Snacks, Smiles and Taste Preferences
Study Details
Study Description
Brief Summary
The research study is designed is to determine whether children's acceptance of low sugar snacks, most preferred level of sweet and salty taste, and dietary intake of added sugars changes after repeated exposure to snacks lower in sweetness when compared to the control group.
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Detailed Description
This is a longitudinal, randomized, within- and between- subject study of children and their mothers to determine whether children's repeated exposure to snacks lower in sweetness and mothers' educational lessons about dental health and nutrition (intervention group) affects children's acceptance of low sugar snacks, most preferred level of sweet and salty taste, and dietary intake of added sugars when compared to the control group.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: Low Sweet Children in intervention group will be provided with daily snacks lower in added sugar and sweetness and their mothers will receive educational lessons on dental care, reading food labels, and nutrition that support the goals of reducing "sweet" exposure and added sugar intake. |
Behavioral: Low Sweet
Children in the experimental group get repeated exposure to lower sweet snacks and mothers get education lessons on dental care, reading food labels, portion size, and nutrition.
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Sham Comparator: Regular Sweet Children in the regular sweet control group will be provided with common snacks fed to children of this age and mothers will be given education lessons on portion size, physical activity, sleep, screen time and, at the end of the trial, dental care. |
Behavioral: Regular Sweet
Children in sham comparator get typical snacks and mothers get education lessons on portion size, physical activity, sleep, and screen time.
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Outcome Measures
Primary Outcome Measures
- Change is being assessed in the children's level of taste preferences [From timepoint 0 (baseline Monell visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month=end of intervention) and T5 (5 month which is 1 month post-intervention delay)]
Level of tastant (sucrose, salt) most preferred as determined by Monell forced choice tracking method [range: 0.09 to 1.05 M] measured at baseline, 2 months, 4 months (end of intervention), 1 month postintervention
- Change is being assessed in the children's liking of snacks low in sweetness [From timepoint 0 (baseline Temple visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month, end of intervention) and T5 (5 month, which is 1 month post-intervention delay)]
Children's grouping of the taste of novel snacks as liked or disliked as determined by lab-based forced-choice testing procedures; following grouping of snacks into liked and disliked, snacks will be ranked for most liked to most disliked [range: 4-6].
- Change is being assessed in the children's intake of snacks low in sweetness [From timepoint 0 (baseline Temple visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month= end of intervention) and T5 (5 month which is 1 month, post-intervention delay)]
Children's intake of novel snacks in grams, as determined by lab-based testing feeding procedures which are digitally recorded and later analyzed for behavioral responses during feeding; higher intake and/or less facial expressions of distaste, greater acceptance
Secondary Outcome Measures
- Change is being assessed in levels of hair biomarker for added sugar intake [From timepoint 0 (baseline Temple visit at start of intervention) to T4 (4 month visit=end of intervention)]
Estimates of added sugar intake will be determined via stable isotope ratio mass spectrometry methods on hair samples collected at the start (T0) and end of 4-month intervention (T4)
- Concordance of hair biomarker for added sugar intake among mother-child dyads [Relationship between hair biomarker levels at timepoint 0 (baseline Temple visit at start of intervention) and at T4 (4 month visit=end of intervention)]
Estimates of added sugar intake will be determined via stable isotope ratio mass spectrometry methods on hair samples collected from mother and child at the start (T0) and end of 4-month intervention (T4) end of the 4-month intervention period (T4) to determine concordance among mother-child dyads
- Change is being assessed in dietary intake of energy from added sugar and other sources [From timepoint 0 (baseline Temple visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month, end of intervention) and T5 (5 month, which is 1 month post-intervention delay)]
Dietary intake (g/day) will be determined from Automated Self-Administered Recall System (ASA24) and Diet History Questionnaire III completed by mothers for her child and herself, and adjusted for body weight of the individual (child, mother)
- Change is being assessed in liking-based dietary intake survey [From timepoint 0 (baseline Temple visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month, end of intervention) and T5 (5 month, which is 1 month post-intervention delay)]
Dietary intake of foods as determined by measurements of the degree of dislike or like for a variety of foods and beverages (e.g., sweet/fat, fruit, vegetables) as well as experiences and activities; range: -100 (maximal dislike) to 100 (maximal like)]. The items in a given category (e.g., fruits; sweets/fats; healthy foods) are combined and averaged [range: -100 to 100; higher numbers reflect greater liking and intake]. The preschool adapted liking survey (PALS) is used for children and the adult liking survey (ALS) is used for mothers
- Monitoring of individual differences in parenting feeding styles [From timepoint 0 (baseline visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month, end of intervention) and T5 (5 month, which is 1 month post-intervention delay)]
Mothers will complete the 19-item Child Feeding Styles and Practices Questionnaire [CFSQ]. Each item is scored from 1 (never) to 5 (always). Scores are averaged and categorized into one of four feeding styles: authoritative, authoritarian, indulgent and uninvolved; higher scores represent more of the feeding style
- Monitoring of individual differences in children's appetitive drive [From timepoint 0 (baseline visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month, end of intervention) and T5 (5 month, which is 1 month post-intervention delay)]
Mothers will complete the 26-item Children's Eating Behavior Questionnaire [CEBQ]. Each item is scored from 1 (never) to 5 (always) and are averaged and categorized into aspects of child eating (e.g., enjoyment of food, food responsiveness, satiety responsiveness, emotional overeating; emotional undereating, food fussiness); higher numbers reflect more of the behavior
- Monitoring of individual differences in children's palatable eating motivation [From timepoint 0 (baseline visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month, end of intervention) and T5 (5 month, which is 1 month post-intervention delay)]
Mothers will complete the 19-item Kids Palatable Eating Motive Scales (KPEMS) questionnaire; each item is scored from 1 (child almost never/never exhibits behavior) to 5 (child almost always/always exhibits behavior). Scores are averaged and categorized to reflect motives for intake of palatable foods (e.g., to socialize, cope, fit in or conform, for reward enhancement); higher numbers reflect more of the motivation
- Monitoring of individual differences in mothers' palatable eating motivation [From timepoint 0 (baseline visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month, end of intervention) and T5 (5 month, which is 1 month post-intervention delay)]
Mothers will complete the 19-item Palatable Eating Motive Scales (PEMS) questionnaire; each item is scored from 1 (almost never/never exhibits behavior) to 5 (almost always/always exhibits behavior). Scores are averaged and categorized to reflect motives for intake of palatable foods (e.g., to socialize, cope, fit in or conform, for reward enhancement); higher numbers reflect more of the motivation
- Monitoring of weight [From timepoint 0 (baseline visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month= end of intervention) and T5 (5 month which is 1 month, post-intervention delay)]
Children's weight will be measured in kg; these measures will be converted to weight for age Z scores which provide measures of anthropometry adjusted age and sex.
- Monitoring of height [From timepoint 0 (baseline visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month= end of intervention) and T5 (5 month which is 1 month, post-intervention delay)]
Children's height will be measured in cm; these measures will be converted to height for age Z scores which provide measures of anthropometry adjusted age and sex.
- Monitoring of body mass index [From timepoint 0 (baseline visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month= end of intervention) and T5 (5 month which is 1 month, post-intervention delay)]
Children's height will be measured in cm and weight in kg; these measures will be combined to determine BMI (kg/m2) and then converted to BMI Z scores which provide measures of anthropometry adjusted age and sex.
- Monitoring of waist and hip measurements [From timepoint 0 (baseline visit at start of intervention) to T1 (1 month), T2 (2 month), T3 (3 month), T4 (4 month= end of intervention) and T5 (5 month which is 1 month, post-intervention delay)]
Children's waist and hip circumference will be measured in cm; measurements will be combined to calculate waist-to-hip ratio
- Taste receptor genotype [At timepoint 0 (baseline Monell visit at start of intervention)]
Saliva with DNA will be collected for determination of allellic variants of known taste receptor genes to conduct exploratory analysis of genomic influence on sweet taste preference and response to intervention
Eligibility Criteria
Criteria
Inclusion Criteria:
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English speaking mother 18 years or older
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Mother has primary responsibility for the eligible child's care
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Mother has primary responsibility for feeding the eligible child
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Mother is responsible for purchasing food for the family
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Mother must be willing to refrain from eating food and beverages high in added sugars in the eligible child's presence for the duration of the study
Exclusion Criteria:
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Child is in full-day daycare or school
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Child is currently on a special diet (e.g. weight management programs)
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Child has severe food allergies (e.g. gluten, peanuts)
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Child has medical conditions know to affect growth or eating (e.g. diabetes, cystic fibrosis)
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Mother is a current smoker
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Monell Chemical Senses Center | Philadelphia | Pennsylvania | United States | 19104 |
2 | Temple University | Philadelphia | Pennsylvania | United States | 19140 |
Sponsors and Collaborators
- Temple University
- Monell Chemical Senses Center
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Investigators
- Principal Investigator: Julia Mennella, PhD, Monell Chemical Senses Center
- Principal Investigator: Jennifer O Fisher, PhD, Temple University
Study Documents (Full-Text)
None provided.More Information
Publications
- Hughes SO, Power TG, Orlet Fisher J, Mueller S, Nicklas TA. Revisiting a neglected construct: parenting styles in a child-feeding context. Appetite. 2005 Feb;44(1):83-92. Epub 2004 Nov 13.
- Martignon S, González MC, Tellez M, Guzmán A, Quintero IK, Sáenz V, Martínez M, Mora A, Espinosa LF, Castiblanco GA. Schoolchildren's tooth brushing characteristics and oral hygiene habits assessed with video-recorded sessions at school and a questionnaire. Acta Odontol Latinoam. 2012;25(2):163-70.
- Mennella JA, Finkbeiner S, Lipchock SV, Hwang LD, Reed DR. Preferences for salty and sweet tastes are elevated and related to each other during childhood. PLoS One. 2014 Mar 17;9(3):e92201. doi: 10.1371/journal.pone.0092201. eCollection 2014.
- Mennella JA, Lukasewycz LD, Griffith JW, Beauchamp GK. Evaluation of the Monell forced-choice, paired-comparison tracking procedure for determining sweet taste preferences across the lifespan. Chem Senses. 2011 May;36(4):345-55. doi: 10.1093/chemse/bjq134. Epub 2011 Jan 12.
- Mennella JA, Pepino MY, Lehmann-Castor SM, Yourshaw LM. Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression. Addiction. 2010 Apr;105(4):666-75. doi: 10.1111/j.1360-0443.2009.02865.x. Epub 2010 Feb 9.
- Nash SH, Kristal AR, Hopkins SE, Boyer BB, O'Brien DM. Stable isotope models of sugar intake using hair, red blood cells, and plasma, but not fasting plasma glucose, predict sugar intake in a Yup'ik study population. J Nutr. 2014 Jan;144(1):75-80. doi: 10.3945/jn.113.182113. Epub 2013 Nov 6.
- Sharafi M, Rawal S, Fernandez ML, Huedo-Medina TB, Duffy VB. Taste phenotype associates with cardiovascular disease risk factors via diet quality in multivariate modeling. Physiol Behav. 2018 Oct 1;194:103-112. doi: 10.1016/j.physbeh.2018.05.005. Epub 2018 May 8.
- Vandeweghe L, Verbeken S, Moens E, Vervoort L, Braet C. Strategies to improve the Willingness to Taste: The moderating role of children's Reward Sensitivity. Appetite. 2016 Aug 1;103:344-352. doi: 10.1016/j.appet.2016.04.017. Epub 2016 Apr 19.
- Wardle J, Guthrie CA, Sanderson S, Rapoport L. Development of the Children's Eating Behaviour Questionnaire. J Child Psychol Psychiatry. 2001 Oct;42(7):963-70.
- 24653
- R01DC016616