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CGMSexercise: Aerobic Training, Aerobic-resistance Training and Glucose Profile (CGMS) in Type 2 Diabetes

Sponsor
Hospital de Clinicas de Porto Alegre (Other)
Overall Status
Completed
CT.gov ID
NCT00887094
Collaborator
(none)
14
Enrollment
1
Location
2
Arms
22
Duration (Months)
0.6
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Acute aerobic exercise
  • Behavioral: Acute aerobic-resistance exercise
 N/A

Detailed Description

Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

Study Design

Study Type:
Interventional
Actual Enrollment :
14 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Acute and Subacute Effects of Aerobic Training vs Aerobic/Resistance Training Upon Glucose Profile Evaluated Through Continuous Glucose Monitoring System in Type 2 Diabetes
Study Start Date :
Jun 1, 2009
Actual Primary Completion Date :
Mar 1, 2011
Actual Study Completion Date :
Apr 1, 2011

Arms and Interventions

Arm Intervention/Treatment
Experimental: Aerobic exercise

One bout of aerobic physical training will be performed on a cycle ergometer for 50 min

Behavioral: Acute aerobic exercise
Aerobic exercise (on a cycle ergometer, for 50 min)
Other Names:
  • There are no other names

    		•
    Experimental: Aerobic-resistance exercise

    One bout of aerobic-resistance physical training will be performed on a cycle ergometer added by a strenght training for 50 min (total)

    Behavioral: Acute aerobic-resistance exercise
    Aerobic-resistance exercise (on a cycle ergometer plus strength training, for 50 min in total)
    Other Names:
  • There are no other names

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Reduction of the prevalence of hyperglycemic peaks during a 24-h period after a bout of aerobic or aerobic/resistance exercise in type 2 diabetes patients on metformin/diet therapy. [24h]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    35 Years to 65 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • Type 2 diabetic patients treated with diet and metformin, 35-65 years old
    Exclusion Criteria:

    • Type 1 diabetic patients

    • Treatment with insulin or sulphonylureas or glitazones

    • Proliferative retinopathy

    • Severe autonomic neuropathy

    • Coronary artery disease

    • Baseline fasting plasma glucose>200 mg/dl

    • Peripheral artery disease

    • Amputation

    • Heart failure

    • Diabetic nephropathy

    • Renal failure

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Hospital de Clinicas de Porto Alegre Porto Alegre RS Brazil 90035-003

    Sponsors and Collaborators

    • Hospital de Clinicas de Porto Alegre

    Investigators

    • Principal Investigator: Beatriz Schaan, PhD, Hospital de Clinicas de Porto Alegre

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00887094
    Other Study ID Numbers:
    • 08-180
    First Posted:
    Apr 23, 2009
    Last Update Posted:
    Aug 4, 2011
    Last Verified:
    Aug 1, 2011
    Keywords provided by , ,
    Diabetes mellitus
    Exercise
    Endurance
    Resistance
    Continuous glucose monitoring system
    Additional relevant MeSH terms:
    Diabetes Mellitus
    Diabetes Mellitus, Type 2

    Study Results

    No Results Posted as of Aug 4, 2011