Effect of Selected Types of Breathing Exercises on Different Outcome Measures in Covid-19 Patients

Sponsor
Basma Mosaad Abd-elrahman Abushady (Other)
Overall Status
Completed
CT.gov ID
NCT05753293
Collaborator
(none)
60
1
2
4.8
12.4

Study Details

Study Description

Brief Summary

Coronavirus disease 2019 (COVID-19) infection leads to significant respiratory that have negative impact on function and quality of life (QoL). Breathing exercises are effective and important in patients with COVID-19.

Condition or Disease Intervention/Treatment Phase
  • Other: breathing exercise
N/A

Detailed Description

Coronavirus disease 2019 (COVID-19) infection leads to significant respiratory symptoms that have negative impact on function and quality of life (QoL). Breathing exercises are effective and important in patients with COVID-19.

This study aimed to evaluate the effect of Buteyko breathing versus Bhastrika Pranayama on different outcome measures in COVID-19 Patients.

Sixty patients of both genders with age range from 40-50 years old were recruited from El Khankah Centeral Hospital with positive nasopharyngeal swab samples and presence of ground-glass opacification in their chest computed tomography scan (CT-scan). Patients were assigned randomly into two groups A & B and took their medications. Group A received traditional physical therapy program (mobility exercises and Postural drainage) with Bhastrika Pranayama breathing exercise. Group B received traditional physical therapy program with Buteyko breathing exercise. Patients were assessed by Modified Borg Dyspnea Scale (MBS), blood samples (levels of CRP and d-dimer), six-minute walk test (6MWT), Pittsburgh Sleep Quality Index (PSQI), 36-Item Short-Form Health Survey (SF-36) Questionnaire.

Study Design

Study Type:
Interventional
Actual Enrollment :
60 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
Sixty patients of both genders with age range from 40-50 years old will be recruited from El Khankah Centeral Hospital with positive nasopharyngeal swab samples and presence of ground-glass opacification in their chest computed tomography scan (CT-scan) will be assigned randomly into two groups A & B and take their medications.Sixty patients of both genders with age range from 40-50 years old will be recruited from El Khankah Centeral Hospital with positive nasopharyngeal swab samples and presence of ground-glass opacification in their chest computed tomography scan (CT-scan) will be assigned randomly into two groups A & B and take their medications.
Masking:
None (Open Label)
Primary Purpose:
Prevention
Official Title:
Effect of Selected Types of Breathing Exercises on Different Outcome Measures in Covid-19 Patients
Actual Study Start Date :
May 1, 2022
Actual Primary Completion Date :
Jul 22, 2022
Actual Study Completion Date :
Sep 25, 2022

Arms and Interventions

Arm Intervention/Treatment
Experimental: Bhastrika pranayama

done in sitting posture and the following instructions: The back must be kept straight and shoulder muscles should be kept relaxed, patient was asked to close the right nostril with right thumb and to bring right elbow to the level of right shoulder. To close the eyes, inhale and exhale through left nostril-first slowly, then a little faster, The subject was asked to do the above steps about 20-25 times, (Then the subject was asked to take a long breath in and retain it for as long as possible, This is one cycle of Bhastrika pranayama. The subject has to repeat this cycle by closing left nostril and breathing through right nostril.

Other: breathing exercise
Buteyko breathing technique developed to control hyperventilation and anxiety which leads to shortness of breath. It uses series of exercises to teach patients to breathe less deeply and less rapidly /Bhastrika "Bellow Breathing" is diaphragmatic breathing - deep breathing involving the diaphragm rather than the accessory muscles. Regulated pranayama exercises require inhalation, maintaining isometric contraction of respiratory muscles and forceful expiration. These techniques will strengthen respiratory muscles
Other Names:
  • Bhastrika pranayama . Buteyko breathing exercise
  • Experimental: Buteyko breathing exercise

    Step 1 beginning control pause (CP) the patient inhales and then exhales through the nose and then holds their breath until the point they feel either the first clear and distinct desire to breath or involuntary movement or jerk coming from diaphragm.Step 2 three to five minutes of relaxed reduced-volume breathing or slow breathing the patient gradually reduced their breathing until they feel a light lack of air. they sustain these while staying relaxed. Step 3 maximum pause (MP) the maximum pause begins with gentel inhalation and exhalation. Then the breath is held as long as possible but not to the point of severe discomfort. Step 2 and step 3 are then repeated up to 5 times. Final control pause: same as step 1.

    Other: breathing exercise
    Buteyko breathing technique developed to control hyperventilation and anxiety which leads to shortness of breath. It uses series of exercises to teach patients to breathe less deeply and less rapidly /Bhastrika "Bellow Breathing" is diaphragmatic breathing - deep breathing involving the diaphragm rather than the accessory muscles. Regulated pranayama exercises require inhalation, maintaining isometric contraction of respiratory muscles and forceful expiration. These techniques will strengthen respiratory muscles
    Other Names:
  • Bhastrika pranayama . Buteyko breathing exercise
  • Outcome Measures

    Primary Outcome Measures

    1. Modified Borg Scale to Measure dyspnea: [week]

      is a 0 to 10 rated numerical score used to measure dyspnea as reported by the patient with higher score indicates breathing problem.

    2. Blood Samples: [week]

      The blood samples will be collected before starting and at the end of the study to measure levels of CRP, d-dimer and CBC to test.

    3. The Six-minute walk test: [week]

      The six-minute walk test (6MWT) will be done pre & post exercise program.

    4. Pittsburgh Sleep Quality Index (PSQI) [week]

      The PSQI questionnaire was used to measure sleep quality using an 18-item scale containing seven items that included sleep quality, sleep duration, sleep latency, habitual sleep efficiency, sleep disturbance, use of sleeping medications, and daytime dysfunction. Each dimension scored between 0-3, with a total score ranging from 0-21, and a higher score indicating lower sleep quality

    5. The 36-Item Short-Form Health Survey (SF-36) Questionnaire [week]

      The SF-36 is a 36-item scale, which measures eight domains of health status: physical functioning (10 items); physical role limitations (four items); bodily pain (two items); general health perceptions (five items); energy/vitality (four items); social functioning (two items); emotional role limitations (three items) and mental health (five items) the scores are weighted sums of the questions in each section. Scores range from 0 - 100 Lower scores = more disability, higher scores = less disability

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    40 Years to 50 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion criteria:
    • Their age ranged from 40 to 50years old.

    • with confirmed COVID-19 by positive nasopharyngeal swab samples and presence of ground-glass opacification in their chest computed tomography scan (CT-scan).

    • Moderate hospitalized covid-19 patient.

    • full consciousness and oriented.

    • BMI 20-25 kg/m2.

    Exclusion criteria:
    • presence of any type of musculoskeletal disorder prohibits the patient from participating in the study

    • history of chronic diseases as (diabetes, hypertension and heart diseases)

    • Any type of obvious clinically mental or cognitive impairment.

    • History of previous other respiratory disease.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Faculty of Physical Therapy Cairo University Giza Egypt 11595

    Sponsors and Collaborators

    • Basma Mosaad Abd-elrahman Abushady

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Basma Mosaad Abd-elrahman Abushady, Master student at Department of Physical Therapy for Cardiovascular, Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Cairo University
    ClinicalTrials.gov Identifier:
    NCT05753293
    Other Study ID Numbers:
    • P.T.REC/012/004298
    First Posted:
    Mar 3, 2023
    Last Update Posted:
    Mar 3, 2023
    Last Verified:
    Feb 1, 2023
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Mar 3, 2023