Do Patients Suffering a Cardiac Arrest Present to the Ambulance Service With Symptoms in the Preceeding 48hrs?

• Sponsor: University Hospital Southampton NHS Foundation Trust (Other)
• Overall Status: Completed
• CT.gov ID: NCT04604639
• Collaborator: South Central Ambulance Service NHS Foundation Trust (Other)
• Enrollment: 200
• Location: 1
• Actual Duration (Months): 24.6
• Patients Per Site Per Month: 8.1

Study Details

Study Description

Brief Summary

A cardiac arrest is often preceeded by a varying period of physiological deterioration which if acted upon may prevent the cardiac arrest. We aim to review patients presenting to the ambulance service with cardiac arrest so see if they had contacted the ambulance service in the preceeding 48 hrs to understand if warning symptoms were missed or not acted upon appropriately.

Condition or Disease	Intervention/Treatment	Phase
Cardiac Arrest	Diagnostic Test: NEWS2 score

Detailed Description

The UK ambulance services are called to attend 60,000 out-of-hospital cardiac arrests (OHCA) each year. Hospital studies have shown that many patients who suffer an in-hospital cardiac arrest (IHCA) have been deteriorating for the preceeding 48 hrs and suggest that many IHCA are potentially avoidable if this deterioration is identified and actued on promptly. No similar study has been performed to see if patients suffering OHCA have also presented with warning signs in the preceeding 48 hrs that were overlooked.

Study Design

• Study Type: Observational
• Actual Enrollment: 200 participants
• Observational Model: Cohort
• Time Perspective: Retrospective
• Official Title: Do Patients Suffering an Out-of-hospital Cardiac Arrest Present to the Ambulance Service With Symptoms in the Preceeding 48hrs?
• Actual Study Start Date: Feb 1, 2018
• Actual Primary Completion Date: Feb 19, 2020
• Actual Study Completion Date: Feb 20, 2020

Arms and Interventions

Arm	Intervention/Treatment
Out-of-hospital cardiac arrest Patients suffering an out-of-hospital cardiac arrest to who the ambulance service was requested to attend.	Diagnostic Test: NEWS2 score; Patients seen by ambulance crews within the preceeding 48 hrs of their cardiac arrest will have a NEWS2 score performed to assess the level of physiological deterioration at the time of thei intial assessment.

Outcome Measures

Primary Outcome Measures

1. Out-of-hospital cardiac arrest [48 hours]

   Cardiac arrest following ambulance assessment

Eligibility Criteria

Criteria

• Ages Eligible for Study: N/A and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• All patients seen by SCAS ambulance crews and suffering a cardiac arrest within the following 48 hrs

Exclusion Criteria:

• None

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	South Central Ambulance Service	Otterbourne	Hampshire	United Kingdom	SO21 2RU

Sponsors and Collaborators

• University Hospital Southampton NHS Foundation Trust
• South Central Ambulance Service NHS Foundation Trust

Investigators

• Principal Investigator: Charles D Deakin, MD, Divisional Medical Director

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: University Hospital Southampton NHS Foundation Trust
• ClinicalTrials.gov Identifier: NCT04604639
• Other Study ID Numbers: 3724/18
• First Posted: Oct 27, 2020
• Last Update Posted: Apr 13, 2022
• Last Verified: Feb 1, 2020

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by University Hospital Southampton NHS Foundation Trust: Cardiac arrest; Ambulance; Triage; Deterioration
• Additional relevant MeSH terms: Heart Arrest

Study Results

No Results Posted as of Apr 13, 2022