Dermatological Abnormalities in Beta-thalassemia Major
Sponsor
Assiut University (Other)
Overall Status
Unknown status
CT.gov ID
NCT03894605
Collaborator
(none)
125
13
Study Details
Study Description
Brief Summary
to study the frequency and pattern of dermatological abnormalities in egyptian childern with beta thalassemia.relationof abnormalities to duration of disease and frequency of transfusion
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
thalassemia refers to agroup of inherited disease characterized by decreased or absent synthesis of normal globin .skinvdisorders are usually neglected and frequently underdiagnosed among these patients.skin disease specially pruritus and xerosis are observed highly frequently in patients with beta-thalassemia.pityriasis alba is arelatively common skin disorder.the trophic skin changes and leg ulcers occurred after the age of 15 years
Study Design
Study Type:
Observational
Anticipated Enrollment
:
125 participants
Observational Model:
Other
Time Perspective:
Prospective
Official Title:
Assessment ofDermatological Abnrmalities in Beta-thalassemia Major in Assiut University Pediatric Hospital
Anticipated Study Start Date
:
Mar 2, 2020
Anticipated Primary Completion Date
:
Mar 2, 2021
Anticipated Study Completion Date
:
Apr 2, 2021
Outcome Measures
Primary Outcome Measures
- The percentage of patients with dermatological disorders due to iron overload Iron overload cause dermatological abnormalities [one month]
the number of patients who develop any dermatological disorder as a result of iron overload after frequent blood transfusion
Eligibility Criteria
Criteria
Ages Eligible for Study:
2 Years
to 18 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusio2n Criteria:
- clinical diagnosis of dermatological abnormalities in thalassemic patient. must be on chelator
Exclusion Criteria:
- patient with other hemolytic anemia. childern with any abnormalities prior to the diagnosis of thalassemi
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Assiut University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
Responsible Party:
Neveen Mamdoh Farag,
Principal investigator,
Assiut University
ClinicalTrials.gov Identifier:
NCT03894605
Other Study ID Numbers:
- DBTM
First Posted:
Mar 28, 2019
Last Update Posted:
Mar 28, 2019
Last Verified:
Mar 1, 2019
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: