The Study of Bacteriology and Pathogen Drug Sensitivity of Chronic Dacryocystitis

• Sponsor: Sun Yat-sen University (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT03216642
• Collaborator: (none)
• Enrollment: 100
• Location: 1
• Anticipated Duration (Months): 9
• Patients Per Site Per Month: 11.1

Study Details

Study Description

Brief Summary

An observational study was designed to research the bacteriology and pathogen drug sensitivity of chronic dacryocystitis in China and optimize antibiotic therapy.

Condition or Disease	Intervention/Treatment	Phase
Dacryocystitis; Bacteriology	Diagnostic Test: bacterial culture and analysis

Detailed Description

For patients diagnosed with chronic dacryocystitis，we will collect the secretions after lacrimal passage irrigation, note the characters of the secretions and send the secretions for bacteria culture, analysis and pathogen drug sensitivity.

Study Design

• Study Type: Observational [Patient Registry]
• Anticipated Enrollment: 100 participants
• Observational Model: Case-Only
• Time Perspective: Other
• Official Title: The Study of Bacteriology and Pathogen Drug Sensitivity of Chronic Dacryocystitis
• Actual Study Start Date: Jul 17, 2017
• Anticipated Primary Completion Date: Apr 17, 2018
• Anticipated Study Completion Date: Apr 17, 2018

Outcome Measures

Primary Outcome Measures

1. Bacterial agents [2 weeks]

   Specimens will be collected after irrigation of the lacrimal passage and be sent for bacterial culture and bacterial analysis.

Secondary Outcome Measures

1. Sensitivity test [2 weeks]

   The drugs tested include Penicilin, Amikacin, Azithromycin, Cefoxitin, Levofloxacin，Ofloxacin, Cefuroxime and Tobramycin.

2. The colour of lacrimal sac secretion [2 weeks]

   The colour of lacrimal sac secretion will be identified by the doctor during the irrigation of the lacrimal passage.

3. The character of lacrimal sac secretion [2 weeks]

   The lacrimal sac secretion will be classified as mucus or pus.

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 70 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

1. Diagnosed with chronic dacryocystitis

2. No involvement in other drug experiment in the past 1 week

Exclusion Criteria:

1. Can not cooperate the specimen collection

2. With any other eye disease

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Clinical Research Center	Guangzhou	Guangdong	China	510000

Sponsors and Collaborators

• Sun Yat-sen University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Wang Zhichong, cornea department chief, Sun Yat-sen University
• ClinicalTrials.gov Identifier: NCT03216642
• Other Study ID Numbers: 2017019
• First Posted: Jul 13, 2017
• Last Update Posted: Jul 27, 2017
• Last Verified: Jul 1, 2017

• Individual Participant Data (IPD) Sharing Statement: Undecided
• Plan to Share IPD: Undecided
• Keywords provided by Wang Zhichong, cornea department chief, Sun Yat-sen University: Dacryocystitis; Bacteriology; Microbial Sensitivity Tests
• Additional relevant MeSH terms: Dacryocystitis; Hypersensitivity; Anti-Bacterial Agents

Study Results

No Results Posted as of Jul 27, 2017