The Diagnostic Value of Acupoint Sensitization Based on Stable Angina Pectoris

Sponsor

West China Hospital (Other)

Overall Status

Unknown status

CT.gov ID

NCT03341663

Collaborator

(none)

183

Enrollment

Location

10.8

Anticipated Duration (Months)

16.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Investigators adopt cross-sectional study design to carry out the exemplary research in the aspects of disease diagnosis.This study is designed to confirm the hypothesis "acupoint sensitization is associated with a severity of angina pectoris, which may contribute to the diagnosis of stable angina pectoris". After the eligible participants recruited in group, the coronary artery lesions will be evaluated through coronary angiography and the Canadian Cardiovascular Society(CCS) angina pectoris classification will also be evaluated at the same time. The degree of acupoint sensitization will be tested by the electronic Von Frey instrument by one professional acupuncturist with total 12 acupoints, including Shenmen,Yinxi, Shaohao,Jiquan,Neiguan, Ximen, Quze, Shanzhong, Juque, Jueyinyu, Xinyu, Duyu. Analysis were conducted to explore relationships between the degree of acupoint sensitization, the degree of coronary artery stenosis and CCS angina pectoris classification. Diagnostic value will be further analyzed in the final step.

Condition or Disease	Intervention/Treatment	Phase
Stable Angina Pectoris Acupoint Sensitization Correlation Analysis Diagnostic Value	Combination Product: Coronary angiography,Canadian Cardiovascular Society angina pectoris classification for the severity of angina and electronic Von Frey instrument for testing the degree of acupoint sensitization

Study Design

Study Type:

Observational

Anticipated Enrollment :

183 participants

Observational Model:

Case-Only

Time Perspective:

Cross-Sectional

Official Title:

The Diagnostic Value of Acupoint Sensitization Based on Stable Angina Pectoris

Actual Study Start Date :

Dec 6, 2017

Anticipated Primary Completion Date :

Nov 1, 2018

Anticipated Study Completion Date :

Nov 1, 2018

Outcome Measures

Primary Outcome Measures

The degree of acupoint sensitization [About 1 hour]
The value will be obtained through the electronic Von Frey instrument
The degree of coronary artery stenosis [About 2 hours]
Data will be obtained through coronary angiography
Canadian Cardiovascular Society angina pectoris classification [About 1 hours]

Eligibility Criteria

Criteria

Ages Eligible for Study:

35 Years to 80 Years

Sexes Eligible for Study:

All

Inclusion Criteria:

Patients meet the diagnostic criteria of ACC/AHA angina pectoris of coronary heart disease
The frequency of angina attacks were greater or equal to twice a week over the previous 3 months
Patients agree to do coronary angiography examination and sign the informed consent.

Exclusion Criteria:

People with mental disabilities and intelligent obstacle
Patients who can't accomplish the detection of acupoint sensitization
Patients with allergic condition, especially the contrast media
Patients with acute myocardial infarction, unstable angina, during arrhythmia and serious diseases which can affect the blood supply of myocardial
Patients with skin or peripheral nerve paresthesia, pain or the detect area of skin ulcerate
Pregnant or lactating women
Patients who undergoing other clinical trials