Novel Electrolyzed Water Spray Treatment Mild Dermatophytosis
Study Details
Study Description
Brief Summary
The purpose of this study is to test whether spraying the skin of patients of patients by use of the novel electrolyzed water spray will produce improvement in the condition of mild dermatophytosis.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
Recently, water spray containing a mixture of dissolved hydroxyl radicals, H2, O2, O3, and hydrogen peroxide were instantly generated by tap water and a novel electrolyzed water device. In brief, the scientists use the abrasion-resistant, heat-resisting conductive diamond material coating the key part of electrolyzed water device to directly make the tap water into a water spray containing a mixture of dissolved hydroxyl radical, H2, O2, O3, hydrogen peroxide, namely the advanced oxidizing water. Importantly, water spray containing a mixture of dissolved hydroxyl radicals, H2, O2, O3, and hydrogen peroxide does not release gaseous ozone <0.1mg/m3 to the immediate environment that meets the requirement of environmental safety. This is an open-label, single-arm, and before and after treatment comparison study. This study uses this novel electrolyzed water device and the water spray to treat mild dermatophytosis. In brief, 14 patients with mild dermatophytosis, male 6, female 8, average age 45±25 are included. Treatment is to spray the diseased area until about half a bottle (200ml) of water is consumed, 2 times a day, 7 days.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Mild dermatophytosis and one treatment Study staff will use the novel electrolyzed water spray device and spray for approximately 10 minutes on the participant's diseased area until half a bottle (200ml) of water is used. |
Device: The novel electrolyzed water spray
The researcher used electrolyzed water or piped water to treat the diseased area two times a day for five days. The trial consists of 7 study visits (day 1-day 7). The reduction in the disease area of discomfort or itching scores and promoting healing of the damaged skin of patients with mild dermatophytosis event assessments will be performed at each visit. Safety analysis will be assessed based on the reports of adverse events during the study.
|
Outcome Measures
Primary Outcome Measures
- An itching scale made by modifying the Numeric Pain Rating Scale (NPRS) [7 days]
This Score is based on descriptions of the itching that patients rate 0-10 to assess the condition of their mild dermatophytosis. A higher score means a worse outcome. 0 means "no itching " and 10 means "the most itching".
Secondary Outcome Measures
- A skin signs scale made by modifying the Numeric Pain Rating Scale (NPRS). [7 days]
The skin signs scale evaluates the disease-damaged skin replaced by fresh and healthy skin. This Score is based on descriptions of darkness or redness, swelling and dryness, broken surface, and reduced diseased skin area patients rate 0-10. A higher score means a worse outcome.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
mild dermatophytosis accompanied by significant itching symptom
-
Patient > 18 years old.
Exclusion Criteria:
-
severe dermatophytosis.
-
80 years or older.
-
Pregnant or breastfeeding women.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Changchun Jiahe Surgery Hospital | Jilin | Changchun | China | 130041 |
Sponsors and Collaborators
- Dove Medical Press Ltd
- The Affiliated Hospital of Qingdao University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- jia19650225