COVID-19 - SARS-CoV-2 Community Contamination in Children and Adults (Dyn3CEA_Nosocor)

Sponsor

Hospices Civils de Lyon (Other)

Overall Status

Completed

CT.gov ID

NCT04664296

Collaborator

(none)

Enrollment

Location

Actual Duration (Months)

23.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Unlike other respiratory viruses such as influenza and Respiratory Syncytial Virus (RSV) where the child is the essential reservoir and central vector of intrafamilial contamination, the child is likely to be a small player in the transmission of Severe Acute Respiratory Syndrome CoronaVirus 2 (SRAS-CoV2) infection. This study aims to describe the age category of the first contact, within 14 days before the appearance of the first symptoms of the index case in order to describe the age categories of this first contaminant, globally, in the group of children and finally in the group of adults. This work is intended to provide food for discussion and to justify the distancing and containment measures imposed on children when their isolation has a deleterious impact that has now been established for some children.

Condition or Disease	Intervention/Treatment	Phase
Infection Viral	Other: Review of medical patient file Other: Phone call interview

Study Design

Study Type:

Observational

Actual Enrollment :

72 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

Epidemiology of CoV-2 SARS Infections: Dynamics of Community Contamination in Children and Adults

Actual Study Start Date :

Dec 21, 2020

Actual Primary Completion Date :

Mar 23, 2021

Actual Study Completion Date :

Mar 23, 2021

Arms and Interventions

Arm	Intervention/Treatment
Children Hospitalized children, 0 to 17 years of age, 25 subjects, consecutive sample survey	Other: Review of medical patient file Review of medical patient file, including patient tracing, brief summary of the disease course, barrier gestures, social distancing.
Adults Hospitalized adults, 18 years and above, 50 matched subjects	Other: Phone call interview less than 15 minutes phone call

Arm

Intervention/Treatment

Children

Hospitalized children, 0 to 17 years of age, 25 subjects, consecutive sample survey

Other: Review of medical patient file

Review of medical patient file, including patient tracing, brief summary of the disease course, barrier gestures, social distancing.

Adults

Hospitalized adults, 18 years and above, 50 matched subjects

Other: Phone call interview

less than 15 minutes phone call

Outcome Measures

Primary Outcome Measures

Percentage of possible contaminants, adults, adolescents and children with Covid-19 [at inclusion]
To describe the age category of the 1st possible contaminant in the index case to show the preponderance of possible adult and adolescent contaminants in the SARS-Cov-2 contamination. Percentage of possible contaminants, adults, adolescents and children, in matched children and adults with Covid-19.

Eligibility Criteria

Criteria

Ages Eligible for Study:

0 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Children after hospitalized in Hospices Civils de Lyon with Polymerase Chain Reaction (PCR) positive SARS-CoV2,
Adults hospitalized in Hospices Civils de Lyon and included in the NOSO-COR study with matching criteria described below.

Matching will be performed on family age characteristics and on the period of contamination included in the containment period to minimize bias, and if possible frequency matching according to admission in Intensive Care Unit ICU/Pediatric Intensive Care Unit (PICU), and to family structure (n of children / n of adults in the family).

Exclusion Criteria:

Any patient suspected of nosocomial infection.
Any patient death during the Covid-19 infection.
Any adult patient without children living home.
Opposition to participate.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Service de Reanimation Pediatrique	Lyon	Rhone	France	69003

Sponsors and Collaborators

Hospices Civils de Lyon

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Hospices Civils de Lyon

ClinicalTrials.gov Identifier:

NCT04664296

Other Study ID Numbers:

69HCL20_1100

First Posted:

Dec 11, 2020

Last Update Posted:

Apr 26, 2021

Last Verified:

Apr 1, 2021

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Infections

Virus Diseases

Study Results

No Results Posted as of Apr 26, 2021