Decrease in Temperature as a Pagtonomic Sign by Scorpion Sting

• Sponsor: Mexican Red Cross (Other)
• Overall Status: Completed
• CT.gov ID: NCT03622125
• Collaborator: Instituto Bioclon S.A. de C.V. (Industry)
• Enrollment: 184
• Location: 1
• Actual Duration (Months): 2.3
• Patients Per Site Per Month: 78.9

Study Details

Study Description

Brief Summary

The scorpion sting is a medical disease, for the signs and symptoms presented; Sometimes patients do not know the animal that causes these symptoms; the bibliography marks the decrease in temperature as a sign to be presented.

Condition or Disease	Intervention/Treatment	Phase
Scorpion Stings	Diagnostic Test: Vital signs

Detailed Description

The scorpion sting is a medical emergency where 184 patients from the state of Guanajuato were divided into 2 groups according to the type of antivenom administered, the dose of antivenom were at the discretion of the attending physician, Birmex (n = 117) and Alacramyn (n = 67) for the temperature record of the site of sting and other vital signs, this to compare it with the bibliography as a pathognomonic sign.

Study Design

• Study Type: Observational
• Actual Enrollment: 184 participants
• Observational Model: Case-Control
• Time Perspective: Cross-Sectional
• Official Title: Decrease in Temperature by Scorpion Sting: a Pagtonomic Sign
• Actual Study Start Date: May 20, 2017
• Actual Primary Completion Date: Jun 15, 2017
• Actual Study Completion Date: Jul 30, 2017

Arms and Interventions

Arm	Intervention/Treatment
1 Patients who apply anti-scorpion venom serum Birmex at the discretion of the attending physician were given vital signs.	Diagnostic Test: Vital signs; Axillary temperature sampling, at the site of the scorpion sting and the contralateral site with infrared thermometer, and heart rate, respiratory rate and blood pressure on admission, 30 minutes after applying the vial and the medical discharge
2 Patients who apply anti-scorpion venom serum Alacramyn at the discretion of the attending physician were given vital signs.	Diagnostic Test: Vital signs; Axillary temperature sampling, at the site of the scorpion sting and the contralateral site with infrared thermometer, and heart rate, respiratory rate and blood pressure on admission, 30 minutes after applying the vial and the medical discharge

Outcome Measures

Primary Outcome Measures

1. Temperature change [0, 30 and 120 minutes]

   Temperature at the sting site, contralateral site and axillary in degrees celcius

Secondary Outcome Measures

1. Blood preasure [0, 30 and 120 minutes]

   Systolic and diastolic in mmHg

2. Heart rate [0, 30 and 120 minutes]

   Beats per minute

3. Respiratory rate [0, 30 and 120 minutes]

   Breaths per minute

Eligibility Criteria

Criteria

• Ages Eligible for Study: 3 Years to 90 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Scorpion sting

• All sex

• 3 - 90 ages

Exclusion Criteria:

• Application of ice at the sting site

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Cruz Roja Mexicana, Delegación León	León	Guanajuato	Mexico	37179

Sponsors and Collaborators

• Mexican Red Cross
• Instituto Bioclon S.A. de C.V.

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

• Isbister GK, Bawaskar HS. Scorpion envenomation. N Engl J Med. 2014 Jul 31;371(5):457-63. doi: 10.1056/NEJMra1401108. Review.

• Responsible Party: Josue Saul Almaraz Lira, Principal Investigator, Mexican Red Cross
• ClinicalTrials.gov Identifier: NCT03622125
• Other Study ID Numbers: CRM-Alacranes-2017
• First Posted: Aug 9, 2018
• Last Update Posted: Aug 15, 2019
• Last Verified: Aug 1, 2018

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Bites and Stings; Scorpion Stings

Study Results

No Results Posted as of Aug 15, 2019