DONATION-OB: Decrease Artery Occlusion by Distal Radial Arterial Cannulation, Observational Study
Study Details
Study Description
Brief Summary
The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications. Transradial access (TRA) reduces complications among patients undergoing percutaneous coronary procedures but is reported with the complication of radial artery occlusion (RAO) that limits the radial artery for future needs. Distal radial access (dTRA) has recently gained global popularity as an alternative access route for vascular procedures. Among the benefits of dTRA are the low risk of entry site bleeding complications, the low rate of radial artery occlusion, and improved patient and operator comfort. This study aims to reveal the feasibility and safety of dTRA and routine TRA procedures in acute coronary syndrome patients. The primary endpoints are forearm radical occlusion rate and major adverse cardiovascular events (MACEs) in the two groups. Investigators conduct this retrospected analysis to demonstrate the difference of the two procedure of Cannulation.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| dTRA group Investigators perform percutaneous coronary intervention by dTRA for patients |
Procedure: Radial Artery Approach
dTRA or conventional TRA for radical artery approach
|
| TRA group Investigators perform percutaneous coronary intervention by conventional TRA for patients |
Procedure: Radial Artery Approach
dTRA or conventional TRA for radical artery approach
|
Outcome Measures
Primary Outcome Measures
- Forearm radical [2 years]
Doppler ultrasound to determine whether patients suffer forearm radial occlusion
- MACEs [2 years]
Major Adverse Cardiovascular Events, including cardiovascular death, myocardial infarction and heart failure.
Eligibility Criteria
Criteria
Inclusion Criteria:
- presence of a pulse in the snuffbox
Exclusion Criteria:
-
Absence of pulse
-
Ultrasound indication of arterial occlusion or severe calcification
-
Severe forearm artery malformation
-
Patients with severe liver and renal failure, or abnormal coagulation function
-
Established cardiogenic shock
-
History of previous coronary artery bypass grafting and radial artery use.
-
Raynaud's disease in the medical history
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Shenzhen People's hospital | Shenzhen | Guangdong | China | 518000 |
Sponsors and Collaborators
- Shenzhen People's Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- DONATION-OB