Differences in Sitting Versus Standing on Metabolic and Cardiovascular Measurements
Study Details
Study Description
Brief Summary
This investigations examined the effect that posture has on metabolic and cardiovascular measurements. Further, it will explore the potential for body weight status or physical activity to influence these relationships. All subjects will complete a seated condition and a standing condition in a counterbalanced manner.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
The purpose of the present study was to evaluate both metabolic and cardiovascular responses to acute bouts of computer work while sitting and standing. Cardiovascular measurements were made using continuous non-invasive blood pressure monitoring and metabolic measurements were made using indirect calorimetry. Subjects will be grouped and analyzed based upon the weight status of the subject. All subjects will complete a seated condition and a standing condition in a counterbalanced manner. Investigators hypothesize that metabolic and cardiovascular responses will be elevated in the standing condition compared to sitting.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Normal Weight Group is determined based upon subjects weight status. Subjects will preform computer work in the seated and standing position in a counterbalanced manner while metabolic and cardiovascular measurements are made. |
Behavioral: sit/stand
Subjects will be asked to both sit and stand during a single trial.
|
| Overweight/Obese Group is determined based upon subjects weight status. Subjects will preform computer work in the seated and standing position in a counterbalanced manner while metabolic and cardiovascular measurements are made. |
Behavioral: sit/stand
Subjects will be asked to both sit and stand during a single trial.
|
Outcome Measures
Primary Outcome Measures
- Heart Rate [Approximately 15 minutes in each condition (sitting and standing)]
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure heart rate based upon beat-by-beat finger pressure.
- Systolic Blood Pressure (SBP) [Approximately 15 minutes in each condition (sitting and standing)]
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure SBP based upon beat-by-beat finger pressure.
- Diastolic Blood Pressure (DBP) [Approximately 15 minutes in each condition (sitting and standing)]
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure DBP based upon beat-by-beat finger pressure.
- Oxygen Consumption [Approximately 15 minutes in each condition (sitting and standing)]
Oxygen consumption will be measured using indirect calorimetry.
- Carbon Dioxide Production [Approximately 15 minutes in each condition (sitting and standing)]
Carbon Dioxide will be measured using indirect calorimetry.
- Ventilation [Approximately 15 minutes in each condition (sitting and standing)]
Ventilation will be measured using indirect calorimetry.
- Respiratory Exchange Ration (RER) [Approximately 15 minutes in each condition (sitting and standing)]
RER will be calculated using oxygen and carbon dioxide value measure from indirect calorimetry.
Secondary Outcome Measures
- Height [1 minute]
Standard stadiometer will be used to measure height in meters.
- Weight [1 minute]
Standard scale will be used to measure weight in kilograms.
- Body Mass Index (BMI) [1 minute]
Height in meters and weight in kilograms will be used to calculate BMI using the formula BMI = kg/m^2.
- Body Composition [Approximately 15 minutes]
Body composition will be measured using air displacement plethysmography.
- Total Peripheral Resistance (TPR) [Approximately 15 minutes in each condition (sitting and standing)]
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be uses to estimate TPR based upon beat-by-beat finger pressure.
- Stroke Volume [Approximately 15 minutes in each condition (sitting and standing)]
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to estimate TPR based upon beat-by-beat finger pressure.
- Cardiac Output (Q) [Approximately 15 minutes in each condition (sitting and standing)]
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to estimate Q based upon beat-by-beat finger pressure.
- Muscle Oxygen Saturation [Approximately 15 minutes in each condition (sitting and standing)]
Using Near-inferred spectroscopy muscle oxygen consumption will be monitored.
Eligibility Criteria
Criteria
Inclusion Criteria:
- healthy adult
Exclusion Criteria:
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Have a history of cancer, cardiac issues, hypertension, pulmonary disease, stroke, neurological or muscular dystrophy, uncontrolled diabetes, or any life threatening chronic conditions.
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Are currently being treated for infectious mononucleosis, hepatitis, pneumonia, or other infectious diseases.
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Are unable or unwilling to stand in one position continuously for 15-20 minutes at a time.
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Use nicotine products, or non-contraceptive hormonal therapy (birth control is okay).
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Are pregnant or trying to become pregnant.
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Are not between 18 and 50 years of age.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Montclair State University | Montclair | New Jersey | United States | 07043 |
Sponsors and Collaborators
- Montclair State University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
- 17-18-861