The Impact Evaluation of the COVID-19 Prevention on Risk Factors of HIV and Sexually Transmitted Comorbidity

Sponsor

National Taiwan University (Other)

Overall Status

Recruiting

CT.gov ID

NCT05188456

Collaborator

Ministry of Science and Technology, Taiwan (Other)

1,200

Enrollment

Location

18.5

Anticipated Duration (Months)

64.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This is a cross-sectional research. The Protection Motivation Theory (PMT) was applied as theoretical framework to analyze correlation of prevention knowledge, prevention intentions and anxiety, and prevention behavior of COVID-19 and HIV risk feature and behavior and stigma of people living with HIV/AIDS (PLWHA), and HIV high-risk groups. Purposive and snowball sampling will be applied to recruit participant who visit hospital, HIV/AIDS related institutions, and social media platforms. The investigators expect that the outcome could reveal the relationship of cognition and attitude of COVID-19 to HIV prevention and treatment.

Condition or Disease	Intervention/Treatment	Phase
COVID-19 Pandemics Human Immunodeficiency Virus

Detailed Description

The prevention strategies can effectively block the spread of Coronavirus disease (Coronavirus disease 19; COVID-19), and at the same time may indirectly reduce or increase the risk behaviors and factors of Human Immunodeficiency Virus (HIV) and sexually transmitted comorbidities. The main purpose of this research is to apply the Protection Motivation Theory (PMT) as the framework to analyze COVID-19 prevention knowledge, COVID-19 prevention intentions and anxiety level, and COVID-19 prevention behavior and HIV risk behavior and risk factors of people living with HIV/AIDS (PLWHA) and HIV high-risk groups. The cross-sectional research method was adopted, and the subjects included the northern, central, southern, and eastern regions of Taiwan.About 6,00 PLWHA and 6,00 high-risk groups will be recruited. The information of recruitment will be disseminated through the AIDS designated medical institutions and related institutions, and social media, Snowball recruitment of interviewees will also be used. After completing the online questionnaire, the structural equation modeling (SEM) will be applied to test the good of fit of the theory model and to explain the structural relationship between COVID-19 prevention knowledge, attitudes, behaviors and HIV risk factors. The relationship with the above variables and stigma also been discussed. In addition to verifying the theories proposition of PMT, the research results also contribute to the prevention and treatment of HIV high-risk groups, and provide important references for prevention strategies for susceptible groups during the epidemic of emerging infectious diseases in the future.

Study Design

Study Type:

Observational [Patient Registry]

Anticipated Enrollment :

1200 participants

Observational Model:

Case-Only

Time Perspective:

Cross-Sectional

Official Title:

The Impact Evaluation of the COVID-19 Prevention Knowledge, Attitude, and Practice on Risk Factors of HIV and Sexually Transmitted Comorbidity: Application of Protection Motivation Theory

Actual Study Start Date :

Jan 13, 2022

Anticipated Primary Completion Date :

Jun 30, 2023

Anticipated Study Completion Date :

Jul 31, 2023

Outcome Measures

Primary Outcome Measures

COVID-19 prevention knowledge [Through study completion, an average of one and half year]
The questionnaire of COVID-19 prevention knowledge will be used to measure the knowledge level.
COVID-19 prevention intention and anxiety [Through study completion, an average of one and half year]
The questionnaire of COVID-19 prevention intention and anxiety will be used to measure the attitude level.
COVID-19 prevention behavior [Through study completion, an average of one and half year]
The questionnaire of COVID-19 prevention behavior will be used to measure the behavior level.
Stigma [Through study completion, an average of one and half year]
The questionnaire of stigma will be used to measure the stigma level of HIV infected people.
HIV risk factor and behavior [Through study completion, an average of one and half year]
The questionnaire of HIV risk factor and behavior will be used to measure the risk condition during COVID-19 era.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria for HIV/AIDS participants:

Participants who diagnosed with HIV/AIDS.
Age over 18 years old.
Participants who can read and communicate.

Exclusion Criteria for HIV/AIDS participants:

Participants who can't read and communicate.

Inclusion Criteria for HIV high risk group:

Participants who have experienced unsafe sex, regardless of their gender orientation, such as those who describe themselves as men who have sex with men (MSM), heterosexuals, transgender, sex workers, etc.
Injecting Drug User(IDU)
Age over 18 years old.
Participants who can read and communicate.