Diaphragmatic and Pulmonary US for Extubation Success Prediction
Study Details
Study Description
Brief Summary
The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit. The investigators' null hypothesis is the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound can not predict the success of extubation in adult patients hospitalized in the intensive care unit.
The alternative hypothesis is the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.
The study is a no experimental study of diagnostic test, prospective with longitudinal capture. The study will consist of two parts: the first with the aim of finding the values best combination of sensitivity and specificity compared to extubation success for diaphragmatic shortening fraction and the number of lung quadrants with lines B. In the second part the study will make the prospective validation of these values.
Study Design
Outcome Measures
Primary Outcome Measures
- Extubation success [72 h after extubation]
The investigators consider successful extubation when the patient does not require reintubation within 72 hours of its extubation
Eligibility Criteria
Criteria
Inclusion Criteria:
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18 years of older
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Hospitalized in medical or surgical intensive care unit
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Successful spontaneous ventilation trial
Exclusion Criteria:
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Patients reintubated after a first failure after extubation
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Injuries to prevent conduct ultrasound
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Pregnancy
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History of neuromuscular disease
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Brain injury that prevented adequate protection of the airway (Glasgow Coma Scale <8)
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Unilateral or bilateral Pneumothorax
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Presence of chest tube in right hemothorax
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Right subphrenic abscess
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Known uni- or bilateral phrenic nerve injury
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Unilateral or bilateral diaphragmatic Paralysis
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Unwillingness of the patient or guardian to participate in the study
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | UANL University Hospital | Monterrey | Nuevo León | Mexico | 64000 |
Sponsors and Collaborators
- Hospital Universitario Dr. Jose E. Gonzalez
Investigators
- Study Director: Julio E González, MD, Universidad Autónoma de Nuevo León
Study Documents (Full-Text)
None provided.More Information
Publications
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- Criner GJ. Measuring diaphragm shortening using ultrasonography to predict extubation success. Thorax. 2014 May;69(5):402-4. doi: 10.1136/thoraxjnl-2013-204920.
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- Soummer A, Perbet S, Brisson H, Arbelot C, Constantin JM, Lu Q, Rouby JJ; Lung Ultrasound Study Group. Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress*. Crit Care Med. 2012 Jul;40(7):2064-72. doi: 10.1097/CCM.0b013e31824e68ae.
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- NM16-00003