Comparison of Serum Calcium Level Between Preoperative Vitamin D and Non-vitamin D Regimen of Total Parathyroidectomy in End-stage Renal Failure Patients in Rajavithi Hospital

Sponsor

Rajavithi Hospital (Other)

Overall Status

Recruiting

CT.gov ID

NCT04967469

Collaborator

(none)

Enrollment

Location

Arms

44.9

Anticipated Duration (Months)

1.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This Research is compare about IV Calcium between end-stage renal failure patients who take vitamin D and non-vitamin D preoperative parathyroidectomy

Condition or Disease	Intervention/Treatment	Phase
End Stage Renal Disease	Drug: Calcitriol Drug: Alfacalcidol 0.5 MCG Oral Capsule	N/A

Study Design

Study Type:

Interventional

Anticipated Enrollment :

60 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

Single (Participant)

Primary Purpose:

Treatment

Official Title:

Comparison of Serum Calcium Level Between Preoperative Vitamin D and Non-vitamin D Regimen of Total Parathyroidectomy in End-stage Renal Failure Patients in Rajavithi Hospital

Actual Study Start Date :

Sep 1, 2020

Anticipated Primary Completion Date :

May 31, 2024

Anticipated Study Completion Date :

May 31, 2024

Arms and Interventions

Arm	Intervention/Treatment
Experimental: take calcitriol End-stage renal failure patients who is Hyperparathyroid with ESRD take calcitriol	Drug: Calcitriol end-stage renal failure patients who is hyperparathyroid with ESRD take calcidol preoperative Parathyroidectomy
Experimental: take alphacalcidol End-stage renal failure patients who is Hyperparathyroid with ESRD take 1-hydroxycholecalciferol (alfacalcidol)	Drug: Alfacalcidol 0.5 MCG Oral Capsule end-stage renal failure patients who is hyperparathyroid with ESRD take alfacalcidol preoperative Parathyroidectomy
No Intervention: control End-stage renal failure patients who is Hyperparathyroid with ESRD take standard treatment

Arm

Intervention/Treatment

Experimental: take calcitriol

End-stage renal failure patients who is Hyperparathyroid with ESRD take calcitriol

Drug: Calcitriol

end-stage renal failure patients who is hyperparathyroid with ESRD take calcidol preoperative Parathyroidectomy

Experimental: take alphacalcidol

End-stage renal failure patients who is Hyperparathyroid with ESRD take 1-hydroxycholecalciferol (alfacalcidol)

Drug: Alfacalcidol 0.5 MCG Oral Capsule

end-stage renal failure patients who is hyperparathyroid with ESRD take alfacalcidol preoperative Parathyroidectomy

No Intervention: control

End-stage renal failure patients who is Hyperparathyroid with ESRD take standard treatment

Outcome Measures

Primary Outcome Measures

Comparison of serum calcium level between patients who take Vitamin D and non-Vitamin D [4 year]
Comparison of serum calcium level between patients who take Vitamin D and non-Vitamin D