Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID- 19 Patients
Study Details
Study Description
Brief Summary
This study will be conducted on eighty patients of both sexes with age ranging from 35 to 45years. The will be recovered from COVID-19 infection with chest symptoms. They will be selected from Nasr city police authority hospital. They will be randomly assigned into 3 equal groups.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
This study will be conducted on eighty patients of both sexes with age ranging from 35 to 45years. The will be recovered from COVID-19 infection with chest symptoms. They will be selected from Nasr city police authority hospital. They will be randomly assigned into 3 equal groups.
Participants will be assigned into 3 groups equal in number (group A, group B, group C)
Group A (Respiratory Training Group) : It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive respiratory training for 6 weeks.
Group B : (Aerobic Training Group) : It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive aerobic training for 6 weeks
Group C : (control group) :It will include 20 patients of both sexes, recovered from COVID-19 infection on medical drugs only will receive no exercise as control group.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: Group A (Respiratory Training Group) It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive respiratory training for 6 weeks. |
Other: Respiratory Training
Respiratory training in form of :
Diaphragmatic breathing,Segmental breathing, Incentive spirometer:
|
| Active Comparator: Group B : (Aerobic Training Group) It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive aerobic training for 6 weeks |
Other: Aerobic training
aerobic exercises are customized according to the patient's underlying disease and residual dysfunction. These exercises will include walking on treadmill. After an initial, 5-minute warm-up phase performed on the treadmill at a low load, each endurance training session lasted 30 minutes and ended with 5-minute recovery and relaxation phase. A total of 3-5 sessions are carried out per week. Patients who are prone to fatigue should perform intermittent exercises
|
| No Intervention: Group C : (control group) It will include 20 patients of both sexes, recovered from COVID-19 infection on medical drugs only will receive no exercise as control group. |
Outcome Measures
Primary Outcome Measures
- Complete blood picture [change from baseline at 6 weeks]
A venous blood sample will be taken to be analyzed in the laboratory
- Arterial blood gases [change from baseline at 6 weeks]
arterial blood sample will be assessed
- 6-minute walk Distance [change from baseline at 6 weeks]
patient will be instructed to walk as fast as long as possible, in a 30 meters obstacle- free corridor, limited by turnaround cones. Standardized verbal encouragement will be given every minute. After 6 min, patient will be instructed to stop, and the total distance will be measured, rounding to the nearest meter.
- Breath-hold test [change from baseline at 6 weeks]
A rough index of cardiopulmonary reserve measured by the length of time that a person can voluntarily stop breathing; normal duration is 30 seconds or longer; diminished cardiac or pulmonary reserve is indicated by a duration of 20 seconds or less.
- Oxygen saturation [change from baseline at 6 weeks]
Percentage of haemoglobin saturated with oxygen measured by pulse oximeter
- Borg Dyspnea Scale score [change from baseline at 6 weeks]
It is a 0 to 10 rated numerical score used to measure dyspnea as reported by the patient during six minute walk test
Secondary Outcome Measures
- Maximum oxygen consumption [change from baseline at 6 weeks]
Maximum oxygen consumption(VO2 max): Results of (6MWT) was used to calculate Vo2 max by using Cahalin equation as follows; Vo2 max = 0.03x distance in meters +3.98, in which distance is obtained from (6MWT)
Eligibility Criteria
Criteria
Inclusion Criteria:
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Patients recovered from COVID -19 infection.
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Patients with body mass index 25 - 35 kg/m2
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Patients previously diagnosed with chest symptoms of COVID- 19 infection.
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Patients' body temperature less than 37.5
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Blood oxygen saturation ≥95%
Exclusion Criteria:
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Smokers
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Patients with Myocardial infarction
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Patients with diabetes.
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Patients with autoimmune disease.
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Patients with positive COVID -19 infection.
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Patients with previous chest diseases
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a heart rate of >100 bpm
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a blood pressure of <90/60 mmHg or >140/90 mmHg
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a blood oxygen saturation of ≤95%
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other diseases that are not suitable for exercise (osteoarthritis knee - stroke patients, etc)
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Police hospital-Nasr city | Cairo | Egypt | 002 |
Sponsors and Collaborators
- Cairo University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- MAHA2020