Melodic Intonation Therapy for Tone Language Speakers

Sponsor
The Hong Kong Polytechnic University (Other)
Overall Status
Suspended
CT.gov ID
NCT04221386
Collaborator
(none)
40
1
2
6.9
5.8

Study Details

Study Description

Brief Summary

One of the traditional therapies for restoring the ability of speech in aphasic patients is Melodic Intonation Therapy (MIT), in which everyday phrases are taught in a singing-like manner. The suggested mechanism for speech recovery is that because of the sharing of brain resources for language and music, the regions normally reserved for singing can be trained to help compensate the speech functions originally subserved by the damaged regions. However, this therapy has primarily been applied to speakers of non-tone languages, in which prosodic features carry a more important role than pitch features in conveying meanings. It remains unknown whether MIT will be equally applicable for speakers of tone languages, in which pitch features likely play a more important role. Another uncertainty concerns whether the efficacy of MIT can be extended to patients with expressive speech impairment due to dementia. This pilot study aims to find out the efficacy of MIT for speech-impaired dementia patients in different verbal tasks. The results of this study will provide preliminary empirical evidence to establish the utility of MIT for Cantonese speakers in Hong Kong.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Melodic Intonation Therapy (MIT)
N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
40 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Double (Participant, Care Provider)
Primary Purpose:
Treatment
Official Title:
Melodic Intonation Therapy for Tone Language Speakers
Anticipated Study Start Date :
Aug 1, 2020
Anticipated Primary Completion Date :
Dec 31, 2020
Anticipated Study Completion Date :
Feb 28, 2021

Arms and Interventions

Arm Intervention/Treatment
Experimental: MIT group

Subjects will receive the developed Melodic Intonation Therapy.

Behavioral: Melodic Intonation Therapy (MIT)
Subjects will receive at least 6 MIT sessions in group of 3-5 subjects. In the sessions, experimenter will sing songs with the subjects. Songs used in the intervention are familiar to elderly and are rewritten and embedded with everyday phrases and vocabularies. The whole intervention will span 3-4 weeks.

No Intervention: Control group

Subjects will not receive any intervention.

Outcome Measures

Primary Outcome Measures

  1. Change in Aphasia Quotient (AQ) in Cantonese Aphasia Battery [within a week after procedure]

    Two subtests of the Cantonese Aphasia Battery (auditory comprehension & spontaneous speech) will be executed. Higher AQ means better performance in the respective areas. The minimum of AQ in each subtest is 0, and the maximum is 20.

Secondary Outcome Measures

  1. Change in latency and accuracy in picture naming task [within a week after procedure]

    In the computerized picture naming task, subjects are asked to name the objects they see in 52 pictures, within 5000 ms per picture. Visual stimuli of the task are black and white line-drawings. Responses are all recorded for analysis.

  2. Change in performance of semantic fluency task [within a week after procedure]

    In the computerized semantic fluency task, subjects are given 5 categories (e.g. animals) and asked to name as many members of the categories (e.g. cat, dog) as possible. For each category, they have one minute to respond. All the responses are recorded for analysis.

Eligibility Criteria

Criteria

Ages Eligible for Study:
50 Years to 100 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Early to moderate stage dementia patient

  • Normal hearing (hearing aid accepted)

  • Non-fluent speech (max. score of fluency in Cantonese Aphasia Battery spontaneous speech subtest = 6/10)

Exclusion Criteria:
  • Non-native Cantonese speaker

  • Illiterate

  • Aphasic patients

  • Subjects who receive other speech therapy during study

Contacts and Locations

Locations

Site City State Country Postal Code
1 Elderly homes Hong Kong Hong Kong

Sponsors and Collaborators

  • The Hong Kong Polytechnic University

Investigators

  • Principal Investigator: William Shi Yuan Wang, Ph.D., The Hong Kong Polytechnic University

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
The Hong Kong Polytechnic University
ClinicalTrials.gov Identifier:
NCT04221386
Other Study ID Numbers:
  • IZZKJ
First Posted:
Jan 9, 2020
Last Update Posted:
Apr 10, 2020
Last Verified:
Dec 1, 2019
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by The Hong Kong Polytechnic University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Apr 10, 2020