DISCARD: Discard:Characterisation of Colonic Polyps in Vivo

Sponsor

Imperial College London (Other)

Overall Status

Completed

CT.gov ID

NCT00888771

Collaborator

(none)

130

Enrollment

Location

Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Prospective study of accuracy of colonic polyp characterisation in vivo using high resolution white light endoscopy, narrow band imaging and chromoendoscopy.

Condition or Disease	Intervention/Treatment	Phase
Colorectal Polyps

Study Design

Study Type:

Observational

Actual Enrollment :

130 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Characterisation of Small Colonic Polyps in Vivo

Study Start Date :

Aug 1, 2008

Actual Primary Completion Date :

Feb 1, 2009

Actual Study Completion Date :

Jun 1, 2009

Arms and Interventions

Arm	Intervention/Treatment
1
2
3
4

Outcome Measures

Primary Outcome Measures

Accuracy of polyp characterisation [12 months]

Secondary Outcome Measures

Change in surveillance interval after formal histopathology [12 months]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Patients over 18 years of age, assessed as fit for routine colonoscopy
Patients attending for screening or surveillance colonoscopy meeting the following criteria:

Polyp surveillance with at least 3 adenomas or 1 adenoma>10mm at previous colonoscopy
Surveillance post colorectal cancer resection
Screening with positive faecal occult blood test