Effect of Cyclic Tensional Force on Osteogenic Differentiation of Human Periodontal Ligament Stem Cells

Sponsor

National Taiwan University Hospital (Other)

Overall Status

Unknown status

CT.gov ID

NCT00172744

Collaborator

(none)

Enrollment

Locations

Duration (Months)

Patients Per Site

0.7

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to observe cyclic tensional force on the osteogenic differentiation of human periodontal ligament stem cells.

Condition or Disease	Intervention/Treatment	Phase
Healthy

Detailed Description

This study is to investigate the effect of the cyclic mechanical strain on the osteogenic differentiation of mesenchymal stem cells. Mesenchymal stem cells will be cultured from the periodontal ligament tissue of the premolars extracted due to orthodontic reason.

Study Design

Study Type:

Observational

Anticipated Enrollment :

20 participants

Time Perspective:

Prospective

Study Start Date :

Apr 1, 2005

Study Completion Date :

Jul 1, 2006

Outcome Measures

Primary Outcome Measures

Eligibility Criteria

Criteria

Ages Eligible for Study:

13 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Orthodontic patients who need to have premolars extracted

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	School of Dentistry, College of Medicine, National Taiwan University	Taipei		Taiwan
2	School of Dentistry, College of Medicine, National Taiwan University	Taipei		Taiwan