Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?

• Sponsor: Royal Brompton & Harefield NHS Foundation Trust (Other)
• Overall Status: Completed
• CT.gov ID: NCT01507415
• Collaborator: Medical Research Council (Other), The Hillingdon Hospitals NHS Foundation Trust (Other), West Hertfordshire Hospitals NHS Trust (Other)
• Enrollment: 226
• Locations: 2
• Duration (Months): 27
• Patients Per Site: 113
• Patients Per Site Per Month: 4.2

Study Details

Study Description

Brief Summary

This study aims to evaluate simple tests of physical function in hospitalised patients with chronic obstructive pulmonary disease (COPD) and to assess whether they can predict future hospital readmission. The Short Physical Performance Battery (SPPB) is a simple test of standing balance, usual walking speed (4-metre gait speed) and ability to stand from a chair, which reflects global physical functioning and frailty.

We hypothesise that the SPPB or 4-metre gait speed can predict future hospital readmissions.

Condition or Disease	Intervention/Treatment	Phase
Pulmonary Disease, Chronic Obstructive; Respiratory Tract Diseases; Lung Diseases; Lung Diseases, Obstructive; Bronchitis, Chronic; Pulmonary Emphysema; Disease Progression

Study Design

• Study Type: Observational
• Actual Enrollment: 226 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?
• Study Start Date: Nov 1, 2011
• Actual Primary Completion Date: Feb 1, 2013
• Actual Study Completion Date: Feb 1, 2014

Arms and Interventions

Arm	Intervention/Treatment
Exacerbation Patients with Chronic Obstructive Pulmonary Disease (COPD)

Outcome Measures

Primary Outcome Measures

1. Hospital readmission rate [3 months]

Secondary Outcome Measures

1. Hospital readmission rate [12 months]

2. Time to first hospital readmission [12 months]

3. Hospital Bed days [12 months]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 35 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Hospital admission with an exacerbation of COPD

• Must have capacity to consent

• Able to walk

Exclusion Criteria:

• Co-morbibities that limit walking ability

• Co-morbidities that make walking unsafe

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Hillingdon Hospital	Uxbridge		United Kingdom	UB8 3NN
2	Watford General Hospital	Watford		United Kingdom	WD18 0HB

Sponsors and Collaborators

• Royal Brompton & Harefield NHS Foundation Trust
• Medical Research Council
• The Hillingdon Hospitals NHS Foundation Trust
• West Hertfordshire Hospitals NHS Trust

Investigators

• Principal Investigator: William DC Man, MRCP PhD, NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust

Study Documents (Full-Text)

None provided.

More Information

Publications

• Volpato S, Cavalieri M, Sioulis F, Guerra G, Maraldi C, Zuliani G, Fellin R, Guralnik JM. Predictive value of the Short Physical Performance Battery following hospitalization in older patients. J Gerontol A Biol Sci Med Sci. 2011 Jan;66(1):89-96. doi: 10.1093/gerona/glq167. Epub 2010 Sep 22.

• Responsible Party: Royal Brompton & Harefield NHS Foundation Trust
• ClinicalTrials.gov Identifier: NCT01507415
• Other Study ID Numbers: 2011LF015H
• First Posted: Jan 10, 2012
• Last Update Posted: Nov 5, 2014
• Last Verified: Nov 1, 2014

• Keywords provided by Royal Brompton & Harefield NHS Foundation Trust: Cohort Studies; Longitudinal Studies; Patient Readmission; Hospitalization; Disability Evaluation
• Additional relevant MeSH terms: Bronchitis; Bronchitis, Chronic; Lung Diseases; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Respiratory Tract Diseases; Lung Diseases, Obstructive; Disease Progression; Emphysema

Study Results

No Results Posted as of Nov 5, 2014