A Cross-sectional Survey of Colorectal Cancer Patients in Different Age Groups

Sponsor

Wang Guiyu (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT06145230

Collaborator

(none)

430

Enrollment

Location

Anticipated Duration (Months)

35.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.

Condition or Disease	Intervention/Treatment	Phase
Colorectal Cancer Age Problem

Detailed Description

Colorectal cancer is one of the common and highly prevalent malignant tumors of the gastrointestinal system. Previous studies have found that there may be some differences in disease characteristics and prognosis of colorectal cancer patients at different ages, such as patients with early-onset colorectal cancer (age <50 years) tend to have a worse prognosis than patients with late-onset colorectal cancer (age ≥50 years). However, existing studies on the characteristics of colorectal cancer patients at different ages are not well studied to answer the differences between these patients and develop targeted diagnostic and treatment strategies. Cross-sectional survey research, which uses survey research to collect data on a characteristic group over a certain period of time and statistically analyzes the data to obtain the characteristics of a certain disease or a certain treatment strategy, is a more mature approach that is particularly suitable for the questions that need to be answered in this study. Investigators found that no similar studies have been registered and conducted by searching the official websites of the China Clinical Research Registry and Clinical Trial, and there is a lack of research data on the Chinese population. Therefore, investigators believe there is an urgent need for a cross-sectional survey to study the symptomatic characteristics, family history, and pathologic features of colorectal cancer patients. This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.

Study Design

Study Type:

Observational

Anticipated Enrollment :

430 participants

Observational Model:

Cohort

Time Perspective:

Cross-Sectional

Official Title:

A Cross-sectional Survey of Symptomatic Characteristics, Family History and Pathologic Features of Colorectal Cancer Patients in Different Age Groups

Anticipated Study Start Date :

Dec 1, 2023

Anticipated Primary Completion Date :

Oct 1, 2024

Anticipated Study Completion Date :

Dec 1, 2024

Arms and Interventions

Arm	Intervention/Treatment
Under 60 group Colorectal cancer paitents aged under 60 years old ( do not include 60 years old)
60-69 group Colorectal cancer paitents aged 60-69 years old
70-79 group Colorectal cancer paitents aged 70-79 years old
80 and over group Colorectal cancer paitents aged 80 and over 80 years old

Outcome Measures

Primary Outcome Measures

Characteristics of clinical symptoms [2023.12-2024.10]
Comparison of the characteristics of clinical symptoms in patients of different ages;
Family history [2023.12-2024.10]
Comparison of the probability of having a family history in patients of different age stages;
Pathological characteristics [2023.12-2024.10]
Comparison of pathological characteristics of patients at different age stages;

Secondary Outcome Measures

Risk factors [2024.09-2024.10]
Analysis of risk factors for stage progression in colorectal cancer patients

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Adults aged 18 years and older with a pathologic diagnosis of colorectal cancer;
Undergoing surgical treatment of the primary lesion;
Voluntary participation of patients.

Exclusion Criteria:

Do not agree to participate in the survey or withdraw informed consent
Patients did not receive surgical treatment or did not undergo pathologic examination