Evaluation of Donated Human Embryos Following in Vitro Fertilization
Study Details
Study Description
Brief Summary
Couples who have created excess embryos while undergoing IVF procedures, and who do not wish to transfer those embryos or donate them to another couple may donate the extra embryos to research. The embryos are then used to develop improved laboratory techniques and conditions as well as testing the proficiency of laboratory staff.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
Undergoing IVF treatment often results in the production of more embryos than can safely be transferred at one time. These extra embryos are often cryopreserved for future use. In the event that a couple decides that they do not want to proceed with using cryopreserved embryos, these embryos can be discarded, donated to another couple, or donated to research.
Embryos that are donated to research are used to identify a group of parameters that have significant predictive value for assisted reproductive technology outcomes. We hope to develop future laboratory techniques as we gain a better knowledge of gamete development, fertilization and implantation. We will test, standardize and implement better methods for freezing embryos prior to employing these techniques in a clinical setting. We hope to develop new methods to optimize the determination of genes and chromosomes in embryos. We will test the proficiency of laboratory staff on techniques and/or procedures done in the IVF laboratory. This study WILL NOT:create embryos for research, transfer embryos to an individual, develop cell lines or clones.
Study Design
Outcome Measures
Primary Outcome Measures
- Freezing methods for embryos [duration of the study]
To test, standardize and implement better methods for the freezing of embryos prior to these techniques being implemented in the clinical setting.
Secondary Outcome Measures
- Development of New Methods [duration of the study]
The development of new methods to optimize the determination of genes and chromosomes in embryos
Eligibility Criteria
Criteria
Inclusion Criteria:
none
Exclusion Criteria:
none
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Reproductive Medicine Assoicates of New Jersey | Basking Ridge | New Jersey | United States | 07920 |
| 2 | Reproductive Medicine Assoicates of PA at Lehigh Valley | Allentown | Pennsylvania | United States | 18104 |
Sponsors and Collaborators
- Reproductive Medicine Associates of New Jersey
Investigators
- Principal Investigator: Richard T Scott, MD, Reproductive Medicine Associates of New Jersey
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.- RMA-00-05