Motivationally-Enhanced Brief Interpersonal Psychotherapy for Depressed Mothers of Ill Children

Sponsor

University of Pittsburgh (Other)

Overall Status

Completed

CT.gov ID

NCT00245193

Collaborator

(none)

Enrollment

Location

Duration (Months)

1.4

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study will investigate the effectiveness of motivationally-enhanced brief interpersonal psychotherapy (MI-IPT-B) in treating depression in mothers who bring their children to a child mental health clinic for psychiatric treatment.

Condition or Disease	Intervention/Treatment	Phase
Depression	Behavioral: Motivationally-Enhanced Interpersonal Psychotherapy	Phase 4

Detailed Description

Depression is a serious illness and is common in mothers who have children facing an illness. Research has shown that these mothers, in particular, need better coping skills and ways to relieve depressive symptoms. Helping mothers of ill children achieve better mental health may also be beneficial to their children. Studies have shown that psychotherapy is an effective treatment for depression, and often results in long-term improvements in depressive symptoms. This study will investigate the effectiveness of MI-IPT-B in treating depression in mothers who bring their children to a child mental health clinic for psychiatric treatment.

Participants in this open label study will be randomly assigned to receive either MI-IPT-B or facilitated referral to treatment as usual (F-TAU). Participants in both groups will undergo the same screening procedures following assignment to an intervention. The MI-IPT-B group will also receive one session of motivational therapy at the time of the initial screening procedures. Participants assigned to receive MI-IPT-B will report to the study site once weekly for therapy. This type of therapy will focus on improving the participants' relationships with their peers and the way that they perceive themselves. The F-TAU group will receive a referral for standard mental health care within the community health system. Both treatments will last 8 weeks. All participants will return to the study site at Week 14 and Month 6 for follow-up assessments of depressive symptoms.

Study Design

Study Type:

Interventional

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

None (Open Label)

Primary Purpose:

Treatment

Official Title:

Motivationally-Enhanced Brief Interpersonal Psychotherapy for Depressed Mothers of Ill Children (MI-IPT-B-II)

Study Start Date :

Apr 1, 2003

Actual Study Completion Date :

Mar 1, 2006

Outcome Measures

Primary Outcome Measures

Score on the Hamilton Rating Scale for Depression; measured at baseline, Week 14, and Month 6 []

Secondary Outcome Measures

Score on the Beck Depression Inventory; measured at baseline, Week 14, and Month 6 []

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 65 Years

Sexes Eligible for Study:

Female

Accepts Healthy Volunteers:

Inclusion Criteria

Biological or adoptive mother whose child between the ages of 6 and 18 is treated in the Services for Teens at Risk (STAR) Center or the Center for Children and Families (CCF)
Mother lives with and has custody of the child receiving treatment
Meets DSM-IV criteria for current unipolar depressive disorder (e.g., dysthymic disorder, depressive disorder, or single or recurrent episodes of major depressive disorder)
Score of greater than 16 on the Beck Depression Inventory
Score of greater than 15 on the Hamilton Rating Scale for Depression (17-item)
Willingness to maintain existing stable dose of antidepressant medication throughout the study if currently on medication and still experiencing symptoms of depression
Willingness of child (treated in STAR clinic or CCF) to give informed consent

Exclusion Criteria:

Currently receiving antidepressant medication at sub-therapeutic doses or at therapeutic doses but for an inadequate period of time to assess response
Current dose of medication has not been stable for at least 8 weeks prior to study enrollment
Suicidal or homicidal
Requires hospitalization
At risk for child abuse or neglect and requires intervention
Simultaneous psychotic disorder or organic mental disorder
History of drug or alcohol abuse within 6 months of study enrollment
History of a prior manic episode
Significant medical illness that might explain depressive symptoms (e.g., epilepsy, autoimmune disorders, liver dysfunction, unstable endocrine disease)
Not fluent in English
Severe cognitive deficits that would interfere with psychotherapy treatment
Currently receiving another form of individual psychotherapy or couples therapy (except for participation in a support group, such as Alcoholics Anonymous)

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Western Psychiatric Institute and Clinic	Pittsburgh	Pennsylvania	United States	15231

Sponsors and Collaborators

University of Pittsburgh

Investigators

Principal Investigator: Holly Swartz, MD, University of Pittsburgh

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

, ,

ClinicalTrials.gov Identifier:

NCT00245193

Other Study ID Numbers:

K23MH064518
DSIR 8K-RTAT

First Posted:

Oct 27, 2005

Last Update Posted:

Jun 25, 2013

Last Verified:

Jun 1, 2013

Keywords provided by , ,

Major Depression

Additional relevant MeSH terms:

Depression

Study Results

No Results Posted as of Jun 25, 2013