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The Electroencephalogram Analysis in the Differences Between Inhalation Anesthetic and Propofol.

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT04431557
Collaborator
(none)
268
Enrollment
1
Location
19.1
Actual Duration (Months)
14.1
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The investigators will record 120 patients who received general anesthesia, their EEG data recorded from Bispectral Index (BIS) machine for emperical mode decomposition (EMD) analysis, the investigators decomposed EEG signal to different oscillations and tried to observe the differences between hypnotic medications through EEG analysis.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The electroencephalography (EEG) is a noninvasive medical technique for monitoring and recording the electrical activity of brain. The Hilbert-Huang transform (HHT) was proposed to decompose EEG signal into intrinsic mode functions (IMF) which can obtain instantaneous frequency data and work well for data that is nonstationary and nonlinear.

    The relationship between frontal EEG patterns and hypnotics remain poorly understood. The investigators only can tell the increase in frontal EEG power and shift power to lower frequencies during general anesthesia from publications. The investigators are going to decompose EEG with HHT and find the energy shift during general anesthesia, compare with different anesthetics.

    The investigators will record 120 patients who received general anesthesia, their EEG data recorded from BIS machine for EMD analysis, the investigators decomposed EEG signal to different oscillations and tried to observe the differences between hypnotic medications through EEG analysis.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    268 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Prospective
    Official Title:
    The Electroencephalogram Analysis in the Differences Between Inhalation Anesthetic and Propofol.
    Actual Study Start Date :
    Jul 19, 2017
    Actual Primary Completion Date :
    Feb 19, 2019
    Actual Study Completion Date :
    Feb 19, 2019

    Outcome Measures

    Primary Outcome Measures

    1. The gamma, beta, alpha and theta power of EEG [the total duration inclusions in operation room]

      We will try to observe the differences between hypnotic medications through EEG decomposed and power analysis.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    20 Years and Older
    Sexes Eligible for Study:
    All
    Inclusion Criteria:

    • ASA I-II

    • scheduled surgery who need general anesthesia

    Exclusion Criteria:

    • allergy to the BIS patch

    • not suitable for general anesthesia

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 National Taiwan University Hospital Taipei Taiwan 10002

    Sponsors and Collaborators

    • National Taiwan University Hospital

    Investigators

    • Study Director: Feng-Fang Tsai, M.D., National Taiwan University Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    National Taiwan University Hospital
    ClinicalTrials.gov Identifier:
    NCT04431557
    Other Study ID Numbers:
    • 201509018RINB
    First Posted:
    Jun 16, 2020
    Last Update Posted:
    Jun 16, 2020
    Last Verified:
    Jul 1, 2017
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Respiratory Aspiration

    Study Results

    No Results Posted as of Jun 16, 2020