema related to vein occlusion .
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Patient's Age above 18 years old .
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Patients able to sit on OCT device .
Exclusion Criteria:
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Significant cataract .
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Media opacities as vitreous haemorrhage .
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patients with macular edema related to CRVO treated by laser photocoagulation .
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patients with glaucoma .
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Patients with chronic uveitis.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Assiut University
Investigators
- Study Chair: Abdelsalam a Mohamed, ass. prof., Assiut University
Study Documents (Full-Text)
None provided.More Information
Publications
- Hayreh SS. Classification of central retinal vein occlusion. Ophthalmology. 1983 May;90(5):458-74.
- Hayreh SS. Retinal vein occlusion. Indian J Ophthalmol. 1994 Sep;42(3):109-32. Review.
- Natural history and clinical management of central retinal vein occlusion. The Central Vein Occlusion Study Group. Arch Ophthalmol. 1997 Apr;115(4):486-91. Erratum in: Arch Ophthalmol 1997 Oct;115(10):1275.
- Williamson TH. Central retinal vein occlusion: what's the story? Br J Ophthalmol. 1997 Aug;81(8):698-704. Review.
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