Determination of the Red Cell Distribution Width, NT-proBNP and cTnT in Acute Myocardial Infarction Patients

Sponsor

Sohag University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05677503

Collaborator

(none)

Enrollment

6.4

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

Condition or Disease	Intervention/Treatment	Phase
Myocardial Infarction	Diagnostic Test: CBC Diagnostic Test: (NT-proBNP) Diagnostic Test: (cTnT)

Detailed Description

Patients and methods:

Type of study: Observational prospective study
Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit.
Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients.
Study Methods:
A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge.

Full history:
Personal history: e.g. age, sex and smoking.
Family history of cardiac diseases
Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history
Detailed clinical examination
Electrocardiogram
Laboratory investigation:
Routine investigation in the form of CBC including RDW
Specific investigation which include NT-proBNP and cTnT

Study Design

Study Type:

Observational

Anticipated Enrollment :

30 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

Determination of the Relationship Between Red Cell Distribution Width, NT-proBNP and cTnT in Acute Myocardial Infarction Patients

Anticipated Study Start Date :

Jan 15, 2023

Anticipated Primary Completion Date :

Jun 30, 2023

Anticipated Study Completion Date :

Jul 30, 2023

Outcome Measures

Primary Outcome Measures

complete blood count (CBC) [7 months]
measurement of CBC levels will be performed
Level of (NT-proBNP) [7 months]
measurement of serum NT-proBNP level will be performed
Level of (cTnT) [7 months]
measurement of cTnT level will be performed

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 80 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

patients diagnosed as acute myocardial infarction

Exclusion Criteria:

Patient with

Decompensated heart failure
Pulmonary hypertention
Acute pulmonary embolism
Septic shock

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Sohag University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Hemat Kamel Maarouf, Resident doctor at clinical and chemical pathology department, Sohag University

ClinicalTrials.gov Identifier:

NCT05677503

Other Study ID Numbers:

Sohag_Med_22_12_07

First Posted:

Jan 10, 2023

Last Update Posted:

Jan 12, 2023

Last Verified:

Jan 1, 2023

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Myocardial Infarction

Infarction

Study Results

No Results Posted as of Jan 12, 2023