Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus
Sponsor
Aristotle University Of Thessaloniki (Other)
Overall Status
Completed
CT.gov ID
NCT03031834
Collaborator
(none)
Study Details
Study Description
Brief Summary
Patients with diabetes mellitus and definite autonomic and peripheral neuropathy were randomized to receive quinapril or no treatment for 2 years.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
| Phase 4 |
Study Design
Study Type:
Interventional
Official Title:
Efficacy of Administration of Angiotensin Converting Enzyme Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus
Study Start Date
:
Jan 1, 1999
Actual Primary Completion Date
:
May 1, 2001
Outcome Measures
Primary Outcome Measures
- Changes in R-R variation during deep breathing [2 years]
- Changes in response to Valsalva maneuver [2 years]
- Changes in 30:15 ratio [2 years]
- Changes in blood pressure response to standing [2 years]
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
and Older
Sexes Eligible for Study:
All
Inclusion Criteria:
- Diabetes mellitus with both autonomic and peripheral neuropathy
Exclusion Criteria:
- Hypertension, coronary heart disease
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Aristotle University Of Thessaloniki
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Konstantinos Tziomalos,
Assistant Professor of Internal Medicine,
Aristotle University Of Thessaloniki
ClinicalTrials.gov Identifier:
NCT03031834
Other Study ID Numbers:
- AristotleUMEDSCH095
First Posted:
Jan 26, 2017
Last Update Posted:
Jan 26, 2017
Last Verified:
Jan 1, 2017
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Additional relevant MeSH terms: