CT_PD: Counterfactual Thinking and Decision-making in Parkinson's Disease
Study Details
Study Description
Brief Summary
The aim of this research is to verify the ability of counterfactual thinking about medical decisions in individuals affected by Parkinson's Disease when compared to healthy individuals.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Cases Individuals diagnosed with Parkinson's Disease consecutively recruited at the beginning of rehabilitative treatment at the Istituto Auxologico Italiano, IRCCS, San Giuseppe Hospital (Italy). Concurrent neurological, neurodevelopmental (e.g., autism), motor or psychiatric disorders were exclusion criteria. |
Behavioral: Counterfactual Inference Test
All participants were asked to complete the Counterfactual Inference Test - CIT (McNamara et al., 2003), a neuropsychological test that measures the ability to produce counterfactual-derived inferences. Moreover, the decision-making ability will be specifically tested through ad-hoc questionnaire (i.e., the Decision-Making Questionnaire). Finally, all participants will be screened with an extensive neuropsychological assessment, particularly on executive functioning.
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| Controls Age-matched healthy individuals recruited outside the hospital through personal contacts of the researchers and word-of-mouth. |
Behavioral: Counterfactual Inference Test
All participants were asked to complete the Counterfactual Inference Test - CIT (McNamara et al., 2003), a neuropsychological test that measures the ability to produce counterfactual-derived inferences. Moreover, the decision-making ability will be specifically tested through ad-hoc questionnaire (i.e., the Decision-Making Questionnaire). Finally, all participants will be screened with an extensive neuropsychological assessment, particularly on executive functioning.
|
Outcome Measures
Primary Outcome Measures
- CIT score [Baseline]
Score at the Counterfactual inference test (CIT). The questionnaire is a four question forced choice test based on past research regarding factors that enhance counterfactual thinking. For each of the four questions, events experienced by two individuals are presented, and three response options are given. Only one option is the valid: the score is 1. For the not valid options, the score will be 0. Overall, the score range for the questionnaire is from 0 (worse performance) to 4 (best performance).
Secondary Outcome Measures
- Decision-making index [Baseline]
Score at the Decision-Making Questionnaire. The self-report questionnaire assesses the decision making ability according to 7 questions, with a 5-item Likert's scale. The overall score (i.e., the sum of the scores at all questions) can range from 7 (worse decision making strategy) to 35 (best decision making strategy).
Eligibility Criteria
Criteria
Inclusion criteria:
• Diagnosis of Parkinson's disease, according to the medical assessment performed by trained neurologists.
Exclusion Criteria:
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Diagnosis of Obstructive Sleep Apnea Syndrome, according to the clinical assessment;
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Concurrent neurological, neurodevelopmental (e.g., autism), motor, and/or psychiatric disorders;
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Dementia, according to the clinical/neuropsychological assessment.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | IRCCS Istituto Auxologico Italiano - Ospedale San Giuseppe | Piancavallo | VCO | Italy | 28824 |
Sponsors and Collaborators
- Istituto Auxologico Italiano
- Istituti Clinici Scientifici Maugeri SpA
Investigators
- Principal Investigator: Sofia Tagini, PhD, IRCCS Istituto Auxologico Italiano
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 21C129