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Dietary Metabolic Signatures in Health Study

Sponsor
Zhejiang University (Other)
Overall Status
Recruiting
CT.gov ID
NCT05233917
Collaborator
(none)
2,290
Enrollment
1
Location
55
Anticipated Duration (Months)
41.6
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Investigations of associations of food nutrition and safety factors with the risk of chronic diseases are limited and studies in China are still lacking. The investigators aim to collect basic characteristics of participants at baseline, including sex, age, smoking, exercise, marriage, education level, dietary factors, and so on, to assess the association of food nutrition and safety factors including various food items, dietary fatty acids, and internal biomarkers of food contaminants such as acrylamide and 3-MCPD with various chronic diseases in a Chinese middle-aged and elderly population. We will use multi-omics technology to investigate the causal mechanisms. Results from this study will be valuable for chronic diseases prevention in China.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    2290 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Dietary Metabolic Signatures in Health Study （DMSHS）
    Actual Study Start Date :
    May 1, 2018
    Anticipated Primary Completion Date :
    Jun 1, 2022
    Anticipated Study Completion Date :
    Dec 1, 2022

    Outcome Measures

    Primary Outcome Measures

    1. Numbers of participants with metabolic syndrome [From entry into the study (baseline:2018-2022) until 2022]]

      metabolic syndrome

    2. Numbers of participants with obesity [From entry into the study (baseline:2018-2022) until 2022]]

      Obesity

    3. Numbers of participants with diabetes [From entry into the study (baseline:2018-2022) until 2022]]

      Diabetes

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    45 Years to 75 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Subject aged ≥45 and ≤74 years old

    • Subject has complete data on diet and follow-up time

    Exclusion Criteria:

    • had the major illness that had made personal life disabled

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Lanxi Red Cross Hospital Lanxi Zhejiang China 321100

    Sponsors and Collaborators

    • Zhejiang University

    Investigators

    • Principal Investigator: Weifang Zheng, Lanxi Red Cross Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Yu Zhang, Professor, Zhejiang University
    ClinicalTrials.gov Identifier:
    NCT05233917
    Other Study ID Numbers:
    • Cohort-DMSHS
    First Posted:
    Feb 10, 2022
    Last Update Posted:
    Feb 10, 2022
    Last Verified:
    Feb 1, 2022
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Yu Zhang, Professor, Zhejiang University
    Food safety
    Food nutrition
    Food contaminant
    Mult-omics
    Chronic diseases
    Additional relevant MeSH terms:
    Chronic Disease

    Study Results

    No Results Posted as of Feb 10, 2022