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Different Metabolic Characteristics in the Presence of Brown Adipose Tissue in Humans

Sponsor
Korea University (Other)
Overall Status
Completed
CT.gov ID
NCT01430338
Collaborator
(none)
90
Enrollment
1
Location

Study Details

Study Description

Brief Summary

Functional brown adipose tissue (BAT) exists in adult humans and can be detected by PET and especially during acute cold exposure. It is conceivable that BAT activity might reduce the risk of developing obesity since fat stores are used for thermogenesis, and a directed enhancement of adipocyte metabolism might have value in weight reduction. So it is important to know the different metabolic characteristics in human adults who have detected BAT. Therefore, the purpose of the investigators study is to compare different metabolic characteristics in the presence of brown adipose tissue in humans.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    90 participants
    Observational Model:
    Cohort
    Time Perspective:
    Cross-Sectional
    Official Title:
    Different Metabolic Characteristics in the Presence of Brown Adipose Tissue in Humans
    Study Start Date :
    Dec 1, 2010
    Actual Primary Completion Date :
    Dec 1, 2011

    Arms and Interventions

    Arm Intervention/Treatment
    BAT

    brown adipose tissue detected, undetected

    Outcome Measures

    Primary Outcome Measures

    1. presence metabolic syndrome [5 months]

    Secondary Outcome Measures

    1. BMI [5 months]

    2. visceral fat area [5 months]

    3. adipokines [5 months]

    4. sarcopenia [5 months]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    Female
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Patients who underwent 18FDG-PET/CT scan year between 2008-2010
    Exclusion Criteria:

    • History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)

    • Diabetes

    • Stage 2 hypertension

    • Severe renal or hepatic disease

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 korea University Guro Hospital Seoul Korea, Republic of

    Sponsors and Collaborators

    • Korea University

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    K. M. Choi, Professor, Korea University
    ClinicalTrials.gov Identifier:
    NCT01430338
    Other Study ID Numbers:
    • BAT
    First Posted:
    Sep 8, 2011
    Last Update Posted:
    Mar 17, 2015
    Last Verified:
    Sep 1, 2011
    Additional relevant MeSH terms:
    Metabolic Syndrome

    Study Results

    No Results Posted as of Mar 17, 2015