COVID-19 and Vitamin D: Length of Hospital Stay and Mortality

Sponsor

Yuksek Ihtisas University (Other)

Overall Status

Completed

CT.gov ID

NCT05221983

Collaborator

Ankara City Hospital Bilkent (Other)

168

Enrollment

Location

2.9

Actual Duration (Months)

58.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The lack of a pharmacological treatment in the COVID-19 pandemic has pushed scientists to search for this issue. Maintaining optimal health is parallel to adequate and balanced nutrition. In this context, can the protective properties of vitamin D play an important role in this pandemic? brought with it the thought. In this study, it was aimed to examine the effect of vitamin D on mortality and hospital stay in COVID-19 disease.

Condition or Disease	Intervention/Treatment	Phase
COVID-19 Pandemic Vitamin D Deficiency

Detailed Description

This research was conducted to examine the effect of vitamin D on mortality and hospital stay in COVID-19 disease. For this, the approval of the Ministry of Health and then the ethics committee was obtained. For this reason, patients with positive PCR tests and hospitalized patients with vitamin D levels in their biochemistry were included in the study.

The data of the patients were obtained from the medical records. Information such as age, gender, comorbidities, length of hospital stay, vitamin D level were included in the study. According to the statistical analyzes obtained from these data, it has been shown that vitamin D level has no effect on mortality and hospital stay in COVID-19 disease.

Study Design

Study Type:

Observational

Actual Enrollment :

168 participants

Observational Model:

Case-Only

Time Perspective:

Retrospective

Official Title:

Vitamin D Level: Reflections of a Public Health Issue in the COVID-19 Pandemic. Does it Affect Mortality and Length of Hospital Stay?

Actual Study Start Date :

Aug 21, 2021

Actual Primary Completion Date :

Nov 9, 2021

Actual Study Completion Date :

Nov 16, 2021

Arms and Interventions

Arm	Intervention/Treatment
Patients with COVID-19 + with vitamin D levels Patients with COVID-19 + and vitamin D levels were included in the study retrospectively. Vitamin D level was categorized into 3 groups as inadequacy, deficiency and normal from medical records. No intervention was made.

Outcome Measures

Primary Outcome Measures

Level of Vitamin D [1 month later]
Vitamin D levels of patients with a diagnosis of COVID-10. These results were categorized at the level of deficiency/insufficiency/normal.
Relationship between vitamin D level and mortality [1 month later]
Relationship between survival and death by categorized vitamin D level.
Relationship between vitamin D level and hospital stay [1 month later]
Length of hospital stay by categorized vitamin D level.

Secondary Outcome Measures

Effects of additional diseases (Diabetes mellitus, hypertension, etc.) on hospital stay and mortality [1 month later.]
Evaluation of the impact of comorbidities on survival during COVID-19 disease.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

COVID-19 PCR (Polymerase Chain Reaction) test positive
Vitamin D level in biochemical parameters
Adult patients hospitalized for COVID-19

Exclusion Criteria:

-Patients using drugs that may affect vitamin D absorption, such as corticosteroids, cholesterol-lowering agents, phenobarbital and phenytoin-containing agents