CT Scores Predict Mortality in 2019-nCoV Pneumonia

• Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (Other)
• Overall Status: Completed
• CT.gov ID: NCT04284046
• Collaborator: (none)
• Enrollment: 39
• Location: 1
• Actual Duration (Days): 18
• Patients Per Site Per Month: 65.9

Study Details

Study Description

Brief Summary

While 2019-nCoV nucleic acid swab tests has high false positives rate, How to diagnose 2019-nCoV pneumonia and predict prognosis by CT is very important.In this retrospective single-center study, we consecutively included suspected 2019-nCoV pneumonia critical cases in the intensive care unit of Wuhan third hospital from January 31, 2020 to February 16, 2020. The cases were confirmed by real-time RT-PCR, and all patients were evaluated with CT, cutoff values were obtained according to the Yoden index, and were divided into high CT score group and low CT score group. Epidemiological, demographic, clinical, and laboratory data were collected.

Condition or Disease	Intervention/Treatment	Phase
CT Scores Predict Mortality in 2019-nCoV Pneumonia	Other: CT score

Study Design

• Study Type: Observational
• Actual Enrollment: 39 participants
• Observational Model: Cohort
• Time Perspective: Retrospective
• Official Title: CT Scores Predict Mortality in 2019-nCoV Pneumonia
• Actual Study Start Date: Jan 31, 2020
• Actual Primary Completion Date: Feb 18, 2020
• Actual Study Completion Date: Feb 18, 2020

Arms and Interventions

Arm	Intervention/Treatment
High CT score	Other: CT score; CT score = normal lung tissue (%) ×1 + GGO (%) ×2 + consolidation (%) ×3
Low CTscore	Other: CT score; CT score = normal lung tissue (%) ×1 + GGO (%) ×2 + consolidation (%) ×3

Outcome Measures

Primary Outcome Measures

1. 7-day mortality [7-day]

Eligibility Criteria

Criteria

• Ages Eligible for Study: N/A and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• all patients suspected of 2019 novel coronavirus infection.

Exclusion Criteria:

• patients' data are not available.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Wuhan third hospital	Wuhan	Hubei	China

Sponsors and Collaborators

• Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Ruilan Wang, PhD, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
• ClinicalTrials.gov Identifier: NCT04284046
• Other Study ID Numbers: CT2019-nCoV
• First Posted: Feb 25, 2020
• Last Update Posted: Feb 25, 2020
• Last Verified: Feb 1, 2020

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Pneumonia

Study Results

No Results Posted as of Feb 25, 2020