CANDO: Online Cognitive Behavioral Intervention Program for Hong Kong People With Depression

Sponsor
Hong Kong Baptist University (Other)
Overall Status
Recruiting
CT.gov ID
NCT04388800
Collaborator
Stockholm University (Other), Richmond Fellowship of Hong Kong (Other), Caritas Wellness Link - Tsuen Wan (Other), Dr. Chiu Siu Ning (Other), Innovation and Technology Fund for Better Living (Other)
400
1
3
41.9
9.5

Study Details

Study Description

Brief Summary

The purpose of this study is to develop a culturally and linguistically appropriate online cognitive behavioral intervention program-- with therapist guidance -- for Hong Kong Chinese adults suffering from major depressive disorder with mild to moderate depressive symptoms, and examine the effectiveness of this program in reducing their depressive symptoms and improving their mental health. The 3- and 6-month maintenance effect after 3 months and 6 months will also be tested.

Condition or Disease Intervention/Treatment Phase
  • Other: Confront and Navigate Depression Online (CANDO)
N/A

Detailed Description

Previous studies have demonstrated that online cognitive behavioral therapy can significantly reduce depressive symptoms and improve mental health for people with depression. This project will develop an online cognitive behavioral intervention program (including both an online platform and a smartphone application) for Hong Kong people with depression. Blended mode will be delivered service, which include 8-week online program, 2 face-to-face sessions and 2 telephone follow-ups by a clinical psychologist. The program will be evaluated in its effectiveness in reducing depressive and anxiety symptoms, psychological distress, negative thoughts and negative emotions and increasing positive thoughts and positive emotions.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
400 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Development of an Online Cognitive Behavioral Intervention Program to Reduce Depressive Symptoms for Hong Kong People With Depression
Actual Study Start Date :
Jan 1, 2019
Anticipated Primary Completion Date :
Jun 30, 2022
Anticipated Study Completion Date :
Jun 30, 2022

Arms and Interventions

Arm Intervention/Treatment
Experimental: web-based cognitive behavioral intervention

The web-based program is consisted of 8 online modules, forum, internal messaging, reminder, online assessment and online booking. Each online module contains mood check, animation briefing and debriefing, case demonstration videos, session review and exercise. Blended mode is adopted to deliver service, which includes the online program, two face-to-face session and 2 telephone follow-ups with a clinical psychologist.

Other: Confront and Navigate Depression Online (CANDO)
This study adopts a blended mode of service delivery, which included both online and offline intervention. The online intervention includes 8 weekly online model, animation briefing and debriefing, case demonstration video, exercise, forum, internal messaging, reminder, online assessment, session review and online booking system. The offline intervention includes two face-to-face sessions and two telephone follow-ups.

Experimental: app-based cognitive behavioral intervention

App-based cognitive behavioral intervention program The App-based program is consisted of 8 online modules, forum, internal messaging, reminder, online assessment and online booking. Each online module contains mood check, animation briefing and debriefing, case demonstration videos, session review and exercise. Blended mode is adopted to deliver service, which includes the online program, two face-to-face session and 2 telephone follow-ups with a clinical psychologist

Other: Confront and Navigate Depression Online (CANDO)
This study adopts a blended mode of service delivery, which included both online and offline intervention. The online intervention includes 8 weekly online model, animation briefing and debriefing, case demonstration video, exercise, forum, internal messaging, reminder, online assessment, session review and online booking system. The offline intervention includes two face-to-face sessions and two telephone follow-ups.

No Intervention: Wait-list control group

No intervention will be provided when the experimental group is receiving services, but the access to the app-based program will be delivered to the wait-list control group after the two experimental groups complete the service.

Outcome Measures

Primary Outcome Measures

  1. Beck Depression Inventory-II (BDI-II) [6 months]

    21-item rating scale for depressive symptoms

  2. Patient Health Questionnaire-9 (PHQ-9) [6 months]

    9-item rating scale for depressive symptoms.

Secondary Outcome Measures

  1. General Health Questionnaire-12 (GHQ-12) [6 months]

    12 item rating scale for psychological distress.

  2. Beck Anxiety Inventory (BAI) [6 months]

    21-item rating scale for symptoms of anxiety.

  3. Chinese Automatic Thoughts Questionnaire (CATQ) [6 months]

    20-item rating scale for automatic thoughts.

  4. Chinese Affect Scale (CAS) [6 months]

    20-item rating scale for positive and negative emotions of Chinese-speaking people.

  5. Negative effects Questionnaire (NEQ) (administered at post-test only) [6 months]

    20-item rating scale for negative effects caused by psychological treatment

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 70 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Hong Kong resident

  • Has mild to moderate depressive symptoms

  • No suicidal risk in the past 3 months

  • Receive no face-to-face counselling since program commencement

  • Has access to a computer/smartphone with internet access

  • Has a valid email address

Exclusion criteria:
  • Has severe or no depressive symptoms

  • Has suicidal risk in the past 3 months

  • Currently receiving other psychological treatment

  • Suffer from severe psychiatric conditions, such as bipolar disorder or schizophrenia

  • Has no computer or smartphone with internet access

  • Has no valid email address

Contacts and Locations

Locations

Site City State Country Postal Code
1 Jiayan Pan Hong Kong Hong Kong

Sponsors and Collaborators

  • Hong Kong Baptist University
  • Stockholm University
  • Richmond Fellowship of Hong Kong
  • Caritas Wellness Link - Tsuen Wan
  • Dr. Chiu Siu Ning
  • Innovation and Technology Fund for Better Living

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Jiayan Pan, Associate Professor, Hong Kong Baptist University
ClinicalTrials.gov Identifier:
NCT04388800
Other Study ID Numbers:
  • ITB/FBL/5002/18/P
First Posted:
May 14, 2020
Last Update Posted:
Mar 18, 2022
Last Verified:
Mar 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Jiayan Pan, Associate Professor, Hong Kong Baptist University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Mar 18, 2022