COVIDANOSMIA: Study Evaluating the Olfactory Recovery of Anosmia Post COVID-19 by Olfactory Rehabilitation Assisted by Web-application
Study Details
Study Description
Brief Summary
Anosmia is a symptom present in 40 to 80% of patients and usually only lasts 1 to 2 weeks. However, in nearly one in five patients, it can last beyond or even several months with consequences in terms of undernutrition and depression. However, olfactory rehabilitation is a technique validated in post-infectious anosmia since 2014 and recommended by international learned societies to accelerate recovery with nearly 63% improvement in anosmia In the context of the health crisis linked to the coronavirus, approximately 1 million French people will have persistent anosmia following an infection with COVID-19. A web-application to support the olfactory coaching of anosmic patients and help with follow-up seems relevant to promote recovery and the proper conduct of this coaching.
covidanosmie.fr is a web application dedicated to olfactory rehabilitation, accessible free of charge.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| users Users of web-application |
Device: Web-application
support for olfactory coaching consisting of the inhalation of fragrant essential oils.
|
Outcome Measures
Primary Outcome Measures
- Evaluation of the rate of patients presenting an improvement in their anosmia [16 weeks]
Number of patients with an improvement in anosmia (increase of at least 1 point on the visual analogue scale 0-10) on the number of users
Secondary Outcome Measures
- Evaluation of the time until recovery of at least 1point in 10 (Visual Analog Scale) from anosmia, [16 weeks]
Time between the date of first use of the application and the date of recovery of at least one point of anosmia
- Assessment of the duration of anosmia [16 weeks]
Time between the date of diagnosis or onset of anosmia and the date of final recovery
- Evaluation of the recovery of at least one point in 10 (Visual Analog Scale) depending on the oils [16 weeks]
Evolution of the VAS according to the different oils, proportion of patients with an increase of at least 1 point in anosmia on a visual analog scale (from 0 no smell to 10 normal smell) of each oil
Eligibility Criteria
Criteria
Inclusion Criteria:
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Post-COVID anosmia lasting more than 1 month
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Consent to the use of data via the application
Exclusion Criteria:
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Other causes of anosmia than COVID
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Contraindication to olfactory coaching (allergy to one of the aromatic oils)
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Minor
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | ILC | Le Mans | France | 72000 |
Sponsors and Collaborators
- Weprom
- Kelindi
- Centre National de la Recherche Scientifique, France
- Hospital of Tours
Investigators
- Study Director: Fabrice DENIS, MD, Weprom
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- WP-2020-06